Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Emily J. Lyons"'
Autor:
John F. McDyer, Mahzad Azimpouran, Valerie L. Durkalski-Mauldin, Robert G. Clevenger, Sharon D. Yeatts, Xutao Deng, William Barsan, Robert Silbergleit, Nahed El Kassar, Iulia Popescu, Dimiter Dimitrov, Wei Li, Emily J. Lyons, Sophia C. Lieber, Mars Stone, Frederick K. Korley, Clifton W. Callaway, Larry J. Dumont, Philip J. Norris, for the SIREN-C3PO Investigators
Publikováno v:
JCI Insight, Vol 8, Iss 8 (2023)
Multiple randomized, controlled clinical trials have yielded discordant results regarding the efficacy of convalescent plasma in outpatients, with some showing an approximately 2-fold reduction in risk and others showing no effect. We quantified bind
Externí odkaz:
https://doaj.org/article/7c19e4b03dd34452bc1b28ddfdf94cec
Autor:
Iulia, Popescu, Mark E, Snyder, Carlo J, Iasella, Stefanie J, Hannan, Ritchie, Koshy, Robin, Burke, Antu, Das, Mark J, Brown, Emily J, Lyons, Sophia C, Lieber, Xiaoping, Chen, John C, Sembrat, Payal, Bhatt, Evan, Deng, Xiaojing, An, Kelsey, Linstrum, Georgios, Kitsios, Ioannis, Konstantinidis, Melissa, Saul, Daniel J, Kass, Jonathan K, Alder, Bill B, Chen, Elizabeth A, Lendermon, Silpa, Kilaru, Bruce, Johnson, Joseph M, Pilewski, Joseph E, Kiss, Alan H, Wells, Alison, Morris, Bryan J, McVerry, Deborah K, McMahon, Darrell J, Triulzi, Kong, Chen, Pablo G, Sanchez, John F, McDyer
Publikováno v:
American journal of respiratory and critical care medicine. 205(12)
Autor:
Iulia Popescu, Mark E. Snyder, Carlo J. Iasella, Stefanie J. Hannan, Ritchie Koshy, Robin Burke, Antu Das, Mark J. Brown, Emily J. Lyons, Sophia C. Lieber, Xiaoping Chen, John C. Sembrat, Payal Bhatt, Evan Deng, Xiaojing An, Kelsey Linstrum, Georgios Kitsios, Ioannis Konstantinidis, Melissa Saul, Daniel J. Kass, Jonathan K. Alder, Bill B. Chen, Elizabeth A. Lendermon, Silpa Kilaru, Bruce Johnson, Joseph M. Pilewski, Joseph E. Kiss, Alan H. Wells, Alison Morris, Bryan J. McVerry, Deborah K. McMahon, Darrell J. Triulzi, Kong Chen, Pablo G. Sanchez, John F. McDyer
Publikováno v:
American journal of respiratory and critical care medicine, 205(12):1403-1418
RATIONALE: Lymphopenia is common in severe coronavirus disease (COVID-19), yet the immune mechanisms are poorly understood. As inflammatory cytokines are increased in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, we hypothes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a29e8bbc165be4febd0c036103e0cd28
https://repository.publisso.de/resource/frl:6435476
https://repository.publisso.de/resource/frl:6435476
Autor:
Antu Das, Sophia C. Lieber, Deborah McMahon, Bryan J. McVerry, M. Brown, Joseph M. Pilewski, Melissa Saul, Darrell J. Triulzi, S. Hannan, Joseph E. Kiss, Robin Burke, Daniel J. Kass, Bruce E. Johnson, Carlo J. Iasella, Alison Morris, Mark E. Snyder, Emily J. Lyons, Georgios D Kitsios, Xiaojing An, X. Chen, Bill B. Chen, John Sembrat, Ioannis Konstantinidis, Matthew R. Morrell, Alan Wells, Elizabeth A. Lendermon, John F. McDyer, R. Koshy, Pablo G. Sanchez, Iulia Popescu, Kong Chen, S. Kilaru, Jonathan K. Alder, Kelsey Linstrum
Lymphopenia is common in severe COVID-19 disease, yet the mechanisms are poorly understood. In 148 patients with severe COVID-19, we found lymphopenia was associated with worse survival. CD4+ lymphopenia predominated, with lower CD4+/CD8+ ratios in s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7761d184e27705ee2c2657b9f404b8d2
