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pro vyhledávání: '"Emily Astarita"'
Publikováno v:
Cancer Research. 81:PS16-21
Adenomatous Polyposis Coli (APC) is a multi-domain tumor suppressor with multiple binding partners, including β-catenin, axin, and microtubules. APC is lost in many epithelial cancers, including up to 70% of sporadic breast cancers, with a tendency
Autor:
T. Murlidharan Nair, Sara M. Maloney, Monica K. VanKlompenberg, Bronwyn J. Berkeley, Emily Astarita, Jenifer R. Prosperi, Camden A. Hoover
Publikováno v:
PLoS ONE, Vol 16, Iss 8 (2021)
PLoS ONE
PLoS ONE, Vol 16, Iss 8, p e0255738 (2021)
PLoS ONE
PLoS ONE, Vol 16, Iss 8, p e0255738 (2021)
Adenomatous Polyposis Coli (APC) is lost in approximately 70% of sporadic breast cancers, with an inclination towards triple negative breast cancer (TNBC). TNBC is treated with traditional chemotherapy, such as paclitaxel (PTX); however, tumors often
Adenomatous Polyposis Coli (APC) is lost in approximately 70% of sporadic breast cancers, with an inclination towards triple negative breast cancer (TNBC). TNBC is treated with traditional chemotherapy, such as paclitaxel (PTX); however, tumors often
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0803ebe51d4854421a802128f416eef7
https://doi.org/10.1101/2020.10.31.362608
https://doi.org/10.1101/2020.10.31.362608
Publikováno v:
Proceedings of IMPRS. 2
Background and Hypothesis: A majority of sporadic breast cancers include deficits in the expression of Adenomatous Polyposis Coli (APC), a tumor suppressor. Deficits in APC are more common in patients with TNBC (triple negative breast cancer), which
Publikováno v:
Cancer Research. 79:3821-3821
Adenomatous Polyposis Coli (APC) is a multi-domain tumor suppressor protein that binds to proteins including β-catenin, axin, and microtubules (MTs). APC is lost in many epithelial cancers and up to 70% of sporadic breast cancers, with a tendency to