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pro vyhledávání: '"Emily C. Glassberg"'
Publikováno v:
The American Journal of Human Genetics. 105:189-197
Women are under-represented in science, technology, engineering, and mathematics (STEM). Despite the recent emphasis on diversity in STEM, our understanding of what drives differences between women and men scientists remains limited. This, in turn, l
Publikováno v:
Genetics
Variation in human complex traits is connected to variation in gene expression, and selection on complex traits can be reflected in selection on gene expression. Here, Glassberg and Gao et al. analyze polymorphic....
Gene expression variation is
Gene expression variation is
Autor:
Ilana M. Arbisser, Emily C. Glassberg, Lawrence H. Uricchio, Noah A. Rosenberg, Alissa L. Severson
Publikováno v:
Theor Popul Biol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::556831c6b413024729ebe92e1851935f
https://europepmc.org/articles/PMC6746670/
https://europepmc.org/articles/PMC6746670/
Gene expression variation is a major contributor to phenotypic variation in human complex traits. Selection on complex traits may therefore be reflected in constraint on gene expression levels. Here, we explore the effects of stabilizing selection on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96c8c31e0628cdcdc40bcf971754a1d3
Publikováno v:
Journal of The Royal Society Interface. 15:20170921
Within-host adaptation of pathogens such as human immunodeficiency virus (HIV) often occurs at more than two loci. Multiple beneficial mutations may arise simultaneously on different genetic backgrounds and interfere, affecting each other's fixation
Publikováno v:
BioRxiv
The adaptation of asexually reproducing organisms is determined by how they accrue beneficial mutations. In large populations, multiple beneficial mutations may arise simultaneously on different genetic backgrounds and interfere with the fixation tra