Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Emily Hulsey"'
Autor:
Silpa Gampala, Fenil Shah, Xiaoyu Lu, Hye-ran Moon, Olivia Babb, Nikkitha Umesh Ganesh, George Sandusky, Emily Hulsey, Lee Armstrong, Amber L. Mosely, Bumsoo Han, Mircea Ivan, Jing-Ruey Joanna Yeh, Mark R. Kelley, Chi Zhang, Melissa L. Fishel
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-24 (2021)
Abstract Background Pancreatic cancer is a complex disease with a desmoplastic stroma, extreme hypoxia, and inherent resistance to therapy. Understanding the signaling and adaptive response of such an aggressive cancer is key to making advances in th
Externí odkaz:
https://doaj.org/article/751a9e3c189b45859ea1d97745ceb7f8
Autor:
Aditi S. Khatpe, Rebecca Dirks, Poornima Bhat-Nakshatri, Henry Mang, Katie Batic, Sarah Swiezy, Jacob Olson, Xi Rao, Yue Wang, Hiromi Tanaka, Sheng Liu, Jun Wan, Duojiao Chen, Yunlong Liu, Fang Fang, Sandra Althouse, Emily Hulsey, Maggie M. Granatir, Rebekah Addison, Constance J. Temm, George Sandusky, Audrey Lee-Gosselin, Kenneth Nephew, Kathy D. Miller, Harikrishna Nakshatri
Publikováno v:
Cancer Research. 83:1345-1360
Study of genomic aberrations leading to immortalization of epithelial cells has been technically challenging due to the lack of isogenic models. To address this, we used healthy primary breast luminal epithelial cells of different genetic ancestry an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d80bdbe8f7e3fd859b87ba6cb6728f30
https://doi.org/10.1158/0008-5472.can-22-3667
https://doi.org/10.1158/0008-5472.can-22-3667
Autor:
Harikrishna Nakshatri, Kathy D. Miller, Kenneth Nephew, Audrey Lee-Gosselin, George Sandusky, Constance J. Temm, Rebekah Addison, Maggie M. Granatir, Emily Hulsey, Sandra Althouse, Fang Fang, Yunlong Liu, Duojiao Chen, Jun Wan, Sheng Liu, Hiromi Tanaka, Yue Wang, Xi Rao, Jacob Olson, Sarah Swiezy, Katie Batic, Henry Mang, Poornima Bhat-Nakshatri, Rebecca Dirks, Aditi S. Khatpe
Table S9: Results of ATAC-seq of primary and TONSL-immortalized cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aebc890399e5bfe96f54d95a43428de
https://doi.org/10.1158/0008-5472.22633261.v1
https://doi.org/10.1158/0008-5472.22633261.v1
Autor:
Harikrishna Nakshatri, Kathy D. Miller, Kenneth Nephew, Audrey Lee-Gosselin, George Sandusky, Constance J. Temm, Rebekah Addison, Maggie M. Granatir, Emily Hulsey, Sandra Althouse, Fang Fang, Yunlong Liu, Duojiao Chen, Jun Wan, Sheng Liu, Hiromi Tanaka, Yue Wang, Xi Rao, Jacob Olson, Sarah Swiezy, Katie Batic, Henry Mang, Poornima Bhat-Nakshatri, Rebecca Dirks, Aditi S. Khatpe
Study of genomic aberrations leading to immortalization of epithelial cells has been technically challenging due to the lack of isogenic models. To address this, we used healthy primary breast luminal epithelial cells of different genetic ancestry an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a02b10f9fff51b50bf5355116b3f214
https://doi.org/10.1158/0008-5472.c.6599674.v1
https://doi.org/10.1158/0008-5472.c.6599674.v1
Supplementary Data from TONSL Is an Immortalizing Oncogene and a Therapeutic Target in Breast Cancer
Autor:
Harikrishna Nakshatri, Kathy D. Miller, Kenneth Nephew, Audrey Lee-Gosselin, George Sandusky, Constance J. Temm, Rebekah Addison, Maggie M. Granatir, Emily Hulsey, Sandra Althouse, Fang Fang, Yunlong Liu, Duojiao Chen, Jun Wan, Sheng Liu, Hiromi Tanaka, Yue Wang, Xi Rao, Jacob Olson, Sarah Swiezy, Katie Batic, Henry Mang, Poornima Bhat-Nakshatri, Rebecca Dirks, Aditi S. Khatpe