https://doi.org/10.1101/2021.06.02.446831
https://doi.org/10.1101/2021.06.02.446831
Autor:
Lulla Opatowski, Christophe Fraser, Jamie Griffin, Eric de Silva, Maria D Van Kerkhove, Emily J Lyons, Simon Cauchemez, Neil M Ferguson
Publikováno v:
PLoS Pathogens, Vol 7, Iss 9, p e1002225 (2011)
While in Northern hemisphere countries, the pandemic H1N1 virus (H1N1pdm) was introduced outside of the typical influenza season, Southern hemisphere countries experienced a single wave of transmission during their 2009 winter season. This provides a
Externí odkaz:
https://doaj.org/article/23f9d6aaa46b457d96e8dbcffe4be415
Autor:
Peter Holmans, Udo Seedorf, Beverley M. Shields, Peter McGruffin, Arne Pfeufer, Steve Eyre, Nathalie J. Prescott, Michael Boehnke, Valentina Moskovina, Abiodun Onipinla, Leena Peltonen, Nadira Yuldasheva, Peter M. Nilsson, Valeria Romanazzi, Vincent Mooser, Göran Berglund, Alistair S. Hall, Dominic P. Kwiatkowski, Barry Widmer, Benjamin F. Voight, Stefania Bandinelli, Mark M. Iles, Sven Bergmann, Thomas Meitinger, James P. Boorman, Simonetta Guarrera, Nazneen Rahman, Murielle Bochud, Graham A. Hitman, Emma Keniry, Nelson B. Freimer, Richard Dobson, Francis S. Collins, Gerjan Navis, Jennifer L. Pointon, Richard N. Bergman, Ruth J. F. Loos, Roberto Lorbeer, Carolina A. Braga Marcano, Christian Gieger, Florian Ernst, Xin Yuan, Catherine Potter, Hazel E. Drummond, Allan H. Young, George Kirov, John F. Peden, Helen Stevens, David Clayton, Mattijs E. Numans, Katherine Gordon-Smith, Anne Farmer, Alastair Forbes, M. Khalid Mohiuddin, John A. Todd, Christopher G. Mathew, David A. Collier, Mark I. McCarthy, Francesca Bredin, Clive M. Onnie, Dan Davidson, Markus Perola, Pamela Whittaker, Yvonne T. van der Schouw, Rathi Ravindrarajan, I. C.A. Spencer, Teresa Ferreira, Nilesh J. Samani, Serge Hercberg, Gonçalo R. Abecasis, Christopher J. Groves, Nicholas John Craddock, Angela Döring, Edward G. Lakatta, Muminatou Jallow, Wendy L. McArdle, David Bentley, Susana Eyheramendy, Uwe Völker, Christopher Newton-Cheh, Jaspal S. Kooner, Hugh Watkins, Gavin Lucas, H. T. Leung, Marjo Ritta Jarvelin, Johanna Kuusisto, Wiek H. van Gilst, Wendy Thomson, Lou R. Cardon, Harold Snieder, Marju Orho-Melander, Patricia B. Munroe, Toshiko Tanaka, Jeffrey C. Barrett, Azhar Maqbool, Henry Völzke, John M. C. Connell, Elaine R. Nimmo, John R. B. Perry, Michael R. Stratton, Ralph McGinnis, Pekka Jousilahti, Michiel L. Bots, Ian Jones, Elizabeth Meech, Matthew A. Brown, Johannie Gungadoo, Jian'an Luan, Jilur Ghori, Richard J. Dixon, N. Charlotte Onland-Moret, Fulvio Ricceri, Anthony J. Balmforth, Catherine E. Todhunter, Inês Barroso, Sheila Bingham, Timo T. Valle, Fredrik O. Vannberg, Diana Zelenika, Stephen Sawcer, Anneli Pouta, David M. Evans, Cuno S. P. M. Uiterwaal, Pilar Galan, Georg Homuth, Hannah Donovan, David J. Conway, Paul Elliott, Alessandra Allione, Paul E. de Jong, Miles Parkes, Amy Chaney, John C. Chambers, Toby Johnson, Isaac Subirana, Vesela Gateva, Cathryn M. Lewis, Christopher J. O'Donnell, Hana Lango, David Schlessinger, Mark J. Caulfield, Thorsten Reffelmann, Jamie Barbour, Karen L. Mohlke, Sarah E. Hunt, Thilo Winzer, Frances M K Williams, Christopher Mathew, I. Wallace, Anuj Goel, Jaakko Tuomilehto, Louise V. Wain, Gabriel Crawford, Samantha