Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Emily J Tsai"'
Autor:
Michael I. Brener, Michelle L. Hulke, Nobuaki Fukuma, Stephanie Golob, Robert S. Zilinyi, Zhipeng Zhou, Christos Tzimas, Ilaria Russo, Claire McGroder, Ryan D. Pfeiffer, Alexander Chong, Geping Zhang, Daniel Burkhoff, Martin B. Leon, Mathew S. Maurer, Jeffrey W. Moses, Anne-Catrin Uhlemann, Hanina Hibshoosh, Nir Uriel, Matthias J. Szabolcs, Björn Redfors, Charles C. Marboe, Matthew R. Baldwin, Nathan R. Tucker, Emily J. Tsai
Publikováno v:
JCI Insight, Vol 7, Iss 2 (2022)
Acute cardiac injury is prevalent in critical COVID-19 and associated with increased mortality. Its etiology remains debated, as initially presumed causes — myocarditis and cardiac necrosis — have proved uncommon. To elucidate the pathophysiology
Externí odkaz:
https://doaj.org/article/2de2e76911bc473598fb90fee54b07f0
Publikováno v:
Circulation Research. 132:1290-1301
From the onset of the pandemic, evidence of cardiac involvement in acute COVID-19 abounded. Cardiac presentations ranged from arrhythmias to ischemia, myopericarditis/myocarditis, ventricular dysfunction to acute heart failure, and even cardiogenic s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a54bccef2216b805333dd35b60e8c314
https://doi.org/10.1161/circresaha.123.321876
https://doi.org/10.1161/circresaha.123.321876
Publikováno v:
Current Cardiology Reports. 25:171-184
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac45857c42440c84098169a13bd1e46d
https://doi.org/10.1007/s11886-023-01841-6
https://doi.org/10.1007/s11886-023-01841-6
Autor:
Arianne Papa, Sergey I. Zakharov, Alexander N. Katchman, Jared S. Kushner, Bi-xing Chen, Lin Yang, Guoxia Liu, Alejandro Sanchez Jimenez, Robyn J. Eisert, Gary A. Bradshaw, Wen Dun, Shah R. Ali, Aaron Rodriques, Karen Zhou, Veli Topkara, Mu Yang, John P. Morrow, Emily J. Tsai, Arthur Karlin, Elaine Wan, Marian Kalocsay, Geoffrey S. Pitt, Henry M. Colecraft, Manu Ben-Johny, Steven O. Marx
Publikováno v:
Nature Cardiovascular Research. 1:1022-1038
Fight-or-flight responses involve β-adrenergic-induced increases in heart rate and contractile force. In the present study, we uncover the primary mechanism underlying the heart’s innate contractile reserve. We show that four protein kinase A (PKA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d29a7152c7195aa5159ea1ac39befef0
https://doi.org/10.1038/s44161-022-00157-y
https://doi.org/10.1038/s44161-022-00157-y
Autor:
Arianne, Papa, Sergey I, Zakharov, Alexander N, Katchman, Jared S, Kushner, Bi-Xing, Chen, Lin, Yang, Guoxia, Liu, Alejandro Sanchez, Jimenez, Robyn J, Eisert, Gary A, Bradshaw, Wen, Dun, Shah R, Ali, Aaron, Rodriques, Karen, Zhou, Veli, Topkara, Mu, Yang, John P, Morrow, Emily J, Tsai, Arthur, Karlin, Elaine, Wan, Marian, Kalocsay, Geoffrey S, Pitt, Henry M, Colecraft, Manu, Ben-Johny, Steven O, Marx
Publikováno v:
Nature cardiovascular research. 1(11)
Fight-or-flight responses involve β-adrenergic-induced increases in heart rate and contractile force. In the present study, we uncover the primary mechanism underlying the heart's innate contractile reserve. We show that four protein kinase A (PKA)-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::098eb2ff6d51588c62d0ba69760229f2
https://pubmed.ncbi.nlm.nih.gov/36424916
https://pubmed.ncbi.nlm.nih.gov/36424916
Autor:
Andrew Peters, Mara Caroline, Huaqing Zhao, Matthew R. Baldwin, Paul R. Forfia, Emily J. Tsai
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 9 (2018)
