Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Emily B, Martin"'
Autor:
Trevor J. Hancock, Marina Vlasyuk, James S. Foster, Sallie Macy, Daniel C. Wooliver, Manasi Balachandran, Angela D. Williams, Emily B. Martin, Stephen J. Kennel, Eric R. Heidel, Jonathan S. Wall, Joseph W. Jackson
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionAmyloid-specific antibodies have been shown to opsonize and enhance amyloid clearance in systemic amyloidosis mouse models. However, the immunological mechanisms by which amyloid is removed have not been clearly defined. Previous reports
Externí odkaz:
https://doaj.org/article/4538e96b6e1444728c5563af79f43964
Autor:
James S. Foster, Manasi Balachandran, Trevor J. Hancock, Emily B. Martin, Sallie Macy, Craig Wooliver, Tina Richey, Alan Stuckey, Angela D. Williams, Joseph W. Jackson, Stephen J. Kennel, Jonathan S. Wall
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionSystemic amyloidosis is a progressive disorder characterized by the extracellular deposition of amyloid fibrils and accessory proteins in visceral organs and tissues. Amyloid accumulation causes organ dysfunction and is not generally clea
Externí odkaz:
https://doaj.org/article/3ce636148a204e3aafd0f0efaec0fd54
Autor:
Emily B. Martin, Alan Stuckey, Dustin Powell, Ronald Lands, Bryan Whittle, Craig Wooliver, Sallie Macy, James S. Foster, Spencer Guthrie, Stephen J. Kennel, Jonathan S. Wall
Publikováno v:
Pharmaceuticals, Vol 16, Iss 4, p 629 (2023)
There are at least 20 distinct types of systemic amyloidosis, all of which result in the organ-compromising accumulation of extracellular amyloid deposits. Amyloidosis is challenging to diagnose due to the heterogeneity of the clinical presentation,
Externí odkaz:
https://doaj.org/article/0c7a66e5b85e4db4a58eeeaf99099fad
Autor:
Joseph W. Jackson, James S. Foster, Emily B. Martin, Sallie Macy, Craig Wooliver, Manasi Balachandran, Tina Richey, R. Eric Heidel, Angela D. Williams, Stephen J. Kennel, Jonathan S. Wall
Publikováno v:
Amyloid. :1-12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd06c6460612ca06556a2071d6bbb6f9
https://doi.org/10.1080/13506129.2022.2155133
https://doi.org/10.1080/13506129.2022.2155133
Autor:
Emily B. Martin, Angela Williams, Tina Richey, Craig Wooliver, Alan Stuckey, James S. Foster, Stephen J. Kennel, Jonathan S. Wall
Publikováno v:
Journal of Translational Medicine, Vol 15, Iss 1, Pp 1-11 (2017)
Abstract Background Systemic amyloidoses comprise diseases characterized by the deposition of proteinaceous material known as amyloid. Currently, without performing multiple biopsies, there is no way to ascertain the extent of amyloid deposition in p
Externí odkaz:
https://doaj.org/article/557423129c224980958d264ad5096d06
Autor:
Ronald H. Lands, Michael G. Stabin, Dustin Powell, Bryan Whittle, Aaron Endsley, Alan Stuckey, Ryan R. Julian, Tyler R. Lambeth, Emily B. Martin, Stephen J. Kennel, Angela Williams, Jonathan S. Wall, Sarah Hall
Publikováno v:
Molecular Imaging and Biology. 24:479-488
Purpose Accurate diagnosis of amyloidosis remains a significant clinical challenge and unmet need for patients. The amyloid-reactive peptide p5+14 radiolabeled with iodine-124 has been developed for the detection of amyloid by PET/CT imaging. In a fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36afe720dfd02194efcd85765f374692
https://doi.org/10.1007/s11307-021-01681-2
https://doi.org/10.1007/s11307-021-01681-2
Autor:
Jonathan S. Wall, Emily B. Martin, Tina Richey, Alan C. Stuckey, Sallie Macy, Craig Wooliver, Angela Williams, James S. Foster, Penney McWilliams-Koeppen, Ed Uberbacher, Xiaolin Cheng, Stephen J. Kennel
Publikováno v:
Molecules, Vol 20, Iss 5, Pp 7657-7682 (2015)
Amyloid is a complex pathologic matrix comprised principally of paracrystalline protein fibrils and heparan sulfate proteoglycans. Systemic amyloid diseases are rare, thus, routine diagnosis is often challenging. The glycosaminoglycans ubiquitously p
Externí odkaz:
https://doaj.org/article/599fcb02977e46dc8ccd340512015f8d
Autor:
James S. Foster, Angela D. Williams, Sallie Macy, Tina Richey, Alan Stuckey, Daniel Craig Wooliver, Richa Koul-Tiwari, Emily B. Martin, Stephen J. Kennel, Jonathan S. Wall
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
There is a continuing need for therapeutic interventions for patients with the protein misfolding disorders that result in systemic amyloidosis. Recently, specific antibodies have been employed to treat AL amyloidosis by opsonizing tissue amyloid dep
Externí odkaz:
https://doaj.org/article/77898dc3ab4441cdbcb2ebfc9ee72ae6
Publikováno v:
Molecular Imaging, Vol 16 (2017)
Amyloidosis is associated with a number of rare diseases and is characterized by the deposition, in abdominothoracic organs and peripheral nerves, of extracellular protein fibrils, which leads to dysfunction and severe morbidity. Effective clinical e
Externí odkaz:
https://doaj.org/article/14ecb53894044f948c61b7b1618f51d9
Autor:
Emily B Martin, Angela Williams, Craig Wooliver, R Eric Heidel, Sarah Adams, John Dunlap, Marina Ramirez-Alvarado, Luis M Blancas-Mejia, Ronald H Lands, Stephen J Kennel, Jonathan S Wall
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0174152 (2017)
BACKGROUND:Monoclonal free light chain (LC) proteins are present in the circulation of patients with immunoproliferative disorders such as light chain (AL) amyloidosis and multiple myeloma (MM). Light chain-associated amyloid is a complex pathology c
Externí odkaz:
https://doaj.org/article/70a1e18a6c244bd991809094f706fbdf