Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Emily K Moser"'
Autor:
Asif A Dar, Keisuke Sawada, Joseph M Dybas, Emily K Moser, Emma L Lewis, Eddie Park, Hossein Fazelinia, Lynn A Spruce, Hua Ding, Steven H Seeholzer, Paula M Oliver
Publikováno v:
PLoS Biology, Vol 19, Iss 2, p e3001041 (2021)
The capacity for T cells to become activated and clonally expand during pathogen invasion is pivotal for protective immunity. Our understanding of how T cell receptor (TCR) signaling prepares cells for this rapid expansion remains limited. Here we pr
Externí odkaz:
https://doaj.org/article/1ccf70c70537433581dda2a256654825
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0120169 (2015)
Influenza A virus (IAV) infection of the respiratory tract elicits a robust immune response, which is required for efficient virus clearance but at the same time can contribute to lung damage and enhanced morbidity. IL-21 is a member of the type I cy
Externí odkaz:
https://doaj.org/article/c0e4332c06b94cdbac7d9523d99ed354
Publikováno v:
PLoS Pathogens, Vol 10, Iss 8, p e1004315 (2014)
Influenza A virus (IAV) infection in the respiratory tract triggers robust innate and adaptive immune responses, resulting in both virus clearance and lung inflammation and injury. After virus clearance, resolution of ongoing inflammation and tissue
Externí odkaz:
https://doaj.org/article/0509da16a5354dde88c291e89c07af11
Autor:
Binod Kumar, Natania S. Field, Dale D. Kim, Asif A. Dar, Yanqun Chen, Aishwarya Suresh, Christopher F. Pastore, Li-Yin Hung, Nadia Porter, Keisuke Sawada, Palak Shah, Omar Elbulok, Emily K. Moser, De’Broski R. Herbert, Paula M. Oliver
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Cytokine signaling influences the differentiation of CD4+ T cells into varying functional subsets. Here the authors show that an E3 ubiquitin ligase Cul5 alters TH2 and TH9 development and absence of Cul5 in T cells results in higher levels of allerg
Externí odkaz:
https://doaj.org/article/d9e5115c68644de29848a0530e463a6f
Autor:
Yiping Wang, April Feswick, Vasiliki Apostolou, Petko M. Petkov, Emily K. Moser, Scott A. Tibbetts
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(32)
The germinal center (GC) plays a central role in the generation of antigen-specific B cells and antibodies. Tight regulation of the GC is essential due to the inherent risks of tumorigenesis and autoimmunity posed by inappropriate GC B cell processes
Autor:
Xueyang Zou, Seung-Chul Choi, Leilani Zeumer-Spataro, Yogesh Scindia, Emily K. Moser, Laurence Morel
Publikováno v:
Immunology letters. 247
Follicular helper T (T
Autor:
Emily K Moser, Joseph M Dybas, Steven H. Seeholzer, Lynn A. Spruce, Paula M. Oliver, Michael P. Cancro, Jennifer Roof
Publikováno v:
The Journal of Experimental Medicine
Itch is a catalytic ubiquitin ligase that prevents autoimmunity in humans and mice. Here, Moser et al. show that Itch negatively regulates B cell proliferation and metabolic fitness to limit antigen-driven B cell responses and antibody production aft
Autor:
Binod, Kumar, Natania S, Field, Dale D, Kim, Asif A, Dar, Yanqun, Chen, Aishwarya, Suresh, Christopher F, Pastore, Li-Yin, Hung, Nadia, Porter, Keisuke, Sawada, Palak, Shah, Omar, Elbulok, Emily K, Moser, De'Broski R, Herbert, Paula M, Oliver
Publikováno v:
Nature communications. 13(1)
Antigen encounter directs CD4
Autor:
Paula M. Oliver, Asif Amin Dar, Emily K Moser, Eddie Park, Lynn A. Spruce, Steven H. Seeholzer, Emma L. Lewis, Joseph M Dybas, Keisuke Sawada, Hossein Fazelinia, Hua Ding
Publikováno v:
PLoS Biology, Vol 19, Iss 2, p e3001041 (2021)
PLoS Biology
PLoS Biology
The capacity for T cells to become activated and clonally expand during pathogen invasion is pivotal for protective immunity. Our understanding of how T cell receptor (TCR) signaling prepares cells for this rapid expansion remains limited. Here we pr
Autor:
Sarah Beth Payne-Poff, Nancy Bunin, Maire A. Conrad, Emily K. Moser, Pierre Russo, Sarah E. Henrickson, Jonathan E. Markowitz, Paula M. Oliver, Kelly Maurer, Marcella Devoto, Noor Dawany, Judith R. Kelsen, Natania S. Field, E. John Wherry, Trusha Patel, Kelli W. Williams, Jason L. Freedman, Danielle E. Arnold, Kathleen E. Sullivan, Jennifer Heimall, Jing Wang
Publikováno v:
J Allergy Clin Immunol Pract
Background Mutations in ITCH, which encodes an E3 ubiquitin-protein ligase, can result in systemic autoimmunity and immunodeficiency. The clinical phenotype and mechanism of disease have not been fully characterized, resulting in a paucity of therape
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91995d23b1b0d01ba4636aeedf448a1e
http://hdl.handle.net/11573/1631219
http://hdl.handle.net/11573/1631219