Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Emily Brook"'
Autor:
Ryusuke Takechi, Arazu Sharif, Emily Brook, Maimuna Majimbi, Dick C. Chan, Virginie Lam, Gerald F. Watts, John C. L. Mamo
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
There is increasing evidence of a positive association of type 2 diabetes with Alzheimer’s disease (AD), the most prevalent form of dementia. Suggested pathways include cerebral vascular dysfunction; central insulin resistance, or exaggerated brain
Externí odkaz:
https://doaj.org/article/580703ccfe8447e7b3f3a4348b7307be
Autor:
Maimuna Majimbi, Emily Brook, Peter Galettis, Edward Eden, Hani Al-Salami, Armin Mooranian, Hesham Al-Sallami, Virginie Lam, John C L Mamo, Ryusuke Takechi
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0243858 (2021)
BackgroundCannabidiol (CBD) confers therapeutic effects in some neurological disorders via modulation of inflammatory, oxidative and cell-signalling pathways. However, CBD is lipophilic and highly photooxidative with low oral bioavailability in plasm
Externí odkaz:
https://doaj.org/article/058676ea48c849268a27fc0338581c06
Autor:
Ryusuke Takechi, Virginie Lam, Emily Brook, Corey Giles, Nicholas Fimognari, Armin Mooranian, Hani Al-Salami, Stephanie H. Coulson, Michael Nesbit, John C. L. Mamo
Publikováno v:
Frontiers in Aging Neuroscience, Vol 9 (2017)
Diabetic insulin resistance and pro-diabetic diet are reported to increase dementia risk through unknown mechanisms. Emerging evidence suggests that the integrity of blood-brain barrier (BBB) is central to the onset and progression of neurodegenerati
Externí odkaz:
https://doaj.org/article/4cc633c3426f4e18bb63395eaa4d9560
Autor:
Shelley Waters, Ashley Irish, Prue Howson, Jacquita S. Affandi, Christopher M. Reid, Patricia Price, Emily Brook, Hui Jun Chih, Silvia Lee
Publikováno v:
Journal of Medical Virology. 92:3650-3657
Cytomegalovirus (CMV) has been implicated in vascular pathologies and may warrant inclusion in cardiovascular predictive algorithms. We addressed this in healthy older adults and renal transplant recipients (RTR) as they retain a high burden of CMV.
Publikováno v:
npj Science of Learning, Vol 9, Iss 1, Pp 1-5 (2024)
Abstract We investigated if micro-consolidation, a phenomenon recently discovered during the brief rest periods between practice when learning an explicit motor sequence, generalises to learning an implicit motor sequence task. We demonstrate micro-c
Externí odkaz:
https://doaj.org/article/3d85cfbeb5a948598a59a51129d5c418
Autor:
Corey Giles, Mark J. Hackett, Michael Nesbit, Emily Brook, John C.L. Mamo, Blake J. Cochran, Maimuna Majimbi, Kerry-Anne Rye, Virginie Lam, Ryusuke Takechi, Ashley Hollings
Publikováno v:
ACS Chemical Neuroscience. 10:2533-2540
Non-insulin-dependent diabetes mellitus (NIDDM) is reported to increase the risk of cognitive impairment and dementia. However, the underlying mechanisms are not fully understood. While the brain homeostasis of metals and lipids is pivotal to maintai
Publikováno v:
Cancers, Vol 12, Iss 3483, p 3483 (2020)
Cancers
Cancers
Simple Summary The ongoing clinical need to improve cancer therapies warrants a better understanding of the mechanisms behind cancer growth and its spread to distant organs. To this end, research into the impact of sex hormones, such as oestrogens an
Autor:
Hesham S. Al-Sallami, Peter Galettis, Hani Al-Salami, Virginie Lam, Ryusuke Takechi, Emily Brook, John C.L. Mamo, Armin Mooranian, Edward Eden, Maimuna Majimbi
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 6, p e0243858 (2021)
PLoS ONE, Vol 16, Iss 6, p e0243858 (2021)
Background Cannabidiol (CBD) confers therapeutic effects in some neurological disorders via modulation of inflammatory, oxidative and cell-signalling pathways. However, CBD is lipophilic and highly photooxidative with low oral bioavailability in plas
Autor:
Armin Mooranian, John C.L. Mamo, Virginie Lam, Liam Graneri, Nicholas Fimognari, Zachary D'Alonzo, Michael Nesbit, Andrea Stephenson, Ryusuke Takechi, Hani Al-Salami, Emily Brook
Publikováno v:
Therapeutic Delivery. 9:703-709
Aim: To enhance the bioavailability and brain uptake of probucol and examine whether it attenuates neuroinflammation and neurodegeneration by utilizing a sodium alginate nanoencapsulation technique. Materials & methods: Wild-type mice were given eith
Publikováno v:
Free radical research. 53(11-12)
Since its discovery as a neurotrophic factor in retinal pigmented epithelium cells in the late 1980s, there has been an increase in understanding of the role that pigment epithelium-derived factor (PEDF) plays in cellular functions. PEDF plays an imp