L. Hider, Detelinea Grozeva, Elaine K. Green, Paul D. Gilbert, Peter S. Braund, Jaume Marrugat, Rainer Rettig, Pim van der Harst, Yik Ying Teo, Andrew P. Morris, Guiseppe Matullo, Serena Sanna, Cristen J. Willer, Suzannah Bumpstead, Niall C. Taylor, Jacques S. Beckmann, Pierre Meneton, Elin Org, Luigi Ferrucci, Doug Easton, Sheila Seal, Joanne M. Heward, Anne U. Jackson, Eleftheria Zeggini, Rachel M. Freathy, Maris Laan, Paul Wordsworth, Sarah Nutland, Kerstin Koch, Sian Ceasar, Anders Hamsten, Judith M. Hussey, Tariq Ahmad, Derek P. Jewell, Paul Scheet, Charlie W. Lees, C Farrar, Christopher Prowse, Markku Laakso, David St Clair, Kate Downes, Diederick E. Grobbee, Paul Burton, Simon C. Potter, Ian N. Bruce, Tim D. Spector, Anne Barton, H.-Erich Wichmann, Matthew J. Simmonds, David Hadley, Cecilia M. Lindgren, Gérard Waeber, Nigel W. Rayner, Melanie J. Newport, Manjinder S. Sandhu, Audrey Duncanson, Guangju Zhai, Simon Heath, Susan M. Ring, Alessandra Di Gregorio, Richard Williamson, Nicholas J. Wareham, Zhan Su, Olle Melander, John R. Thompson, Alexander Teumer, Sheila A. Fisher, Lachlan J. M. Coin, Leif Groop, Giovanni Tognoni, Amanda Elkin, Alan J. Silman, Jack Satsangi, Jane Worthington, Martin Farrall, John Webster, Niall Cardin, Neil Walker, Anna F. Dominiczak, Jeremy D. Sanderson, Damjan Vukcevic, Bryan Howie, Silvia Polidoro, Stephen G. Ball, Mark Tremelling, Stephen Newhouse, Stephen M. Schwartz, Lori L. Bonnycastle, Chris Wallace, Kijoung Song, Mario A. Morken, I. Nicol Ferrier, Beverley Barke, Paolo Vineis, Manuela Uda, Deborah P M Symmons, Emily J. Lyons, Mingzhan Xue, Timothy M. Frayling, Stephen C.L. Cough, David Withers, Adrian V. S. Hill, Suzanne Stevens, Jennifer Jolley, Marcus Dörr, Kirk A. Rockett, David B. Dunger, Mark Walker, Jayne A. Franklyn, Lisa Jones, David S. Siscovick, Ann-Christine Syvänen, Laura J. Scott, Morris J. Brown, Barbera Cant, Michael Inouye, Feng Zhang, Carlotta Sacerdote, Katherine S. Elliott, Jonathan Marchini, Peter Donnely, Michael John Owen, An Goris, Marcus Prembey, Andrew T. Hattersley, Gerome Breen, Marian L. Hamshere, Thomas Illig, Samer S. Najjar, Nicole Soranzo, Kay-Tee Khaw, Graham R. Walters, Willem H. Ouwehand, David P. Strachan, Martin D. Tobin, Alastair Compston, John C. Mansfield, David Altshuler, Salvatore Panico, Sekar Kathiresan, Dawn M. Waterworth, Michael N. Weedon, D. Timothy Bishop, Claire Bryan, Alexandra S. Knight, Kate L. Lee, Paul F. O'Reilly, Massimo Mangino, Michael Conlon O'Donovan, Jing Hua Zhao, Konstantinos A. Papadakis, Jennifer H. Barrett, Joanne Pereira-Gale, N J Timpson, Stephan B. Felix, Panos Deloukas, Nicholas A. Watkins, Anna-Liisa Hartikainen, Peter Vollenweider, Richard Jones, Anne Hinks, Fraser Cummings, Noha Lim, Linda A. Bradbury, Rhian G. William, Nita G. Forouhi, Roberto Eluosa, Ingeleif B. Hallgrimsdottir, Giorgio Sirugo, Robert Luben, Veikko Salomaa, Robert Clarke, Sally John, Ursula Everson, Emma King, Ivan Nikolov, Heather M. Stringham, Antony P. Attwood, Angelo Scuteri
Publikováno v:
Nature Genetics, vol. 41, no. 6, pp. 666-676
Nature Genetics; Vol 41
Nature Genetics, 41(6), 666-676. Nature Publishing Group
Nature Genetics, 41, 666. Nature Publishing Group
