Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Emily Dookun"'
Autor:
Rhys Jones, Amaran Krishnan, Gemma L. Zeybel, Emily Dookun, Jeffrey P. Pearson, A. John Simpson, S. Michael Griffin, Chris Ward, Ian A. Forrest
Publikováno v:
ERJ Open Research, Vol 4, Iss 4 (2018)
Externí odkaz:
https://doaj.org/article/7f11d01b34fc40b08a427a78f9dbd841
Autor:
Rachael Redgrave, Emily Dookun, Laura Booth, Omowumi Folaranm, Simon Tual-Chalot, Jason Gill, Andrew Owens, Ioakim Spyridopoulos, Joao Passos, Gavin Richardson
Myocardial infarction is a leading cause of morbidity and mortality. While reperfusion is now standard therapy, pathological remodeling leading to heart failure remains a clinical problem. Cellular senescence has been shown to contribute to disease p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58fca09f64e6cb356227a20cecdf7e68
https://doi.org/10.21203/rs.3.rs-2776501/v1
https://doi.org/10.21203/rs.3.rs-2776501/v1
Publikováno v:
Cardiovascular Drugs and Therapy
Ageing is the biggest risk factor for impaired cardiovascular health, with cardiovascular disease being the leading cause of death in 40% of individuals over 65 years old. Ageing is associated with both an increased prevalence of cardiovascular disea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::061ca1eeb9a9cb10d9d3740f0af6ac9b
https://doi.org/10.1007/s10557-020-07075-w
https://doi.org/10.1007/s10557-020-07075-w
Publikováno v:
Mechanisms of Ageing and Development
Highlights • Studies have demonstrated that senescence contributes to the pathophysiology of several age-related cardiovascular diseases. • Senolytics eliminate senescent cells in cardiovascular tissues and prevent or reverse disease progression.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61fff4ff108d2a3beefb6ee1b16fa8a0
https://pubmed.ncbi.nlm.nih.gov/34237321
https://pubmed.ncbi.nlm.nih.gov/34237321
Publikováno v:
EP Europace. 22
Funding Acknowledgements Investigator Sponsored Research grant from Boston Scientific Introduction Irrigated catheters are the standard tool for radiofrequency (RF) ablation in the left atrium and ventricles. However, pathological studies of irrigate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fcddbeccc80d817f0078d875630ab0a
https://doi.org/10.1093/europace/euaa162.234
https://doi.org/10.1093/europace/euaa162.234
Autor:
David J. Grieve, James Chapman, Gavin D. Richardson, Emily Dookun, Anna Walaszczyk, Eleanor K Gill, Helen M. Arthur, Rachael Redgrave, Eduard Jirkovsky, Oliver E Yausep, Averina Suwana, Pawel Palmowski, Yohan Santin, Michael J. Taggart, Leticia Donastorg Sosa, Simon Tual-Chalot, João F. Passos, Jeanne Mialet-Perez, Ioakim Spyridopoulos, W. Andrew Owens
A key component of cardiac ischemia-reperfusion injury (IRI) is the increased generation of reactive oxygen species, leading to enhanced inflammation and tissue dysfunction in patients following intervention for myocardial infarction. In this study w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e85576f8a9fb70cbfafcc3b50b033bb
Autor:
Gemma Louise Zeybel, Ian Forrest, Emily Dookun, A Krishnan, Jeffrey P. Pearson, S. Michael Griffin, Rhys Jones, A. John Simpson, Chris Ward
Publikováno v:
ERJ Open Research, Vol 4, Iss 4 (2018)
ERJ Open Research
ERJ Open Research
Despite recent therapeutic advances, the prognosis for patients with idiopathic pulmonary fibrosis (IPF) remains poor. The link with gastro-oesophageal reflux disease (GORD) has been identified as a research priority, as GORD appears to be common in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6467eb02a5dc06c7b68fbc4827df21d3
https://doi.org/10.1183/23120541.00051-2018
https://doi.org/10.1183/23120541.00051-2018
Publikováno v:
The EMBO Journal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=r3c4b2081b22::36fdc28b289fed700b917977cdae0cc3
Publikováno v:
Aging Cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=r3c4b2081b22::cecd9f037df26ca9743799a1df22d09b
Autor:
Douin-Echinard, Marissa J. Schafer, João F. Passos, Diana Jurk, Stella Victorelli, Rolando Berlinguer-Palmini, Helen M. Arthur, Neil Robertson, Damien Maggiorani, Emily Dookun, Laura C. Greaves, Simon Tual-Chalot, Carolyn M Roos, Clara Correia-Melo, Jordan D. Miller, Mikolaj Ogrodnik, Rhys Anderson, Anna Walaszczyk, Anthony B. Lagnado, Carole J. Proctor, James L. Kirkland, Edward Fielder, Jelena Mann, James Chapman, Gavin D. Richardson, Tamara Tchkonia, Nathan K. LeBrasseur, A Owens, Hanna Salmonowicz, Angelo Parini, Peter D. Adams, Kathy L Kolsky, Jodie Birch, Jeanne Mialet-Perez
Ageing is the biggest risk factor for cardiovascular health and is associated with increased incidence of cardiovascular disease. Cellular senescence, a process driven in part by telomere shortening, has been implicated in age-related tissue dysfunct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8358e6711b67f684e1842e1f6fcc71a