Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Emily I. Chen"'
Autor:
Alexandre Ribault, Mohamed Amine Benadjaoud, Claire Squiban, Laurent Arnaud, Coralie Judicone, Aurélie S. Leroyer, Alexandra Rousseau, Christelle Huet, Chandan Guha, Marc Benderitter, Romaric Lacroix, Stephane Flamant, Emily I. Chen, Jean-Marc Simon, Radia Tamarat
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract In a large retrospective study, we assessed the putative use of circulating microvesicles (MVs), as innovative biomarkers of radiation toxicity in a cohort of 208 patients with prostate adenocarcinoma overexposed to radiation. The level of p
Externí odkaz:
https://doaj.org/article/74a0e092cc38444aa0ec420a2040ca5a
Autor:
Hidetoshi Mori, Ramray Bhat, Alexandre Bruni-Cardoso, Emily I. Chen, Danielle M. Jorgens, Kester Coutinho, Katherine Louie, Benjamin Ben Bowen, Jamie L. Inman, Victoria Tecca, Sarah J. Lee, Sabine Becker-Weimann, Trent Northen, Motoharu Seiki, Alexander D. Borowsky, Manfred Auer, Mina J. Bissell
Publikováno v:
PeerJ, Vol 4, p e2142 (2016)
Membrane-anchored matrix metalloproteinase 14 (MMP14) is involved broadly in organ development through both its proteolytic and signal-transducing functions. Knockout of Mmp14 (KO) in mice results in a dramatic reduction of body size and wasting foll
Externí odkaz:
https://doaj.org/article/6bb34109530b4eebac8d02e398df41f0
Autor:
Paul J. Planet, Dane Parker, Taylor S. Cohen, Hannah Smith, Justinne D. Leon, Chanelle Ryan, Tobin J. Hammer, Noah Fierer, Emily I. Chen, Alice S. Prince
Publikováno v:
mBio, Vol 7, Iss 1 (2016)
ABSTRACT Much of the morbidity and mortality associated with influenza virus respiratory infection is due to bacterial coinfection with pathogens that colonize the upper respiratory tract such as methicillin-resistant Staphylococcus aureus (MRSA) and
Externí odkaz:
https://doaj.org/article/49787d6a198d4200bd7c5c8ac7398470
Data from Precision Targeting with EZH2 and HDAC Inhibitors in Epigenetically Dysregulated Lymphomas
Autor:
Jennifer E. Amengual, Olivier Elemento, Neil L. Kelleher, Serge Cremers, Renu Nandakumar, Changhong Qiao, Emily I. Chen, Swasti Mehta, Jeannie M. Camarillo, Nebiyu Abshiru, Prabhjot S. Mundi, Akanksha Verma, Yulissa Gonzalez, Yuxuan Liu, Sathyen A. Prabhu, Jennifer K. Lue
Purpose:Both gain-of-function enhancer of zeste homolog 2 (EZH2) mutations and inactivating histone acetyltransferases mutations, such as CREBBP and EP300, have been implicated in the pathogenesis of germinal center (GC)–derived lymphomas. We hypot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46c25494f751d349c18a9a0f314e919e
https://doi.org/10.1158/1078-0432.c.6527655
https://doi.org/10.1158/1078-0432.c.6527655
Autor:
Jennifer E. Amengual, Olivier Elemento, Neil L. Kelleher, Serge Cremers, Renu Nandakumar, Changhong Qiao, Emily I. Chen, Swasti Mehta, Jeannie M. Camarillo, Nebiyu Abshiru, Prabhjot S. Mundi, Akanksha Verma, Yulissa Gonzalez, Yuxuan Liu, Sathyen A. Prabhu, Jennifer K. Lue
Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a3a7acc7afb6706436cb46f252d3e0a
https://doi.org/10.1158/1078-0432.22470681
https://doi.org/10.1158/1078-0432.22470681
Autor:
Wei-Xing Zong, Jianhua Zhang, Howard C. Crawford, Song Wu, Ji-An Pan, Emily I. Chen, Erica Ullman, Yu Sun, Alex J. Bott, Joseph M. Catanzaro, Namratha Sheshadri
Supplemental Materials and Methods, Figure Legend, Figures S1-6. Figure S1. SCCA1-expressing MCF10A cells become independent of the hormonal factors. Figure S2. Expression of SCCA1 leads to IL-6 production. Figure S3. The induction of UPR by SCCA1 is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4945a11a19c0d30e9e5867686ef8b982
https://doi.org/10.1158/0008-5472.22403801
https://doi.org/10.1158/0008-5472.22403801
Autor:
Turhan Canli, Lei Yu, Magdalena Jurkiewicz, Dirk Alexander Moser, Emily I. Chen, Antonius Koller, David A. Bennett
Publikováno v:
Translational Psychiatry, Vol 10, Iss 1, Pp 1-10 (2020)
Translational Psychiatry
Translational Psychiatry
Recent genome-wide studies have begun to identify gene variants, expression profiles, and regulators associated with neuroticism, anxiety disorders, and depression. We conducted a set of experimental cell culture studies of gene regulation by micro R
Autor:
Seiya Kitamura, Qinheng Zheng, Nicholas Dillon, Angelo Solania, Jordan L. Woehl, Miyako Kotaniguchi, John R. Cappiello, Shinichi Kitamura, Dennis W. Wolan, Victor Nizet, Mitchell V. Hull, Emily I. Chen, K. Barry Sharpless
Publikováno v:
J Am Chem Soc
Optimization of small-molecule probes or drugs is a synthetically lengthy, challenging, and resource-intensive process. Lack of automation and reliance on skilled medicinal chemists is cumbersome in both academic and industrial settings. Here, we dem
Autor:
Daniel P. Kelly, Rick B. Vega, Emily I. Chen, Gongxin Yu, Michael A. Kiebish, Vladimir Tolstikov, Bret H. Goodpaster, Niven R. Narain, Michelle B. Trevino, Gramoz Kondakci, Robert A. Standley, Giovanna Distefano, Paul M. Coen, Feng Qi, Bennett Greenwood
Publikováno v:
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences
Background Older adults exposed to periods of inactivity during hospitalization, illness, or injury lose muscle mass and strength. This, in turn, predisposes poor recovery of physical function upon reambulation and represents a significant health ris
Autor:
Emily I. Chen, Gretchen M. Ehrenkaufer, Monica M. Kangussu-Marcolino, Upinder Singh, Anjan Debnath
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 11, Iss, Pp 80-94 (2019)
International Journal for Parasitology: Drugs and Drug Resistance
International Journal for Parasitology: Drugs and Drug Resistance
The free-living amebae Naegleria, Acanthamoeba, and Balamuthia cause rare but life-threatening infections. All three parasites can cause meningoencephalitis. Acanthamoeba can also cause chronic keratitis and both Balamuthia and Acanthamoeba can cause