Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Emily Faivre"'
Autor:
George S, Sheppard, Le, Wang, Steven D, Fidanze, Lisa A, Hasvold, Dachun, Liu, John K, Pratt, Chang H, Park, Kenton, Longenecker, Wei, Qiu, Maricel, Torrent, Peter J, Kovar, Mai, Bui, Emily, Faivre, Xiaoli, Huang, Xiaoyu, Lin, Denise, Wilcox, Lu, Zhang, Yu, Shen, Daniel H, Albert, Terrance J, Magoc, Ganesh, Rajaraman, Warren M, Kati, Keith F, McDaniel
Publikováno v:
Journal of medicinal chemistry. 63(10)
The BET family of proteins consists of BRD2, BRD3, BRD4, and BRDt. Each protein contains two distinct bromodomains (BD1 and BD2). BET family bromodomain inhibitors under clinical development for oncology bind to each of the eight bromodomains with si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::283055280d03954bedb827a07dda077b
https://pubmed.ncbi.nlm.nih.gov/32324999
https://pubmed.ncbi.nlm.nih.gov/32324999
Autor:
Loren M. Lasko, Clarissa G. Jakob, Rohinton P. Edalji, Wei Qiu, Debra Montgomery, Enrico L. Digiammarino, T. Matt Hansen, Roberto M. Risi, Robin Frey, Vlasios Manaves, Bailin Shaw, Mikkel Algire, Paul Hessler, Lloyd T. Lam, Tamar Uziel, Emily Faivre, Debra Ferguson, Fritz G. Buchanan, Ruth L. Martin, Maricel Torrent, Gary G. Chiang, Kannan Karukurichi, J. William Langston, Brian T. Weinert, Chunaram Choudhary, Peter de Vries, Arthur F. Kluge, Michael A. Patane, John H. Van Drie, Ce Wang, David McElligott, Ed Kesicki, Ronen Marmorstein, Chaohong Sun, Philip A. Cole, Saul H. Rosenberg, Michael R. Michaelides, Albert Lai, Kenneth D. Bromberg
Publikováno v:
Nature. 550:128-132
The dynamic and reversible acetylation of proteins, catalysed by histone acetyltransferases (HATs) and histone deacetylases (HDACs), is a major epigenetic regulatory mechanism of gene transcription and is associated with multiple diseases. Histone de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fcdc4d0d1efd86b44451095a833f08b
https://doi.org/10.1038/nature24028
https://doi.org/10.1038/nature24028
Autor:
Emily Faivre
Breast cancer is a heterogeneous disease, wherein the disregulation of numerous signaling pathways can cooperate to facilitate aberrant cell growth. We endeavored to understand how Brk, a soluble PTK overexpressed in nearly two-thirds of breast tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a347953b9a7ccd562d9bcfe5c49eac3f
https://doi.org/10.21236/ada427190
https://doi.org/10.21236/ada427190
