Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Emily E. Gramling-Evans"'
Autor:
Amanda K Mika, Eric F. Johnson, Joel D. Leverson, Keith W. Woods, Michael J. Mitten, Jennifer J. Bouska, Xuesong Liu, Bradley A. Zinker, Thomas McGonigal, Richard A. Smith, Saul H. Rosenberg, Tongmei Li, Mulugeta Mamo, Anatol Oleksijew, Ron De Jong, Tilman Oltersdorf, Vincent S. Stoll, Emily E. Gramling-Evans, Alexander R. Shoemaker, Yan Luo, Vered Klinghofer, Phong T. Nguyen, Jessica A. Powlas, Sheela A. Thomas, Yan Shi, Qun Li, Ran Guan, Edward K. Han, Vincent L. Giranda
Publikováno v:
Molecular Cancer Therapeutics. 4:977-986
The Akt kinases are central nodes in signal transduction pathways that are important for cellular transformation and tumor progression. We report the development of a series of potent and selective indazole-pyridine based Akt inhibitors. These compou
Autor:
Akhter Molla, Leo W. Barrett, Stephen F. Betz, Kevin Steffy, Kent D. Stewart, Jeffrey R. Huth, Paul L. Richardson, Jean M. Severin, Steve Muchmore, John E. Harlan, Dale J. Kempf, Kevin S. Harris, Edmund D. Matayoshi, Renaldo R. Mendoza, Vincent S. Stoll, Karl A. Walter, Kerry M. Swift, Emily E. Gramling-Evans
Publikováno v:
Journal of computer-aided molecular design. 21(1-3)
Two new proteins of approximately 70 amino acids in length, corresponding to an unnaturally-linked N- and C-helix of the ectodomain of the gp41 protein from the human immunodeficiency virus (HIV) type 1, were designed and characterized. A designed tr
Autor:
Stewart KD; Department of Structural Biology, Abbott Laboratories, Building AP10, 100 Abbott Park Road, Abbott Park, IL 60064, USA. kent.stewart@abbott.com, Steffy K, Harris K, Harlan JE, Stoll VS, Huth JR, Walter KA, Gramling-Evans E, Mendoza RR, Severin JM, Richardson PL, Barrett LW, Matayoshi ED, Swift KM, Betz SF, Muchmore SW, Kempf DJ, Molla A
Publikováno v:
Journal of computer-aided molecular design [J Comput Aided Mol Des] 2007 Jan-Mar; Vol. 21 (1-3), pp. 121-30. Date of Electronic Publication: 2007 Feb 09.