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pro vyhledávání: '"Emily Isabella Moffat"'
Autor:
Jung Min Song, Emily Isabella Moffat, You Me Sung, Daniel T.S. Pak, Andrew Chung, Hyang Sook Hoe, Hyejin Yoon, Jin Han Nam, Jungsu Kim, Mira Jung
Publikováno v:
Journal of Alzheimer's Disease. 51:591-604
Background: The accumulation of amyloid- (A) leads to the loss of dendritic spines and synapses, which is hypothesized to cause cognitive impairments in Alzheimer’s disease (AD) patients. In our previous study, we demonstrated that a novel mercapto
Autor:
R. Scott Turner, Hyang Sook Hoe, Jungsu Kim, Mira Jung, Jung Min Song, Hyejin Yoon, Emily Isabella Moffat, You Me Sung, Amanda M. DiBattista, Yoojin Sohn, Taehee Lee
Publikováno v:
Experimental neurology. 239
Histone deacetylase inhibitors (HDACIs) alter gene expression epigenetically by interfering with the normal functions of HDAC. Given their ability to decrease Aβ levels, HDACIs are a potential treatment for Alzheimer's disease (AD). However, it is u