Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Emily Budziszewski"'
Publikováno v:
J Control Release
In situ forming implants (ISFIs) allow for a high initial intratumoral concentration and sustained release of the chemotherapeutic. However, clinical translation is impeded primarily due to limited drug penetration from the tumor/boundary interface a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b3e2b3f38d4f80996abbe2693752ba4
https://doi.org/10.1016/j.jconrel.2020.05.003
https://doi.org/10.1016/j.jconrel.2020.05.003
Autor:
Selva Jeganathan, Emily Budziszewski, Hanping Wu, Danielle Gilbert, Agata A. Exner, Christopher Hernandez, Sidhartha Tavri
Publikováno v:
ACS Biomaterials Science & Engineering. 5:1849-1856
In this study, we have developed a tunable polymer vascular embolic implant (TPVEI) with adjustable precipitation rates allowing for personalized, controlled vascular occlusion depths. We hypothesized that reducing the water miscibility of the solven
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87ae5f84e1de5aa2edc6901cc3c770c5
https://doi.org/10.1021/acsbiomaterials.8b01530
https://doi.org/10.1021/acsbiomaterials.8b01530
Autor:
Smriti Bohara, Emily Budziszewski, Agata A. Exner, Horst A. von Recum, Jackrit Suthakorn, Nathan A. Rohner
Publikováno v:
Ann Biomed Eng
This work demonstrates a slow, sustained drug delivery system that provides on-demand delivery bursts through the application of pulsed therapeutic ultrasound (TUS). Insoluble β-Cyclodextrin-polymer (pCD) disks were loaded with a saturated antibioti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed5f3da3fe534a91994446a9e1383fb8
https://europepmc.org/articles/PMC8458245/
https://europepmc.org/articles/PMC8458245/
Autor:
Emily Budziszewski, Selva Jeganathan, Michael C. Kolios, Agata A. Exner, Elizabeth S. L. Berndl
Publikováno v:
Visualizing and Quantifying Drug Distribution in Tissue IV.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5f0fa9f695128014f70a4ee34d354e5
https://doi.org/10.1117/12.2547061
https://doi.org/10.1117/12.2547061
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
P-glycoprotein (Pgp), a member of the ATP-binding cassette family, is one of the major causes of multidrug resistance in tumors. Current clinical treatments to overcome MDR involve the co-delivery of a Pgp inhibitor and a chemotherapeutic. A concern
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b8736ca29ecf70c2028180e1de189f1
https://pubmed.ncbi.nlm.nih.gov/32313056
https://pubmed.ncbi.nlm.nih.gov/32313056
Autor:
Agata A. Exner, Selva Jeganathan, Emily Budziszewski, Michael C. Kolios, Christopher Hernandez, Peter Bielecki
Publikováno v:
2018 IEEE International Ultrasonics Symposium (IUS).
Local drug delivery systems, such as in situ forming implants (ISFIs), allow for sustained elevated drug concentration directly at the tumor site. However, these systems have been challenging to translate into clinical practice due to poor drug penet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eac2034111e7fa15542e55cf03c6211f
https://doi.org/10.1109/ultsym.2018.8580108
https://doi.org/10.1109/ultsym.2018.8580108