Newton-Cheh, C, Johnson, T, Gateva, V, Tobin, M D, Bochud, M, Coin, L, Najjar, S S, Zhao, J H, Heath, S C, Eyheramendy, S, Papadakis, K, Voight, B F, Scott, L J, Zhang, F, Farrall, M, Tanaka, T, Wallace, C, Chambers, J C, Khaw, K-T, Nilsson, P, van der Harst, P, Polidoro, S, Grobbee, D E, Onland-Moret, N C, Bots, M L, Wain, L V, Elliott, K S, Teumer, A, Luan, J, Lucas, G, Kuusisto, J, Burton, P R, Hadley, D, McArdle, W L, Brown, M, Dominiczak, A, Newhouse, S J, Samani, N J, Webster, J, Zeggini, E, Beckmann, J S, Bergmann, S, Lim, N, Song, K, Vollenweider, P, Waeber, G, Waterworth, D M, Yuan, X & Groop, L & Orho-Melander, M 2009, ' Genome-wide association study identifies eight loci associated with blood pressure ', Nature Genetics, vol. 41, no. 6, pp. 666-76 . https://doi.org/10.1038/ng.361
Nature genetics
Nature Genetics
Nature Genetics; Vol 41
Nature Genetics, 41(6), 666-676. Nature Publishing Group
Nature Genetics, 41, 666. Nature Publishing Group
Newton-Cheh, C, Johnson, T, Gateva, V, Tobin, M D, Bochud, M, Coin, L, Najjar, S S, Zhao, J H, Heath, S C, Eyheramendy, S, Papadakis, K, Voight, B F, Scott, L J, Zhang, F, Farrall, M, Tanaka, T, Wallace, C, Chambers, J C, Khaw, K-T, Nilsson, P, van der Harst, P, Polidoro, S, Grobbee, D E, Onland-Moret, N C, Bots, M L, Wain, L V, Elliott, K S, Teumer, A, Luan, J, Lucas, G, Kuusisto, J, Burton, P R, Hadley, D, McArdle, W L, Brown, M, Dominiczak, A, Newhouse, S J, Samani, N J, Webster, J, Zeggini, E, Beckmann, J S, Bergmann, S, Lim, N, Song, K, Vollenweider, P, Waeber, G, Waterworth, D M, Yuan, X & Groop, L & Orho-Melander, M 2009, ' Genome-wide association study identifies eight loci associated with blood pressure ', Nature Genetics, vol. 41, no. 6, pp. 666-76 . https://doi.org/10.1038/ng.361
Nature genetics
Nature Genetics
Elevated blood pressure is a common, heritable cause of cardiovascular disease worldwide. To date, identification of common genetic variants influencing blood pressure has proven challenging. We tested 2.5 million genotyped and imputed SNPs for assoc
Autor:
Jane M. Carlton, Emily J. Lyons
Publikováno v:
Trends in Parasitology. 20:204-207
As is often the case in the study of infectious diseases, there are those interested in the basic biology of the organism and those primarily concerned with the clinical aspects of infection, disease and treatment. Although it is not uncommon for the
Publikováno v:
World Archaeology. 35:180-192
Historical texts provide credible evidence regarding the occurrence of malaria in recent human history but how far this antiquity stretches back through our hominid ancestors is questionable. Genetic analysis of the Plasmodium falciparum genome seque
Publikováno v:
Evolution. 52:1482-1486
Synergism among mutations can lead to an advantage to sexual reproduction, provided mutation rates are high enough (the mutational deterministic hypothesis). Here we tested the idea that competition for food can increase the advantage to sexual repro
Autor:
Maria D. Van Kerkhove, Jamie T. Griffin, Emily J. Lyons, Lulla Opatowski, Christophe Fraser, Neil M. Ferguson, Simon Cauchemez, Eric de Silva
Publikováno v:
PLoS Pathogens, Vol 7, Iss 9, p e1002225 (2011)
BASE-Bielefeld Academic Search Engine
PLoS Pathogens
BASE-Bielefeld Academic Search Engine
PLoS Pathogens
While in Northern hemisphere countries, the pandemic H1N1 virus (H1N1pdm) was introduced outside of the typical influenza season, Southern hemisphere countries experienced a single wave of transmission during their 2009 winter season. This provides a