Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Emily H-Y. Cheng"'
Autor:
Thirupura S. Shankar, Dinesh K. A. Ramadurai, Kira Steinhorst, Salah Sommakia, Rachit Badolia, Aspasia Thodou Krokidi, Dallen Calder, Sutip Navankasattusas, Paulina Sander, Oh Sung Kwon, Aishwarya Aravamudhan, Jing Ling, Andreas Dendorfer, Changmin Xie, Ohyun Kwon, Emily H. Y. Cheng, Kevin J. Whitehead, Thomas Gudermann, Russel S. Richardson, Frank B. Sachse, Johann Schredelseker, Kenneth W. Spitzer, Dipayan Chaudhuri, Stavros G. Drakos
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
The authors found that VDAC2 plays a crucial role in influencing mitochondrial calcium dynamics and cellular calcium signalling. A VDAC2 agonist, efsevin, rescued the heart failure phenotype, identifying a new potential therapeutic target for heart f
Externí odkaz:
https://doaj.org/article/5def0b8a41bf407088eed68a7df3942d
Autor:
James J-D. Hsieh, Emily H-Y. Cheng, Dongsi Lu, Brian A. Van Tine, Satoru Sasagawa, Ho-Chou Tu, Shugaku Takeda, Han Liu, David Y. Chen
Taspase1, the mixed lineage leukemia and TFIIAα-β cleaving protease, enables cell proliferation and permits oncogenic initiation. Here, we show its critical role in cancer maintenance and thus offer a new anticancer target. Taspase1 is overexpresse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::811fcf0adc78329665f1239670f1898f
https://doi.org/10.1158/0008-5472.c.6500150.v1
https://doi.org/10.1158/0008-5472.c.6500150.v1
Autor:
James J-D. Hsieh, Emily H-Y. Cheng, Dongsi Lu, Brian A. Van Tine, Satoru Sasagawa, Ho-Chou Tu, Shugaku Takeda, Han Liu, David Y. Chen
Supplementary Methods, Figures 1-11, Table 1 from Taspase1 Functions as a Non-Oncogene Addiction Protease that Coordinates Cancer Cell Proliferation and Apoptosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5522b38fb2f90e0fc0fc407bf08502e7
https://doi.org/10.1158/0008-5472.22382282.v1
https://doi.org/10.1158/0008-5472.22382282.v1
Autor:
James J.-D. Hsieh, Emily H.-Y. Cheng, Robert H. Shoemaker, Richard Gussio, Ann Hermone, Stanley J. Korsmeyer, Kyoung J. Oh, David R. Piwnica-Worms, Yiyu Dong, Shugaku Takeda, Ho-Chou Tu, Han Liu, Todd D. Westergard, Adam C. Searleman, Brian A. Van Tine, Yishan Lee, David Y. Chen
PDF file - 782K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cb2a0664daaaa691fd6952ffd4eef20
https://doi.org/10.1158/0008-5472.22392198.v1
https://doi.org/10.1158/0008-5472.22392198.v1
Autor:
Jason Karch, Jennifer Q Kwong, Adam R Burr, Michelle A Sargent, John W Elrod, Pablo M Peixoto, Sonia Martinez-Caballero, Hanna Osinska, Emily H-Y Cheng, Jeffrey Robbins, Kathleen W Kinnally, Jeffery D Molkentin
Publikováno v:
eLife, Vol 2 (2013)
A critical event in ischemia-based cell death is the opening of the mitochondrial permeability transition pore (MPTP). However, the molecular identity of the components of the MPTP remains unknown. Here, we determined that the Bcl-2 family members Ba
Externí odkaz:
https://doaj.org/article/05dd5d4356784fc28183de961bc98086
Autor:
Ignacio, Gonzalez-Suarez, Abena B, Redwood, David A, Grotsky, Martin A, Neumann, Emily H-Y, Cheng, Colin L, Stewart, Adriana, Dusso, Susana, Gonzalo
Publikováno v:
The EMBO journal. 30(16)
Genomic instability due to telomere dysfunction and defective repair of DNA double-strand breaks (DSBs) is an underlying cause of ageing-related diseases. 53BP1 is a key factor in DNA DSBs repair and its deficiency is associated with genomic instabil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::11f8e1c8b2877d41b37e895f547dff1b
https://pubmed.ncbi.nlm.nih.gov/21750527
https://pubmed.ncbi.nlm.nih.gov/21750527
Publikováno v:
Cell. 115(3)
The Mixed-Lineage Leukemia gene (MLL/HRX/ALL1) encodes a large nuclear protein homologous to Drosophila trithorax that is required for the maintenance of HOX gene expression. MLL is cleaved at two conserved sites generating N320 and C180 fragments, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::609b616f8651c28904a365364b8f2489
https://pubmed.ncbi.nlm.nih.gov/14636551
https://pubmed.ncbi.nlm.nih.gov/14636551
Autor:
Ishii, Yuki1,2, Nhiayi, May Keu1,2, Tse, Edison1,2, Cheng, Jonathan3, Massimino, Michele4, Durden, Donald L.2,5, Vigneri, Paolo4, Wang, Jean Y. J.1,2,3 jywang@ucsd.edu
Publikováno v:
PLoS ONE. 10/16/2015, Vol. 10 Issue 10, p1-24. 24p.
Publikováno v:
Cell Death & Differentiation. Feb2009, Vol. 16 Issue 2, p264-277. 14p. 3 Color Photographs, 1 Black and White Photograph, 4 Graphs.
Autor:
Cheng, Emily H.-Y., Sheiko, Tatiana V., Fisher, Jill K., Craigen, William J., Korsmeyer, Stanley J.
Publikováno v:
Science. 7/25/2003, Vol. 301 Issue 5632, p513-517. 5p. 2 Diagrams, 2 Graphs.