Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Emily Crowley"'
Autor:
Alberto Bardelli, Federica Di Nicolantonio, Sandra Misale, Emily Crowley, Beth O. Van Emburgh, Sebastijan Hobor
Purpose: Targeted inhibition of EGFR with the mAbs cetuximab or panitumumab is a valuable treatment for RAS wild-type colorectal cancers. The efficacy of EGFR blockade is limited by the emergence of acquired resistance often attributed to secondary K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d85d558fc3afb9d2301729feca15f59b
https://doi.org/10.1158/1078-0432.c.6523887
https://doi.org/10.1158/1078-0432.c.6523887
Autor:
Alberto Bardelli, Federica Di Nicolantonio, Sandra Misale, Emily Crowley, Beth O. Van Emburgh, Sebastijan Hobor
PDF file - 38K, Alternative comparative presentation of results presented in Figure 3 C-F.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6545b8f3aa8a337a8cc5ec782b6ca9f9
https://doi.org/10.1158/1078-0432.22458255.v1
https://doi.org/10.1158/1078-0432.22458255.v1
Autor:
Alberto Bardelli, Federica Di Nicolantonio, Sandra Misale, Emily Crowley, Beth O. Van Emburgh, Sebastijan Hobor
PDF file - 133K, Measurements of additional receptor ligands from conditioned media.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ce35d1b1e4cbfdd96554e159da1fda4
https://doi.org/10.1158/1078-0432.22458258
https://doi.org/10.1158/1078-0432.22458258
Autor:
Alberto Bardelli, Federica Di Nicolantonio, Sandra Misale, Emily Crowley, Beth O. Van Emburgh, Sebastijan Hobor
PDF file - 118K, LIM1215 knocked-in with a KRAS G12R mutation are also capable of paracrine protection of sensitive wild type (wt) cells and secrete higher levels of TGFalpha.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7401f9ac92d87b00054aee4caa915ce5
https://doi.org/10.1158/1078-0432.22458252
https://doi.org/10.1158/1078-0432.22458252
Autor:
Alberto Bardelli, Federica Di Nicolantonio, Sandra Misale, Emily Crowley, Beth O. Van Emburgh, Sebastijan Hobor
PDF file - 95K, Schematic representation of conditioned medium assay (CMA).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64f9af0d94a003b9a077893afda4ed76
https://doi.org/10.1158/1078-0432.22458261.v1
https://doi.org/10.1158/1078-0432.22458261.v1
Publikováno v:
The FEBS Journal. 287:4917-4932
Autophagy plays a role in several human diseases, but each of the current methods to measure autophagy has significant drawbacks. ATG5 and ATG16L1 are regulators necessary for autophagy; therefore, drugs that inhibit the interaction of these proteins
Natural and Synthetic Isothiocyanates Possess Anticancer Potential Against Liver and Prostate Cancer
Publikováno v:
Anticancer research. 39(7)
Background/Aim: Isothiocyanates (ITCs) are phytochemicals with potential cancer-preventative properties derived from the breakdown of glucosinolates that exist in cruciferous vegetables. Studies, to date, have demonstrated that various ITCs possess t
Autor:
Beth O. Van Emburgh, Sebastijan Hobor, Federica Di Nicolantonio, Alberto Bardelli, Sandra Misale, Emily Crowley
Publikováno v:
Clinical Cancer Research. 20:6429-6438
Purpose: Targeted inhibition of EGFR with the mAbs cetuximab or panitumumab is a valuable treatment for RAS wild-type colorectal cancers. The efficacy of EGFR blockade is limited by the emergence of acquired resistance often attributed to secondary K