Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Emily C, Freund"'
Autor:
Anne L. Sapiro, Emily C. Freund, Lucas Restrepo, Huan-Huan Qiao, Amruta Bhate, Qin Li, Jian-Quan Ni, Timothy J. Mosca, Jin Billy Li
Publikováno v:
Cell Reports, Vol 31, Iss 7, Pp - (2020)
Summary: Adenosine-to-inosine RNA editing, catalyzed by adenosine deaminase acting on RNA (ADAR) enzymes, alters RNA sequences from those encoded by DNA. These editing events are dynamically regulated, but few trans regulators of ADARs are known in v
Externí odkaz:
https://doaj.org/article/1304ec9120344a938b611d234f8a9fe4
Autor:
Emily C. Freund, Anne L. Sapiro, Qin Li, Sandra Linder, James J. Moresco, John R. Yates, III, Jin Billy Li
Publikováno v:
Cell Reports, Vol 31, Iss 7, Pp - (2020)
Summary: Adenosine-to-inosine RNA editing is catalyzed by adenosine deaminase acting on RNA (ADAR) enzymes that deaminate adenosine to inosine. Although many RNA editing sites are known, few trans regulators have been identified. We perform BioID fol
Externí odkaz:
https://doaj.org/article/98102441b2a9423aa344b1d3f8811bfe
Autor:
Siri Tahtinen, Ann-Jay Tong, Patricia Himmels, Jaehak Oh, Andres Paler-Martinez, Leesun Kim, Sara Wichner, Yoko Oei, Mark J. McCarron, Emily C. Freund, Zhainib Adel Amir, Cecile C. de la Cruz, Benjamin Haley, Craig Blanchette, Jill M. Schartner, Weilan Ye, Mahesh Yadav, Ugur Sahin, Lélia Delamarre, Ira Mellman
Publikováno v:
Nature Immunology. 23:532-542
The use of lipid-formulated RNA vaccines for cancer or COVID-19 is associated with dose-limiting systemic inflammatory responses in humans that were not predicted from preclinical studies. Here, we show that the 'interleukin 1 (IL-1)-interleukin 1 re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::853754e3429271261548c4c29dc649ea
https://doi.org/10.1038/s41590-022-01160-y
https://doi.org/10.1038/s41590-022-01160-y
Publikováno v:
Methods in Molecular Biology ISBN: 9781071629376
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35d313677c69e1b3b0a59deb9ecc81a3
https://doi.org/10.1007/978-1-0716-2938-3_15
https://doi.org/10.1007/978-1-0716-2938-3_15
Autor:
Ira Mellman, Siri Tahtinen, Leesun Kim, Ugur Sahin, Patricia Himmels, Yoko Oei, Andres Paler-Martinez, Jill Schartner, Emily C. Freund, Craig Blanchette, Weilan Ye, Benjamin Haley, Ann-Jay Tong, Sara Wichner, Cecile de la Cruz, Jaehak Oh, Mahesh Yadav, Mark McCarron, Lélia Delamarre, Zhainib Adel Amir
Excessive systemic inflammation is characteristic to various acute conditions including sepsis, viral infections and immunotherapy-induced adverse events such as cytokine release syndrome (CRS). Recently, several clinical trials evaluating variants o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db2e7afb3cdd01228b8c45dad26e9d7b
https://doi.org/10.21203/rs.3.rs-378991/v1
https://doi.org/10.21203/rs.3.rs-378991/v1
Autor:
Emily C. Freund, Timurs Maculins, Aditya Murthy, Benjamin Haley, Jaclyn Y. Lock, Christopher J. Bohlen, Lélia Delamarre, Jaehak Oh
Publikováno v:
The Journal of Experimental Medicine
Highly efficient gene editing in primary myeloid cells is made possible by optimized non-viral delivery of CRISPR-Cas9. This enables single and multiplexed gene knockout in monocytes, macrophages, and dendritic cells to advance innate immunity resear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f93a692bc6ff3c495be2111379da057
http://europepmc.org/articles/PMC7336301
http://europepmc.org/articles/PMC7336301
Autor:
Jian-Quan Ni, Qin Li, Amruta Bhate, Anne L. Sapiro, Timothy J. Mosca, Lucas Restrepo, Huan-Huan Qiao, Emily C. Freund, Jin Billy Li
Publikováno v:
Cell Reports, Vol 31, Iss 7, Pp-(2020)
Cell reports
Cell reports
SUMMARY Adenosine-to-inosine RNA editing, catalyzed by adenosine deaminase acting on RNA (ADAR) enzymes, alters RNA sequences from those encoded by DNA. These editing events are dynamically regulated, but few trans regulators of ADARs are known in vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac04cbd34415b83f59b8b87a4d296457
http://www.sciencedirect.com/science/article/pii/S2211124720306070
http://www.sciencedirect.com/science/article/pii/S2211124720306070
Autor:
Alexander D, Gitlin, Klaus, Heger, Alexander F, Schubert, Rohit, Reja, Donghong, Yan, Victoria C, Pham, Eric, Suto, Juan, Zhang, Youngsu C, Kwon, Emily C, Freund, Jing, Kang, Anna, Pham, Roger, Caothien, Natasha, Bacarro, Trent, Hinkle, Min, Xu, Brent S, McKenzie, Benjamin, Haley, Wyne P, Lee, Jennie R, Lill, Merone, Roose-Girma, Monika, Dohse, Joshua D, Webster, Kim, Newton, Vishva M, Dixit
Publikováno v:
Nature. 587(7833)
Mutations in the death receptor FAS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::32a6433d04a9fdc12527bc4bd484234e
https://pubmed.ncbi.nlm.nih.gov/33106621
https://pubmed.ncbi.nlm.nih.gov/33106621
Autor:
Anne L. Sapiro, John R. Yates, Jin Billy Li, Sandra Linder, Emily C. Freund, James J. Moresco, Qin Li
Publikováno v:
Cell Reports, Vol 31, Iss 7, Pp-(2020)
Cell Rep
Cell Rep
Adenosine-to-Inosine RNA editing is catalyzed by ADAR enzymes that deaminate adenosine to inosine. While many RNA editing sites are known, few trans regulators have been identified. We perform BioID followed by mass-spectrometry to identify trans reg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d3233e20b8a8f4cb1b8b8038e21dfad
https://doi.org/10.1101/631200
https://doi.org/10.1101/631200