Rescue of mitochondrial import failure by intercellular organellar transfer

Autor: Hope I. Needs, Emily Glover, Gonçalo C. Pereira, Alina Witt, Wolfgang Hübner, Mark P. Dodding, Jeremy M. Henley, Ian Collinson

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)

Abstract Mitochondria are the powerhouses of eukaryotic cells, composed mostly of nuclear-encoded proteins imported from the cytosol. Thus, problems with the import machinery will disrupt their regenerative capacity and the cell’s energy supplies �

Externí odkaz: https://doaj.org/article/76241f22b7d343e9b3d616b1e3d7924b

Receiving a Diagnosis of Pernicious Anemia: Exploring Experiences of Relationships With Health Professionals

Autor: Catherine Heidi Seage PhD, Emily Glover MSc, Jenny Mercer PhD

Publikováno v: Journal of Patient Experience, Vol 7 (2020)

Objectives: Pernicious anemia (PA) is a chronic condition caused by vitamin B12 deficiency. This is a qualitative study using interpretative phenomenological analysis (IPA), which aimed to explore the patients lived experience of diagnosis and treatm

Externí odkaz: https://doaj.org/article/6fcf438297c343e7839011ffa342e579

New lucinid bivalves from shallow and deeper water of the Indian and West Pacific Oceans (Mollusca, Bivalvia, Lucinidae)

Autor: John Taylor, Emily Glover

Publikováno v: ZooKeys, Vol 326, Iss 0, Pp 69-90 (2013)

Four new species and a new genus of lucinid bivalves are described from shallow and deeper waters in the Indian and West Pacific Oceans. The new genus Scabrilucina (subfamily Lucininae) includes the little-known S. victorialis (Melvill, 1899) from th

Externí odkaz: https://doaj.org/article/21d6534fbf194ea0a793cc25e55029b1

Simulating the effects of operating room staff movement and door opening policies on microbial load

Autor: Mary Grace Stachnik, Alfredo M. Carbonell, Alexis Fiore, Taliyah Smith, Robert Allen, Emily Glover, Lawrence D. Fredendall, Kevin Taaffe, Marisa Shehan

Publikováno v: Infection Control & Hospital Epidemiology. 42:1071-1075

Objective:To identify factors that increase the microbial load in the operating room (OR) and recommend solutions to minimize the effect of these factors.Design:Observation and sampling study.Setting:Academic health center, public hospitals.Methods:W

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f55a11376f2299949a1617cbfbaaf80
https://doi.org/10.1017/ice.2020.1359

Haematopoietic stem cell gene therapy with IL‐1Ra rescues cognitive loss in mucopolysaccharidosis IIIA

Autor: Rebecca J. Holley, David Brough, Helen Parker, Hervé Boutin, Claire O'Leary, Simon Jones, Emmanuel Pinteaux, Emily Glover, Fiona L. Wilkinson, Stuart M. Ellison, Aiyin Liao, Arunabha Ghosh, Jalal Asadi, Brian W. Bigger

Publikováno v: EMBO Molecular Medicine, Vol 12, Iss 3, Pp n/a-n/a (2020)
Parker, H, Ellison, S M, Holley, R J, O'Leary, C, Liao, A, Asadi, J, Glover, E, Ghosh, A, Jones, S, Wilkinson, F L, Brough, D, Pinteaux, E, Boutin, H & Bigger, B W 2020, ' Haematopoietic stem cell gene therapy with IL-1Ra rescues cognitive loss in mucopolysaccharidosis IIIA ', EMBO Molecular Medicine, vol. 12, no. 3, e11185 . https://doi.org/10.15252/emmm.201911185
EMBO Molecular Medicine

Mucopolysaccharidosis IIIA is a neuronopathic lysosomal storage disease, characterised by heparan sulphate and other substrates accumulating in the brain. Patients develop behavioural disturbances and cognitive decline, a possible consequence of neur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::336b98f3eeaa07d928b77447092d2cd3
https://doaj.org/article/860e4ff997044c5bbd042e03d9871bf4