Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Emily E. Bosco"'
Autor:
Peter Zanvit, Dewald van Dyk, Christine Fazenbaker, Kelly McGlinchey, Weichuan Luo, Jessica M. Pezold, John Meekin, Chien-ying Chang, Rosa A. Carrasco, Shannon Breen, Crystal Sao-Fong Cheung, Ariel Endlich-Frazier, Benjamin Clark, Nina J. Chu, Alessio Vantellini, Philip L. Martin, Clare E. Hoover, Kenesha Riley, Steve M. Sweet, David Chain, Yeoun Jin Kim, Eric Tu, Nathalie Harder, Sandrina Phipps, Melissa Damschroder, Ryan N. Gilbreth, Mark Cobbold, Gordon Moody, Emily E. Bosco
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 22 (2023)
Prostate cancer is generally considered an immunologically “cold” tumor type that is insensitive to immunotherapy. Targeting surface antigens on tumors through cellular therapy can induce a potent antitumor immune response to “heat up” the tu
Externí odkaz:
https://doaj.org/article/e772d4b790a848fcb94aa4259efad645
Autor:
Dewald van Dyk, Peter Zanvit, Christine Fazenbaker, Kelly McGlinchey, Weichuan Luo, Jessica Pezold, John Meekin, Chien-ying Chang, Benjamin Clark, Philip L. Martin, Clare Hoover, Eric Tu, Ryan Gilbreth, Mark Cobbold, Gordon Moody, Emily E. Bosco
Publikováno v:
Cancer Research. 83:LB085-LB085
Prostate cancer is traditionally considered an immunologically “cold” tumor type rendering patients insensitive to immunotherapy. Targeting surface antigens on tumors through cellular therapy can induce a potent anti tumor immune response to “h
Autor:
William A. Zagorski, K. Scott Luce, Jeanette Gowen Cook, Erik S. Knudsen, Emily E. Bosco, Michael F. Reed, Wesley A. Braden, Jon M. Lenihan, Zhengdao Lan
Publikováno v:
Mol Cell Biol
The retinoblastoma (RB) and p16ink4a tumor suppressors are believed to function in a linear pathway that is functionally inactivated in a large fraction of human cancers. Recent studies have shown that RB plays a critical role in regulating S phase a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1fdd83d5f94ea6895cc19816b427b87
https://europepmc.org/articles/PMC7431046/
https://europepmc.org/articles/PMC7431046/
Autor:
John Meekin, Haihong Zhong, Maureen Kennedy, Rosa A. Carrasco, Ronald Herbst, Sandrina Phipps, Binyam Bezabeh, R. James Christie, Karma Dacosta, David A. Tice, Emily E. Bosco, Jiping Zha, Rakesh Dixit, Partha S. Chowdhury, Joanne Ayriss, Qun Du, Zhan Xiao, Darrin Sabol, MaryJane Hinrichs, Cui Chen, Shannon Breen, Lee Brown, Molly Reed
Publikováno v:
Oncotarget
Despite recent advances in treatment, breast cancer remains the second-most common cause of cancer death among American women. A greater understanding of the molecular characteristics of breast tumors could ultimately lead to improved tumor-targeted
Autor:
Ronald Herbst, David A. Tice, Robert E. Hollingsworth, Sarah Conley, Zhan Xiao, Emily E. Bosco
Publikováno v:
Oncogene
Mucin-like 1 (MUCL1) was first identified as a breast-specific gene over a decade ago. Based on its highly restricted mRNA expression in breast tissue and continued expression during breast tumorigenesis and progression, MUCL1 is an attractive tumor-
Autor:
Lee Brown, Sandrina Phipps, Molly Reed, Haihong Zhong, Darrin Sabol, Rakesh Dixit, MaryJane Hinrichs, Qun Du, Binyam Bezabeh, Ronald James Christie, Cui Chen, Shannon Breen, Jiping Zha, Zhan Xiao, Karma Dacosta, Emily E. Bosco, Ronald Herbst, Rosa A. Carrasco, David A. Tice
Publikováno v:
Cancer Research. 78:759-759
Despite recent advances in treatment, breast cancer remains the second-most common cause of cancer death among American women. A greater understanding of the molecular characteristics of individual tumors could ultimately lead to improved treatment o
Publikováno v:
Oncogene
The neurofibromatosis type 2 (NF2) tumor suppressor gene encodes merlin, a membrane/cytoskeleton protein necessary for maintenance of contact inhibition of growth in cells. Biallelic inactivation of NF2 is known to cause multiple cancers in both huma
Publikováno v:
Cellular and Molecular Life Sciences. 66:370-374
Rac1, a member of the Rho family of GTPases, is an intracellular transducer known to regulate multiple signaling pathways that control cytoskeleton organization, transcription, and cell proliferation. Deregulated expression or activation patterns of
Autor:
Gloria Bonuccelli, Erik S. Knudsen, Federica Sotgia, Huan Xu, Emily E. Bosco, Christiane Danilo, Chenguang Wang, Judy N. Quong, Michael P. Lisanti, Bruce J. Aronow, Kathleen G. Allen, Alimatou Minkeu, Isabelle Mercier, Richard G. Pestell, Mathew C. Casimiro, Anne L. Rosenberg, Jean-Francois Jasmin, Agnieszka K. Witkiewicz
Publikováno v:
Cancer Biology & Therapy. 7:1212-1225
It is becoming increasingly apparent that the tumor microenvironment plays a critical role in human breast cancer onset and progression. Therefore, we isolated cancer-associated fibroblasts (CAFs) from human breast cancer lesions and studied their pr
Autor:
K. Scott Luce, Jon M. Lenihan, Emily E. Bosco, Erik S. Knudsen, William A. Zagorski, Zhengdao Lan, Wesley A. Braden, Jeanette Gowen Cook, Michael F. Reed
Publikováno v:
Molecular and Cellular Biology. 26:7667-7681
The retinoblastoma (RB) and p16ink4a tumor suppressors are believed to function in a linear pathway that is functionally inactivated in a large fraction of human cancers. Recent studies have shown that RB plays a critical role in regulating S phase a