Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Emily C. Brantley"'
Autor:
Etty N. Benveniste, Kevin Roarty, Keith Harrison, Cheryl Ann Palmer, Youn-Hee Choi, G. Yancey Gillespie, L. Burton Nabors, Emily C. Brantley
Purpose: STATs activate transcription in response to numerous cytokines, controlling proliferation, gene expression, and apoptosis. Aberrant activation of STAT proteins, particularly STAT-3, is implicated in the pathogenesis of many cancers, includin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::224ff55fdcbb8d843ad0bb5dbd46ea49
https://doi.org/10.1158/1078-0432.c.6516970.v1
https://doi.org/10.1158/1078-0432.c.6516970.v1
Publikováno v:
Cancer Research. 71:6561-6566
Progression of melanoma is dependent on cross-talk between tumor cells and the adjacent microenvironment. The thrombin receptor, protease-activated receptor-1 (PAR-1), plays a key role in exerting this function during melanoma progression. PAR-1 and
Autor:
Emily C. Brantley, L. Burton Nabors, G. Yancey Gillespie, Kevin Roarty, Cheryl A. Palmer, Etty N. Benveniste, Youn Hee Choi, Keith Harrison
Publikováno v:
Clinical Cancer Research. 14:4694-4704
Purpose: STATs activate transcription in response to numerous cytokines, controlling proliferation, gene expression, and apoptosis. Aberrant activation of STAT proteins, particularly STAT-3, is implicated in the pathogenesis of many cancers, includin
Autor:
Emily C. Brantley, Etty N. Benveniste
Publikováno v:
Molecular Cancer Research. 6:675-684
Glioblastoma is the most common and severe primary brain tumor in adults. Its aggressive and infiltrative nature renders the current therapeutics of surgical resection, radiation, and chemotherapy relatively ineffective. Accordingly, recent research
Autor:
Isaiah J. Fidler, Qiuyu Wu, Marva Maya, Seok Joong Yun, Jang Seong Kim, Urs Regenass, Emily C. Brantley, François Lehembre, Seung Wook Kim, Fahao Zhang, Sun Jin Kim, Junqin He
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 13, Iss 2, Pp 167-179 (2011)
Potential treatments for ovarian cancers that have become resistant to standard chemotherapies include modulators of tumor cell survival, such as endothelin receptor (ETR) antagonist. We investigated the therapeutic efficacy of the dual ETR antagonis
Autor:
Emily C. Brantley, Lixia Guo, Joseph H. McCarty, Qingtang Lin, Chenyu Zhang, Robert R. Langley, Dominic Fan, Isaiah J. Fidler
Publikováno v:
International journal of oncology. 35(4)
Astrocytes play a critical role in maintaining cerebral homeostasis and their dysregulation is thought to contribute to the pathogenesis of several diseases, including brain cancer and metastasis. Similar to the human disease, we found that lung and
Autor:
Emily C. Brantley, Fahao Zhang, François Lehembre, Isaiah J. Fidler, Seung Wook Kim, Maya K. Marva, Qiuyu Wu, Seok Joong Yun, Jang Seong Kim, Urs Regenass, Sun Jin Kim, Junqin He
Publikováno v:
Cancer Research. 71:601-601
Introduction: In 2009, ovarian cancer was the leading cause of death from gynecologic cancer in the United States. Efforts to develop tools for early detection and therapeutic regimens to overcome drug resistance of the ovarian cancer have not made a
Autor:
François Lehembre, Panja Strickner, Sun Jin Kim, Junqin He, Seok Joong Yun, Jang Seong Kim, Urs Regenass, Emily C. Brantley, Seung Wook Kim, Isaiah J. Fidler, Dominic Fan
Publikováno v:
Translational Oncology. (1):39-47
Endothelin receptors (ETRs) are often overexpressed in ovarian tumors, which can be resistant to conventional therapies. Thus, we investigated whether blockage of the ETR pathways using the dual ETR antagonist macitentan combined with taxol or cispla
Autor:
Kenji Yokoi, Lixia Guo, Chenyu Zhang, Sun Jin Kim, Emily C. Brantley, Qingtang Lin, Robert R. Langley, Ewa Kruzel, Isaiah J. Fidler, Marva Maya, Seung Wook Kim, Dominic Fan
Publikováno v:
Translational Oncology. (6):380-388
Experimental metastases in the brain of mice are infiltrated by microglia, and parabiosis experiments of green fluorescent protein (GFP+) and GFP- mice revealed that these microglia are derived from circulating monocytes (GFP+, F4/80+, and CD68+). Th