BackgroundOutcomes in peripartum cardiomyopathy (PPCM) vary. We sought to determine whether severity of left or right ventricular dysfunction (RVD) at PPCM diagnosis differentially associates with adverse outcomes. Methods and ResultsWe conducted a s
Externí odkaz:
https://doaj.org/article/1484a708d04b43639bbdfb833e1addf5
Autor:
Jay H. Lefkowitch, Samuel F. Bakhoum, George A. Alba, Denis Schapiro, Yaron Bram, Patricia Ho, Ajay Nair, Anjali Saqi, Yiping Wang, Robert E. Schwartz, Daniel T. Montoro, Armando Del Portillo, Jianwen Que, Alain C. Borczuk, Robert F. Schwabe, Sean W. Chen, André F. Rendeiro, Johannes C. Melms, Somnath Tagore, Hanina Hibshoosh, Adrienne M. Luoma, Adam E. Kornberg, Amit Dipak Amin, Mariano G. Clausi, Niroshana Anandasabapathy, Chris J. Frangieh, Stephen M. Lagana, Olivier Elemento, Yinshan Fang, Huachao Huang, Igor Katsyv, Mayte Suárez-Fariñas, Xinzheng V. Guo, Benjamin Izar, Emily J. Tsai, Charles C. Marboe, Mathieu F. Bakhoum, Aveline Filliol, Glen S. Markowitz, Hiranmayi Ravichandran, Arnold Han, Emmanuel Zorn, Meri Rogava, Jana Biermann
Publikováno v:
Nature. 595:114-119
Respiratory failure is the leading cause of death in patients with severe SARS-CoV-2 infection1,2, but the host response at the lung tissue level is poorly understood. Here we performed single-nucleus RNA sequencing of about 116,000 nuclei from the l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cefac8d5d3925263c7f2ffbb4292f5c1
https://doi.org/10.1038/s41586-021-03569-1
https://doi.org/10.1038/s41586-021-03569-1
Autor:
Tamanna Singh, John C. Tilton, Joseph Loscalzo, John Barnard, Emily J. Tsai, Scott J. Cameron, Mina K. Chung, Deborah H. Kwon, David A. Zidar, Nathan R. Tucker, Timothy A. Chan, Clifford V. Harding, Michael R. Bristow
Publikováno v:
Circulation Research. 128:1214-1236
A pandemic of historic impact, coronavirus disease 2019 (COVID-19) has potential consequences on the cardiovascular health of millions of people who survive infection worldwide. Severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2), the etiolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::379d79f37dd0cc7a27901bb930377ad0
https://doi.org/10.1161/circresaha.121.317997
https://doi.org/10.1161/circresaha.121.317997
Autor:
Robert Zilinyi, Emily J. Tsai, Alexander M. Chong, Nathan R. Tucker, Nobuaki Fukuma, Anne-Catrin Uhlemann, Zhipeng Zhou, Ryan D Pfeiffer, Matthias Szabolcs, Mathew S. Maurer, Christos Tzimas, Martin B. Leon, Michelle L Hulke, Geping Zhang, Stephanie Golob, Nir Uriel, Matthew R. Baldwin, Claire McGroder, Charles C. Marboe, Ilaria Russo, Michael I. Brener, Jeffrey W. Moses, Björn Redfors, Daniel Burkhoff, Hanina Hibshoosh
Cardiac injury is associated with critical COVID-19, yet its etiology remains debated. To elucidate the pathogenic mechanisms of COVID-19-associated cardiac injury, we conducted a single-center prospective cohort study of 69 COVID-19 decedents. Of si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e21254c634de7a6a493127b8ec834fb3
https://doi.org/10.1101/2021.07.27.453843
https://doi.org/10.1101/2021.07.27.453843
Autor:
Matthew Bacchetta, Emily J. Tsai, Keith Cook, Erika B. Rosenzweig, Caitlin T. Demarest, Clayne Benson, Yatrik Patel, Nancy Cardwell, Jennifer Talackine, W. Kelly Wu, John W. Stokes, Rei Ukita
Publikováno v:
Journal of Visualized Experiments.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aacaed89972b7609aec189ec95936753
https://doi.org/10.3791/62694-v
https://doi.org/10.3791/62694-v