Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Emily Filichia"'
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0124657 (2015)
Recently the sonic hedgehog (shh) signaling pathway has been shown to play an important role in regulating repair and regenerative responses after brain injury, including ischemia. However, the precise cellular components that express and upregulate
Externí odkaz:
https://doaj.org/article/c52b0bd7984443f9abc9ce8065009cff
Autor:
Emily Filichia, Warren R. Selman, Brandon Davis, Xiaofei Zhou, Yu Luo, Tao Lv, Jonathan Pace, Barry J. Hoffer
Publikováno v:
Experimental Neurology. 283:235-245
Objective To determine the influence of the sonic hedgehog (shh) pathway and its receptor smoothened (smo), on the survival and functionality of dopaminergic (DA) neurons. Background During early development, shh induces the differentiation of DA neu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed2529dfcb0b89af8ab739a3fc894777
https://doi.org/10.1016/j.expneurol.2016.06.013
https://doi.org/10.1016/j.expneurol.2016.06.013
Autor:
Nigel H. Greig, Emily Filichia, Austin Barnett, Brandon Davis, Barry J. Hoffer, Yung Hsiao Chiang, Yu Luo, Xin Qi
Publikováno v:
Journal of Neurochemistry. 138:746-757
p53, a stress response gene, is involved in diverse cell death pathways and its activation has been implicated in the pathogenesis of Parkinson's disease (PD). However, whether the neuronal p53 protein plays a direct role in regulating dopaminergic (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8904ba0fe28636983c44fb0eaaa5adb8
https://doi.org/10.1111/jnc.13706
https://doi.org/10.1111/jnc.13706
Autor:
Barry J. Hoffer, Leslie Cooperman, Elizabeth Shick, Karran A. Phillips, Yang Sheng, Yu Luo, Emily Filichia, Zhicheng Lin, Kenzie L. Preston, Paul J. Tesar
Publikováno v:
American Journal of Psychiatry. 173:429-431
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0eec3919b4c585c24c115931286487a
https://doi.org/10.1176/appi.ajp.2015.15121545
https://doi.org/10.1176/appi.ajp.2015.15121545
Publikováno v:
Scientific Reports
Accumulating evidence suggest mitochondria-mediated pathways play an important role in dopaminergic neuronal cell death in Parkinson’s disease (PD). Drp1, a key regulator of mitochondrial fission, has been shown to be activated and translocated to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98dd4cc6b1ad770689a9153a3c11d884
https://doi.org/10.1038/srep32656
https://doi.org/10.1038/srep32656
Autor:
Yang Sheng, Leslie Cooperman, Karran A. Phillips, Barry J. Hoffer, Kenzie L. Preston, Paul J. Tesar, Elizabeth Shick, Yu Luo, Emily Filichia, Zhicheng Lin
Publikováno v:
Brain and Behavior
Introduction The dopaminergic (DA) system plays important roles in addiction. However, human DA neurons from drug-dependent subjects were not available for study until recent development in inducible pluripotent stem cells (iPSCs) technology. Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b75f24a78cf71d414bda86a2177c4eee
https://doi.org/10.1002/brb3.491
https://doi.org/10.1002/brb3.491
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0124657 (2015)
PLoS ONE
PLoS ONE
Recently the sonic hedgehog (shh) signaling pathway has been shown to play an important role in regulating repair and regenerative responses after brain injury, including ischemia. However, the precise cellular components that express and upregulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bd3dd970b18c3e9e183b5e03a503a4c
https://doi.org/10.1371/journal.pone.0124657
https://doi.org/10.1371/journal.pone.0124657