High-throughput interaction screens illuminate the role of c-di-AMP in cyanobacterial nighttime survival.

Autor: Benjamin E Rubin, TuAnh Ngoc Huynh, David G Welkie, Spencer Diamond, Ryan Simkovsky, Emily C Pierce, Arnaud Taton, Laura C Lowe, Jenny J Lee, Scott A Rifkin, Joshua J Woodward, Susan S Golden

Publikováno v: PLoS Genetics, Vol 14, Iss 4, p e1007301 (2018)

The broadly conserved signaling nucleotide cyclic di-adenosine monophosphate (c-di-AMP) is essential for viability in most bacteria where it has been studied. However, characterization of the cellular functions and metabolism of c-di-AMP has largely

Externí odkaz: https://doaj.org/article/a5df8d1f01f74288bd19d346606f60f9

Longitudinal, Multi-Platform Metagenomics Yields a High-Quality Genomic Catalog and Guides an In Vitro Model for Cheese Communities

Autor: Christina C. Saak, Emily C. Pierce, Cong B. Dinh, Daniel Portik, Richard Hall, Meredith Ashby, Rachel J. Dutton

Publikováno v: mSystems, Vol 8, Iss 1 (2023)

ABSTRACT Microbiomes are intricately intertwined with human health, geochemical cycles, and food production. While many microbiomes of interest are highly complex and experimentally intractable, cheese rind microbiomes have proven to be powerful mode

Externí odkaz: https://doaj.org/article/b73e6d105ed543bebbf2e4a7b952bf13

Putting microbial interactions back into community contexts

Autor: Emily C Pierce, Rachel J. Dutton

Publikováno v: Current Opinion in Microbiology. 65:56-63

Microbial interactions are key aspects of the biology of microbiomes. Recently, there has been a shift in the field towards studying interactions in more representative contexts, whether using multispecies model microbial communities or by looking at

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33ba6347bd3435471aa999e85d6b46c0
https://doi.org/10.1016/j.mib.2021.10.008

A community resource for paired genomic and metabolomic data mining

Autor: Lars Ridder, Tim S. Bugni, Jamshid Amiri Moghaddam, Florian Huber, Elke Dittmann, Kelly C. Weldon, Louis-Félix Nothias, Douglas Sweeney, Mingxun Wang, Paul R. Jensen, Letícia V. Costa-Lotufo, Christine Beemelmanns, Katherine R. Duncan, Nadine Ziemert, Xuanji Li, Dulce G. Guillén Matus, Chao Du, Neha Garg, Jae Seoun Hur, Elizabeth I. Parkinson, Raphael Reher, Nicholas J. Tobias, Alex A. Blacutt, Emily C Pierce, Michelle Schorn, J. Michael Beman, Simon Rogers, María Victoria Berlanga-Clavero, Martin Baunach, Fan Zhang, Deepa D. Acharya, Harald Gross, Hamada Saad, M. Caroline Roper, Anna Edlund, Jason M. Crawford, Daniel Petras, Alexandra Calteau, Benjamin-Florian Hempel, Seoung Rak Lee, Max Crüsemann, Neil L. Kelleher, Hosein Mohimani, David P. Fewer, Shaurya Chanana, Carmen Saenz, Lena Gerwick, Ki-Hyun Kim, Roderich D. Süssmuth, Jörn Piel, Diego Romero, Marnix H. Medema, Anelize Bauermeister, Christopher Drozd, Regan J. Thomson, Anne Boullie, Michael W. Mullowney, Karine Pires, Andrew C. McAvoy, Alexander A. Aksenov, Saefuddin Aziz, Raquel Castelo-Branco, Julia M. Gauglitz, Mitchell N. Muskat, Bart Cuypers, Emily C. Gentry, Yi Yuan Lee, Eric J. N. Helfrich, Tam Dang, Pieter C. Dorrestein, Liu Cao, Rachel J. Dutton, Gilles P. van Wezel, Helge B. Bode, Margherita Sosio, Asker Daniel Brejnrod, Gajender Aleti, Leonard Kaysser, Amaro E. Trindade-Silva, Willam W. Metcalf, Irina Koester, Tiago Leao, Katherine D. Bauman, Jessica C. Little, Evgenia Glukhov, Ellis C. O’Neill, Justin J. J. van der Hooft, Alyssa M. Demko, Alexander B. Chase, Marc G. Chevrette, Bradley S. Moore, Christian Martin H, Kapil Tahlan, Cameron R. Currie, Allegra T. Aron, Muriel Gugger, Kyo Bin Kang, Víctor J. Carrión, Michael J. Rust, Gabriele M. König, Carlos Molina-Santiago, Søren J. Sørensen, Marianna Iorio, Jean-Claude Dujardin, Daniel Männle, Chung Sub Kim, Laura M. Sanchez, Katherine N. Maloney, Stefan Verhoeven, Tristan de Rond

