Zobrazeno 1 - 10
of 166
pro vyhledávání: '"Emily E, Brown"'
Autor:
Michelle Lee Lynskey, Emily E. Brown, Ragini Bhargava, Anne R. Wondisford, Jean-Baptiste Ouriou, Oliver Freund, Ray W. Bowman, II, Baylee A. Smith, Santana M. Lardo, Sandra Schamus-Hayes, Sarah J. Hainer, Roderick J. O’Sullivan
Publikováno v:
Cell Reports, Vol 43, Iss 11, Pp 114964- (2024)
Summary: Inactivating mutations in chromatin modifiers, like the α-thalassemia/mental retardation, X-linked (ATRX)-death domain-associated protein (DAXX) chromatin remodeling/histone H3.3 deposition complex, drive the cancer-specific alternative len
Externí odkaz:
https://doaj.org/article/ace7bcd0d4f64686af98119f8cb927c3
Autor:
Emily E. Brown, Kathleen Byrne, Erin D. Michos, Thorsten M. Leucker, Francoise Marvel, Steven R. Jones, Seth S. Martin, Marios Arvanitis
Publikováno v:
American Journal of Preventive Cardiology, Vol 18, Iss , Pp 100683- (2024)
Objective: Assess the yield of genetic testing for pathogenic variants in ABCG5, ABCG8, LIPA, and APOE in individuals with personal and family histories suggestive of familial hypercholesterolemia. Methods: Retrospective review of patients seen in th
Externí odkaz:
https://doaj.org/article/27fbfa8eb7b34aabab91d473d8a8d56a
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 29, Iss , Pp 319-328 (2023)
Nicotinamide nucleotide adenylyltransferase 1 (NMNAT1) is a ubiquitously expressed enzyme involved in nuclear NAD+ production throughout the body. However, mutations in the NMNAT1 gene lead to retina-specific disease with few reports of systemic effe
Externí odkaz:
https://doaj.org/article/faddedac51f94ab78768198b03842ef8
Publikováno v:
American Heart Journal Plus, Vol 21, Iss , Pp 100146- (2022)
Externí odkaz:
https://doaj.org/article/e8db36ed8bc9488ebc1d3e107364a35c
Autor:
Scott H. Greenwald, Emily E. Brown, Michael J. Scandura, Erin Hennessey, Raymond Farmer, Basil S. Pawlyk, Ru Xiao, Luk H. Vandenberghe, Eric A. Pierce
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 18, Iss , Pp 582-594 (2020)
No treatment is available for nicotinamide mononucleotide adenylyltransferase 1 (NMNAT1)-associated retinal degeneration, an inherited disease that leads to severe vision loss early in life. Although the causative gene, NMNAT1, plays an essential rol
Externí odkaz:
https://doaj.org/article/5d02e3397cf744a298ba15f2fe1d0c82
Autor:
Han Zou, Bradley Poore, Emily E. Brown, Jieqi Qian, Bin Xie, Evridiki Asimakidou, Vladislav Razskazovskiy, Deanna Ayrapetian, Vaibhav Sharma, Shunjin Xia, Fei Liu, Apeng Chen, Yongchang Guan, Zhengwei Li, Siyi Wanggou, Olivier Saulnier, Michelle Ly, Wendy Fellows-Mayle, Guifa Xi, Tadanori Tomita, Adam C. Resnick, Stephen C. Mack, Eric H. Raabe, Charles G. Eberhart, Dandan Sun, Beth E. Stronach, Sameer Agnihotri, Gary Kohanbash, Songjian Lu, Karl Herrup, Jeremy N. Rich, George K. Gittes, Alberto Broniscer, Zhongliang Hu, Xuejun Li, Ian F. Pollack, Robert M. Friedlander, Sarah J. Hainer, Michael D. Taylor, Baoli Hu
Publikováno v:
Nature Cell Biology. 25:493-507
How abnormal neurodevelopment relates to the tumour aggressiveness of medulloblastoma (MB), the most common type of embryonal tumour, remains elusive. Here we uncover a neurodevelopmental epigenomic programme that is hijacked to induce MB metastatic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0f51592b0e8eb2d91bf16cf1f0905d6
https://doi.org/10.1038/s41556-023-01093-0
https://doi.org/10.1038/s41556-023-01093-0
Autor:
Lei Xu, Emily E. Brown, Clayton P. Santiago, Casey J. Keuthan, Ekaterina Lobanova, John D. Ash
Publikováno v:
Redox Biology, Vol 37, Iss , Pp 101700- (2020)
Peroxisome proliferator-activated receptors (PPARs) are a family of three nuclear hormone receptors (PPARα, PPARδ, and PPARγ) that are known to regulate expression of lipid metabolism and oxidative stress genes. Given their role in reducing oxidat
Externí odkaz:
https://doaj.org/article/1241fff1d60447eeb5be46e2d845e683
Publikováno v:
ACS Central Science. 8:1548-1556
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ac1cdf49c3402cd2531c971027b521f
https://doi.org/10.1021/acscentsci.2c01003
https://doi.org/10.1021/acscentsci.2c01003
Publikováno v:
Redox Biology, Vol 24, Iss , Pp - (2019)
Age-related macular degeneration (AMD) is the leading cause of vision loss in the western world. Recent evidence suggests that RPE and photoreceptors have an interconnected metabolism and that mitochondrial damage in RPE is a trigger for degeneration
Externí odkaz:
https://doaj.org/article/d3a20b25ebc14cf2835db514ad5d3d29
Publikováno v:
AIP Advances, Vol 8, Iss 5, Pp 056108-056108-5 (2018)
Varied thickness body centered cubic (BCC) ultrathin Fe films (10-50Å) have been sputter deposited onto Si (111) substrates. BCC Fe with the novel (222) texture was obtained by H- terminating the Si (111) starting substrate then immediately depositi
Externí odkaz:
https://doaj.org/article/52c3114b9b0f4cb7b0e96c618360381a