Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Emily J Sherman"'
Autor:
Emily J Sherman, Carmen Mirabelli, Vi T Tang, Taslima G Khan, Kyle Leix, Andrew A Kennedy, Sarah E Graham, Cristen J Willer, Andrew W Tai, Jonathan Z Sexton, Christiane E Wobus, Brian T Emmer
Publikováno v:
PLoS Pathogens, Vol 18, Iss 3, p e1010377 (2022)
SARS-CoV-2 infection is initiated by binding of the viral spike protein to its receptor, ACE2, on the surface of host cells. ACE2 expression is heterogeneous both in vivo and in immortalized cell lines, but the molecular pathways that govern ACE2 exp
Externí odkaz:
https://doaj.org/article/acccdef33b934d528edc14fc2c53eec4
Autor:
Brian T Emmer, Emily J Sherman, Paul J Lascuna, Sarah E Graham, Cristen J Willer, David Ginsburg
Publikováno v:
PLoS Genetics, Vol 17, Iss 1, p e1009285 (2021)
Hypercholesterolemia is a causal and modifiable risk factor for atherosclerotic cardiovascular disease. A critical pathway regulating cholesterol homeostasis involves the receptor-mediated endocytosis of low-density lipoproteins into hepatocytes, med
Externí odkaz:
https://doaj.org/article/b69d1bece3cb4a27a991ea55effe4e85
Autor:
Juliana Bragazzi Cunha, Kyle Leix, Emily J. Sherman, Carmen Mirabelli, Andrew A. Kennedy, Adam S. Lauring, Andrew W. Tai, Christiane E. Wobus, Brian T. Emmer
Disease progression during SARS-CoV-2 infection is tightly linked to the fate of lung epithelial cells, with severe cases of COVID-19 characterized by direct injury of the alveolar epithelium and an impairment in its regeneration from progenitor cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d9bc51020fb224f2bd7b3a68f43a6c0
https://doi.org/10.1101/2023.02.28.530557
https://doi.org/10.1101/2023.02.28.530557
Publikováno v:
Journal of Biological Chemistry. 294:17188-17196
MicroRNAs (miRNAs or miRs) are small, noncoding RNAs that are implicated in the regulation of most biological processes. Global miRNA biogenesis is altered in many cancers, and RNA-binding proteins play a role in miRNA biogenesis, presenting a promis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5bb005b292e0d201ed0902d922e6b823
https://doi.org/10.1074/jbc.ac119.010419
https://doi.org/10.1074/jbc.ac119.010419
Publikováno v:
ACS Combinatorial Science. 21:522-527
Click chemistry-based assays are a growing class of biochemical assay for facilitating the discovery of modulators of important biological processes. To date, most have relied on the use of immobilized biomolecules, which increases the cost of the as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fcd6518a23aa813e8d85af165c6f411
https://doi.org/10.1021/acscombsci.9b00071
https://doi.org/10.1021/acscombsci.9b00071
Autor:
Wenzhao Meng, Carmen Mirabeli, Aaron M. Rosenfeld, Mayara Garcia de Mattos Barbosa, Greg Shelley, Emily J. Sherman, Milagros Samaniego, Thomas M. Lanigan, Daniel Huynh, Evan T. Keller, Andrew W. Tai, Christiane E. Wobus, Eline T. Luning Prak, Hui Liu, Marilia Cascalho, Andrew A Kennedy, Brian T. Emmer, Jeffrey L. Platt, David Ginsburg
Publikováno v:
JCI Insight, Vol 6, Iss 9 (2021)
JCI Insight
JCI Insight
Abs that neutralize SARS-CoV-2 are thought to provide the most immediate and effective treatment for those severely afflicted by this virus. Because coronavirus potentially diversifies by mutation, broadly neutralizing Abs are especially sought. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0ec369ff6ab5200094ffb8be471a405
https://doaj.org/article/198aea9cddb24432ade981042f42b068
https://doaj.org/article/198aea9cddb24432ade981042f42b068
Autor:
Emily J. Sherman, Brian T. Emmer
Publikováno v:
bioRxiv
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
The membrane protein angiotensin-converting enzyme 2 (ACE2) is a physiologic regulator of the renin-angiotensin system and the cellular receptor for the SARS-CoV-2 virus. Prior studies of ACE2 expression have primarily focused on mRNA abundance, with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a20d0f15f786785757f8209a1674277
https://doi.org/10.1101/2021.03.26.437218
https://doi.org/10.1101/2021.03.26.437218
Autor:
David Ginsburg, Emily J. Sherman, Sarah E. Graham, Cristen J. Willer, Brian T. Emmer, Paul J. Lascuna
Hypercholesterolemia is a causal and modifiable risk factor for atherosclerotic cardiovascular disease. A critical pathway regulating cholesterol homeostasis involves the receptor-mediated endocytosis of low-density lipoproteins into hepatocytes, med
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5606e0664417bc3adeba912f659be1c8
https://doi.org/10.1101/2020.07.01.182246
https://doi.org/10.1101/2020.07.01.182246
Autor:
Paul J. Lascuna, Emily J. Sherman, David Ginsburg, Brian T. Emmer, Cristen J. Willer, Sarah E. Graham
Publikováno v:
PLoS Genetics, Vol 17, Iss 1, p e1009285 (2021)
PLoS Genetics
PLoS Genetics
Hypercholesterolemia is a causal and modifiable risk factor for atherosclerotic cardiovascular disease. A critical pathway regulating cholesterol homeostasis involves the receptor-mediated endocytosis of low-density lipoproteins into hepatocytes, med
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7b3a1371ee21f47b55b9d859e56b5b2
https://doi.org/10.1371/journal.pgen.1009285
https://doi.org/10.1371/journal.pgen.1009285
Autor:
Robert C. Wilson, Emily J. Sherman
Dopamine has long been thought to play a role in risky decision-making, with higher tonic levels of dopamine associated with more risk seeking behavior. In this work, we aimed to shed more light on this relationship using spontaneous blink rate as an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3856851054f8bd8630ca194a3dae22c3
https://doi.org/10.1101/046821
https://doi.org/10.1101/046821