Publikováno v: Nature Chemical Biology
Nature Chemical Biology, Nature Publishing Group, 2021, ⟨10.1038/s41589-020-00724-z⟩
Nature Chemical Biology 17 (2021) 4
Nature Chemical Biology, 17(4), 363-368
Nature Chemical Biology, 17(4), 363-368. Nature Publishing Group
Nat Chem Biol
Schorn, M A, Verhoeven, S, Ridder, L, Huber, F, Acharya, D D, Aksenov, A A, Aleti, G, Moghaddam, J A, Aron, A T, Aziz, S, Bauermeister, A, Bauman, K D, Baunach, M, Beemelmanns, C, Beman, J M, Berlanga-Clavero, M V, Blacutt, A A, Bode, H B, Boullie, A, Brejnrod, A, Bugni, T S, Calteau, A, Cao, L, Carrión, V J, Castelo-Branco, R, Chanana, S, Chase, A B, Chevrette, M G, Costa-Lotufo, L V, Crawford, J M, Currie, C R, Cuypers, B, Dang, T, de Rond, T, Demko, A M, Dittmann, E, Du, C, Drozd, C, Dujardin, J-C, Dutton, R J, Edlund, A, Fewer, D P, Garg, N, Gauglitz, J M, Gentry, E C, Gerwick, L, Glukhov, E, Gross, H, Gugger, M, Matus, D G G, Helfrich, E J N, Hempel, B-F, Hur, J-S, Iorio, M, Jensen, P R, Kang, K B, Kaysser, L, Kelleher, N L, Kim, C S, Kim, K H, Koester, I, König, G M, Leao, T, Lee, S R, Lee, Y-Y, Li, X, Little, J C, Maloney, K N, Männle, D, Martin H., C, McAvoy, A C, Metcalf, W W, Mohimani, H, Molina-Santiago, C, Moore, B S, Mullowney, M W, Muskat, M, Nothias, L-F, O'Neill, E C, Parkinson, E I, Petras, D, Piel, J, Pierce, E C, Pires, K, Reher, R, Romero, D, Roper, M C, Rust, M, Saad, H, Saenz, C, Sanchez, L M, Sørensen, S J, Sosio, M, Süssmuth, R D, Sweeney, D, Tahlan, K, Thomson, R J, Tobias, N J, Trindade-Silva, A E, van Wezel, G P, Wang, M, Weldon, K C, Zhang, F, Ziemert, N, Duncan, K R, Crüsemann, M, Rogers, S, Dorrestein, P C, Medema, M H & van der Hooft, J J J 2021, ' A community resource for paired genomic and metabolomic data mining ', Nature Chemical Biology, vol. 17, no. 4, pp. 363-368 . https://doi.org/10.1038/s41589-020-00724-z
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Nature Chemical Biology, 2021, ⟨10.1038/s41589-020-00724-z⟩
Nature chemical biology

International audience; Genomics and metabolomics are widely used to explore specialized metabolite diversity. The Paired Omics Data Platform is a community initiative to systematically document links between metabolome and (meta)genome data, aiding

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28bab3cd944ad174c6905009e2841f0d
https://hal-pasteur.archives-ouvertes.fr/pasteur-03153704/document

Interaction of oxidative stress and neurotrauma in ALDH2 mice causes significant and persistent behavioral and pro-inflammatory effects in a tractable model of mild traumatic brain injury

Autor: Sue H. Lee, Yue-Ting Wang, Kevin A. Tam, Rachel C. Knopp, Gregory R. J. Thatcher, Manel BenAissa, Emily C Pierce, Daniyal Aamir, David Gonzalez, Emily Nepomuceno, Michael A. Hollas

Publikováno v: Redox Biology, Vol 32, Iss, Pp-(2020)

Oxidative stress induced by lipid peroxidation products (LPP) accompanies aging and has been hypothesized to exacerbate the secondary cascade in traumatic brain injury (TBI). Increased oxidative stress is a contributor to loss of neural reserve that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7645f362116446d61eb4404929993b5
https://doi.org/10.1016/j.redox.2020.101486