Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Emily Bettini"'
Publikováno v:
STAR Protocols, Vol 3, Iss 4, Pp 101840- (2022)
Summary: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mRNA vaccines drive the generation of affinity-matured B cell responses through germinal center (GC) reactions in vaccine draining lymph nodes. Herein, we describe a procedure for
Externí odkaz:
https://doaj.org/article/d3eddff344264261b03d248e52b2cc37
Autor:
Qiong Xue, Emily Bettini, Patrick Paczkowski, Colin Ng, Alaina Kaiser, Timothy McConnell, Olja Kodrasi, Máire F. Quigley, James Heath, Rong Fan, Sean Mackay, Mark E. Dudley, Sadik H. Kassim, Jing Zhou
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 5, Iss 1, Pp 1-16 (2017)
Abstract Background It remains challenging to characterize the functional attributes of chimeric antigen receptor (CAR)-engineered T cell product targeting CD19 related to potency and immunotoxicity ex vivo, despite promising in vivo efficacy in pati
Externí odkaz:
https://doaj.org/article/ad391b0cd0634de0af9c0fb1b8b1b2e4
Autor:
Emily Bettini, Michela Locci
Publikováno v:
Vaccines, Vol 9, Iss 2, p 147 (2021)
To successfully protect against pathogen infection, a vaccine must elicit efficient adaptive immunity, including B and T cell responses. While B cell responses are key, as they can mediate antibody-dependent protection, T cells can modulate B cell ac
Externí odkaz:
https://doaj.org/article/4304d9f4e8ee4be6ab4f27c2cf7d9ca8
Autor:
Mohamad-Gabriel Alameh, István Tombácz, Emily Bettini, Katlyn Lederer, Sonia Ndeupen, Chutamath Sittplangkoon, Joel R. Wilmore, Brian T. Gaudette, Ousamah Y. Soliman, Matthew Pine, Philip Hicks, Tomaz B. Manzoni, James J. Knox, John L. Johnson, Dorottya Laczkó, Hiromi Muramatsu, Benjamin Davis, Wenzhao Meng, Aaron M. Rosenfeld, Shirin Strohmeier, Paulo J.C. Lin, Barbara L. Mui, Ying K. Tam, Katalin Karikó, Alain Jacquet, Florian Krammer, Paul Bates, Michael P. Cancro, Drew Weissman, Eline T. Luning Prak, David Allman, Botond Z. Igyártó, Michela Locci, Norbert Pardi
Publikováno v:
Immunity
Adjuvants are critical for improving the quality and magnitude of adaptive immune responses to vaccination. Lipid nanoparticle (LNP)-encapsulated nucleoside-modified mRNA vaccines have shown great efficacy against SARS-CoV-2, but the mechanism of act
Autor:
Katlyn Lederer, Emily Bettini, Kalpana Parvathaneni, Mark M. Painter, Divyansh Agarwal, Kendall A. Lundgreen, Madison Weirick, Kavitha Muralidharan, Diana Castaño, Rishi R. Goel, Xiaoming Xu, Elizabeth M. Drapeau, Sigrid Gouma, Jordan T. Ort, Moses Awofolaju, Allison R. Greenplate, Carole Le Coz, Neil Romberg, Jennifer Trofe-Clark, Gregory Malat, Lisa Jones, Mark Rosen, Daniela Weiskopf, Alessandro Sette, Behdad Besharatian, Mary Kaminiski, Scott E. Hensley, Paul Bates, E. John Wherry, Ali Naji, Vijay Bhoj, Michela Locci
Publikováno v:
Cell
medRxiv
medRxiv
Vaccine-mediated immunity often relies on the generation of protective antibodies and memory B cells, which commonly stem from germinal center (GC) reactions. An in-depth comparison of the GC responses elicited by SARS-CoV-2 mRNA vaccines in healthy
Autor:
Jason Palladino, David M. Glover, Rachel J. O’Neill, Marcin R. Przewloka, Barbara G. Mellone, Leah Rosin, Emily Bettini, Sarah Trusiak, Zoltán Lipinszki, Sarion R. Bowers, Chin-Chi Chen
Publikováno v:
Developmental cell. 34(1)
SummaryCentromeres are essential chromosomal structures that mediate accurate chromosome segregation during cell division. Centromeres are specified epigenetically by the heritable incorporation of the centromeric histone H3 variant CENP-A. While man
Autor:
Barbara G. Mellone, Karolin Luger, Mekonnen Lemma Dechassa, Patrick Heun, Chin-Chi Chen, Emily Bettini, Christian Belisario, Mary B. Ledoux
Publikováno v:
Chen, C-C, Dechassa, M L, Bettini, E, Ledoux, M B, Belisario, C, Heun, P, Luger, K & Mellone, B G 2014, ' CAL1 is the Drosophila CENP-A assembly factor ', Journal of Cell Biology, vol. 204, no. 3, pp. 313-29 . https://doi.org/10.1083/jcb.201305036
The Journal of Cell Biology
The Journal of Cell Biology
Representing a unique family of histone assembly factors, CAL1 assembles the histone H3 variant CENP-A on centromeric DNA in Drosophila.
Centromeres are specified epigenetically by the incorporation of the histone H3 variant CENP-A. In humans, a
Centromeres are specified epigenetically by the incorporation of the histone H3 variant CENP-A. In humans, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::803c4d5ec4d37a647c6aef019ccaec6b
https://hdl.handle.net/20.500.11820/b12ad0b0-b5f0-46a9-b755-be65bc321b69
https://hdl.handle.net/20.500.11820/b12ad0b0-b5f0-46a9-b755-be65bc321b69