Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Emily D. Varnell"'
Publikováno v:
Current Eye Research. 29:119-125
To investigate the effect of acetylsalicylic acid on ocular shedding of herpes simplex virus type 1 (HSV-1).Mice that were latent for the McKrae strain of HSV-1 were treated with acetylsalicylic acid, a nonspecific inhibitor of cyclooxygenases, eithe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea6317b04e53b048fe603c1b2a7feb85
https://doi.org/10.1080/02713680490504588
https://doi.org/10.1080/02713680490504588
Publikováno v:
American Journal of Ophthalmology. 136:593-602
Purpose To investigate whether conjunctival inflammation represents a primary event in the pathogenesis of keratoconjunctivitis sicca or whether it is a secondary inflammatory reaction caused by enhanced mechanical irritation as a result of surface d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7f9536743da2fe56fa44f6dc3761cbc
https://doi.org/10.1016/s0002-9394(03)00326-x
https://doi.org/10.1016/s0002-9394(03)00326-x
Autor:
Emily D. Varnell, Bryan M. Gebhardt, Sang W. Kang, Ho Y. Lim, Shiro Higaki, Herbert E. Kaufman, Su K. Seo, James M. Hill, Byoung S. Kwon
Publikováno v:
European Journal of Immunology. 31:3318-3328
Keratocytes express MHC class I molecules constitutively, and keratocytes stimulated with IFN-gamma express MHC class II molecules. Unstimulated keratocytes constitutively express B7-1 and ICAM-1, as well as low levels of CD40 and 4-1BBL. These findi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab99ba1fb6b59846f5f91583af96588b
https://doi.org/10.1002/1521-4141(200111)31:11<3318::aid-immu3318>3.0.co
https://doi.org/10.1002/1521-4141(200111)31:11<3318::aid-immu3318>3.0.co
Publikováno v:
Transplantation. 67:594-599
Background. In this study, we determined the binding characteristics of F(ab') 2 alloantibody fragments to corneal antigens and assessed the capacity of these antibody fragments to protect corneal allografts from immune attack. Methods. Goat anti-rab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9869f8112b7232c0b180dc590a68bd27
https://doi.org/10.1097/00007890-199902270-00018
https://doi.org/10.1097/00007890-199902270-00018
Autor:
Hongyan Xu, Emily D. Varnell, Hilary W. Thompson, George E. Wright, Herbert E. Kaufman, Bryan M. Gebhardt
Publikováno v:
Antiviral Research. 33:65-72
9-(4-Hydroxybutyl)- N 2 -phenylguanine (HBPG) is a new viral thymidine kinase inhibitor that we tested for the ability to prevent recurrences of herpetic keratitis. Eighteen squirrel monkeys ( Saimiri scuireus ) were infected in both corneas with the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::099c7c03fd58b095003e72aeec80d5c7
https://doi.org/10.1016/s0166-3542(96)00997-7
https://doi.org/10.1016/s0166-3542(96)00997-7
Publikováno v:
Current Eye Research. 15:680-684
Hyperthermia has been shown to induce HSV-1 ocular shedding in mice. Systemic administration of propranolol significantly reduced the recovery of infectious virus in the tears, cornea, and trigeminal ganglia of mice subjected to hyperthermia. The pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c274358ce22605412b84e7f20445b2a
https://doi.org/10.3109/02713689609008909
https://doi.org/10.3109/02713689609008909
Autor:
Hilary W. Thompson, Jean T. JACOB-LaBARRE, Emily D. Varnell, Erica Lehman, Herbert E. Kaufman, Thomas L. Steinemann, Bryan M. Gebhardt
Publikováno v:
Journal of Ocular Pharmacology and Therapeutics. 10:17-27
For patients with conditions requiring chronic rather than acute therapy, the advantages of collagen shields in providing high and sustained levels of drugs and/or lubricants to the cornea are outweighed by the difficulty of insertion of the shield a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::623a3b525a76fdfcb11432d9df5c8626
https://doi.org/10.1089/jop.1994.10.17
https://doi.org/10.1089/jop.1994.10.17
Autor:
Lena J Al-Dujaili, Harris E. McFerrin, Emily D. Varnell, Patrick P Clerkin, James M. Hill, Partha S. Bhattacharjee, Herbert E. Kaufman, Christian Clement
Publikováno v:
Future microbiology. 6(8)
Most humans are infected with herpes simplex virus (HSV) type 1 in early childhood and remain latently infected throughout life. While most individuals have mild or no symptoms, some will develop destructive HSV keratitis. Ocular infection with HSV-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2a90ef9f4e18588eaa0a2bd966d865f
https://pubmed.ncbi.nlm.nih.gov/21861620
https://pubmed.ncbi.nlm.nih.gov/21861620
Autor:
Jeffery A. Hobden, Manish Kumar, Emily D. Varnell, Partha S. Bhattacharjee, Herbert E. Kaufman, James M. Hill, Christian Clement
Herpes simplex virus type 1 (HSV-1) is a common cause of acute and recurrent ophthalmic disease worldwide1,2 and is the leading cause of infectious blindness in the United States.1,3 HSV-1 infections of the cornea typically result in sight-threatenin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ee4ab5b4c65e52d743a4c24b67699f6
https://europepmc.org/articles/PMC3053108/
https://europepmc.org/articles/PMC3053108/
Autor:
Thomas L. Steinemann, Herbert E. Kaufman, Roger W. Beuerman, Kenneth E. Aldridge, Emily D. Varnell, Hilary W. Thompson
Publikováno v:
American Journal of Ophthalmology. 113:555-560
Antibiotics in a corneal preservation solution probably have little effect during storage at 4 C, but are effective as the tissue is warmed. The tissue acts as a sponge, soaking up the antibiotic from the solution and releasing it into the eye, where
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c506ad67a7066be48074b9f17de9b65a
https://doi.org/10.1016/s0002-9394(14)74729-4
https://doi.org/10.1016/s0002-9394(14)74729-4