Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Emily C. Sutton"'
Autor:
Hannah C. Pigg, Matthew V. Yglesias, Emily C. Sutton, Christine E. McDevitt, Michael Shaw, Victoria J. DeRose
Publikováno v:
ACS chemical biology. 17(8)
The properties of small molecule Pt(II) compounds that drive specific cellular responses are of interest due to their broad clinical use as chemotherapeutics as well as to provide a better mechanistic understanding of bioinorganic processes. The chem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5113f591bd5b694cd97974985c8782c0
https://pubmed.ncbi.nlm.nih.gov/35917257
https://pubmed.ncbi.nlm.nih.gov/35917257
Autor:
Min Chieh Yang, Emily C. Sutton, Victoria J. DeRose, Jack Y Prochnau, Christine E. McDevitt, Matthew V. Yglesias, Christopher H. Hendon, Austin M. Mroz, Rachael M. Cunningham
Publikováno v:
J Am Chem Soc
Platinum(II) compounds are a critical class of chemotherapeutic agents. Recent studies have highlighted the ability of a subset of Pt(II) compounds, including oxaliplatin but not cisplatin, to induce cytotoxicity via nucleolar stress rather than a ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1999d388410a9b3a6dad4c58a08f5e26
https://doi.org/10.1021/jacs.9b10319
https://doi.org/10.1021/jacs.9b10319
Autor:
Emily C. Sutton, Christopher H. Hendon, Matthew V. Yglesias, Min Chieh Yang, Victoria J. DeRose, Christine E. McDevitt, Austin M. Mroz
Publikováno v:
J Biol Inorg Chem
Platinum anticancer therapeutics are widely used in a variety of chemotherapy regimens. Recent work has revealed that the cytotoxicity of oxaliplatin and phenanthriplatin is through induction of ribosome biogenesis stress pathways, differentiating th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76b3404d44d215dfd45058e06d129802
https://pubmed.ncbi.nlm.nih.gov/31494760
https://pubmed.ncbi.nlm.nih.gov/31494760
Publikováno v:
The FASEB Journal. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::795151c117ab764280880b01ebbf0961
https://doi.org/10.1096/fasebj.2019.33.1_supplement.471.17
https://doi.org/10.1096/fasebj.2019.33.1_supplement.471.17
Autor:
Emily C. Sutton, Victoria J. DeRose
Publikováno v:
The Journal of Biological Chemistry
Recent reports provide evidence that the platinum chemotherapeutic oxaliplatin causes cell death via ribosome biogenesis stress, while cisplatin causes cell death via the DNA damage response (DDR). Underlying differences in mechanisms that might init
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af3e00feaf0ad09feaf480419bab7edc
https://doi.org/10.1016/j.jbc.2021.100633
https://doi.org/10.1016/j.jbc.2021.100633