Self-collection of capillary blood using Tasso-SST devices for Anti-SARS-CoV-2 IgG antibody testing.

Autor: Tess Hendelman, Anu Chaudhary, Angela C LeClair, Kimberly van Leuven, Jacqueline Chee, Susan L Fink, Emily J Welch, Erwin Berthier, Brook A Quist, Anna Wald, Mark H Wener, Andrew N Hoofnagle, Chihiro Morishima

Publikováno v: PLoS ONE, Vol 16, Iss 9, p e0255841 (2021)

BackgroundEfforts to minimize COVID-19 exposure during the current SARS-CoV-2 pandemic have led to limitations in access to medical care and testing. The Tasso-SST kit includes all of the components necessary for remote, capillary blood self-collecti

Externí odkaz: https://doaj.org/article/e2425dcf493c44129f94341902a0ea55

OCT‐based angiography of human dermal microvascular reactions to local stimuli: Implications for increasing capillary blood collection volumes

Autor: Shaozhen Song, Aarthi Ravichander, Jingjiang Xu, Jennifer Manyu Wong, Benjamin P. Casavant, Ruikang K. Wang, Shaojie Men, Erwin Berthier, Anthony J. Deegan, Emily J. Welch

Publikováno v: Lasers in Surgery and Medicine. 50:908-916

OBJECTIVES To measure and compare microvascular responses within the skin of the upper arm to local stimuli, such as heating or rubbing, through the use of optical coherence tomography angiography (OCTA), and to investigate its impact on blood volume

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6ff8f032fa4ab0644941e87b7392445
https://doi.org/10.1002/lsm.22944

Erythrocyte scaffolding protein p55/MPP1 functions as an essential regulator of neutrophil polarity

Autor: Anthony C. Kim, Anwar A. Khan, Anna Huttenlocher, Shafi M. Kuchay, Emily J. Welch, Brendan J. Quinn, Mary A. Lokuta, Athar H. Chishti

Publikováno v: Proceedings of the National Academy of Sciences. 106:19842-19847

As mediators of innate immunity, neutrophils respond to chemoattractants by adopting a highly polarized morphology. Efficient chemotaxis requires the formation of one prominent pseudopod at the cell front characterized by actin polymerization, while

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bee3109856d5966aa0dbe5d9e98ccabc
https://doi.org/10.1073/pnas.0906761106

Opposing Effects of Platelet-Activating Factor and Lyso-Platelet-Activating Factor on Neutrophil and Platelet Activation

Autor: Satoshi Ishii, Takao Shimizu, Ram P. Naikawadi, Phoebe Lin, Richard D. Ye, Chinnaswamy Tiruppathi, Emily J. Welch, Zhenyu Li, Papasani V. Subbaiah, Xiaoping Du

Publikováno v: Molecular Pharmacology. 75:227-234

Platelet-activating factor (PAF) is a potent, bioactive phospholipid that acts on multiple cells and tissues through its G protein-coupled receptor (GPCR). PAF is not stored but is rapidly generated via enzymatic acetylation of the precursor 1-O-hexa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9856449a22363d20b27283263a36adb9
https://doi.org/10.1124/mol.108.051003

A critical role for Lyn kinase in strengthening endothelial integrity and barrier function

Autor: Zhenyu Li, Jian Fu, Jingyan Han, Guoying Zhang, Emily J. Welch, Ying Liang, Asrar B. Malik, David A. Cheresh, Xiaoping Du, Stephen M. Vogel, Clifford A. Lowell

Publikováno v: Blood, vol 122, iss 25
Han, Jingyan; Zhang, Guoying; Welch, Emily J; Liang, Ying; Fu, Jian; Vogel, Stephen M; et al.(2013). A critical role for Lyn kinase in strengthening endothelial integrity and barrier function.. Blood, 122(25), 4140-4149. doi: 10.1182/blood-2013-03-491423. UC Office of the President: Research Grants Program Office (RGPO). Retrieved from: http://www.escholarship.org/uc/item/3vb8j9xf

The Src family kinases (SFKs) c-Src and Yes mediate vascular leakage in response to various stimuli including lipopolysaccharide (LPS) and vascular endothelial growth factor (VEGF). Here, we define an opposing function of another SFK, Lyn, which in c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86e55e5b91f202fe861053cb4f0adb80
https://escholarship.org/uc/item/3vb8j9xf