Contains additional materials and methods and supplementary figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f5b3f2a2a751789590276560b96ae52
https://doi.org/10.1158/0008-5472.22633315
https://doi.org/10.1158/0008-5472.22633315
Autor:
Olivia Babb, Fenil Shah, Lee Armstrong, Emily Hulsey, Hye-ran Moon, Amber L Mosely, Melissa L. Fishel, Jing-Ruey Joanna Yeh, Mark R. Kelley, Silpa Gampala, George E. Sandusky, Bumsoo Han, Nikkitha Umesh Ganesh, Chi Zhang, Mircea Ivan, Xiaoyu Lu
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-24 (2021)
Journal of Experimental & Clinical Cancer Research : CR
Journal of Experimental & Clinical Cancer Research : CR
BackgroundPancreatic cancer is a complex disease with a desmoplastic stroma, extreme hypoxia, and inherent resistance to therapy. Understanding the signaling and adaptive response of such an aggressive cancer is key to making advances in therapeutic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59882bc64608b96a6c5400722434b880
https://doaj.org/article/751a9e3c189b45859ea1d97745ceb7f8
https://doaj.org/article/751a9e3c189b45859ea1d97745ceb7f8
Autor:
Yan Tong, Silpa Gampala, Ellie Rad, Ren Yuan Bai, Olivia Babb, Emily Hulsey, Fenil Shah, Chi Zhang, Steven D. Rhodes, Verena Staedtke, Randall Wireman, Brian L. Calver, Mark R. Kelley, Michelle Grimard, M. Reza Saadatzadeh, Abbi Smith, D. Wade Clapp, Andrew R. Tee, Karen E. Pollok, Melissa L. Fishel
Publikováno v:
British Journal of Cancer
Background MPNST is a rare soft-tissue sarcoma that can arise from patients with NF1. Existing chemotherapeutic and targeted agents have been unsuccessful in MPNST treatment, and recent findings implicate STAT3 and HIF1-α in driving MPNST. The DNA-b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec69838060868f6ccae17ccdf078f1f2
http://europepmc.org/articles/PMC8076291
http://europepmc.org/articles/PMC8076291
Autor:
Emily Hulsey, Olivia Babb, Silpa Gampala, Bumsoo Han, Rachel A. Caston, Randall Wireman, Hye-ran Moon, Andi R. Masters, James H. Wikel, Melissa L. Fishel, George E. Sandusky, Millie M. Georgiadis, Mark R. Kelley, Sara K. Quinney, Nayela N. Chowdhury
Publikováno v:
Cancer Research. 81:1452-1452
Targeted therapy for cancer using small molecules has progressed exponentially, but agents that can affect cancer cells rather than non-tumorigenic cells are crucial to avoid pernicious side effects. AP endonuclease-1/Redox factor-1 (APE1/Ref-1 or Re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f26d119d57c371c631e2636829c28ab
https://doi.org/10.1158/1538-7445.am2021-1452
https://doi.org/10.1158/1538-7445.am2021-1452
Autor:
Emily Hulsey, Fenil Shah, Hye-ran Moon, George E. Sandusky, Silpa Gampala, Bamsoo Han, Xiaoyu Lu, Melissa L. Fishel, Amber L. Mosley, Mark R. Kelley, Chi Zhang
Publikováno v:
Cancer Research. 81:PO025-PO025
Pancreatic cancer can survive under the harshest of conditions including nutrient deprivation and extreme hypoxia. Its complex microenvironment contributes to PDAC’s (pancreatic ductal adenocarcinoma) therapeutic resistance and aggressive metastasi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a616e9c29d5e5d67b1a9d058cfa80d85
https://doi.org/10.1158/1538-7445.tme21-po025
https://doi.org/10.1158/1538-7445.tme21-po025