Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Emily A. York"'
Autor:
Patrick Stoiber, Pietro Scribani Rossi, Niranjana Pokharel, Jean-Luc Germany, Emily A. York, Scott E. Schaus, Ulla Hansen
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Factor quinolinone inhibitors are promising anti-cancer compounds, initially characterized as specific inhibitors of the oncogenic transcription factor LSF (TFCP2). These compounds exert anti-proliferative activity at least in part by disrup
Externí odkaz:
https://doaj.org/article/17bb4586a609471589a4fe4bbe029ae8
Autor:
Sarah A. Yunes, Jennifer L. S. Willoughby, Julian H. Kwan, Jessica M. Biagi, Niranjana Pokharel, Hang Gyeong Chin, Emily A. York, Kuan-Chung Su, Kelly George, Jagesh V. Shah, Andrew Emili, Scott E. Schaus, Ulla Hansen
Publikováno v:
PLoS ONE, Vol 17, Iss 6 (2022)
Factor quinolinone inhibitors (FQIs), a first-in-class set of small molecule inhibitors targeted to the transcription factor LSF (TFCP2), exhibit promising cancer chemotherapeutic properties. FQI1, the initial lead compound identified, unexpectedly i
Externí odkaz:
https://doaj.org/article/6ae848c8bada4a1bafa17d2db5c202d0
Autor:
Saran Lotfollahzadeh, Dominic Lo, Emily A. York, Marc A. Napoleon, Wenqing Yin, Nagla Elzinad, John Le, Mengwei Zhang, Xiaosheng Yang, Austin Morrissey, Murad Elsadawi, Qing Zhao, Scott E. Schaus, Ulla Hansen, Vipul C. Chitalia
Publikováno v:
The American journal of pathology. 192(8)
Aberrant hyperactivation of Wnt signaling, driven by nuclear β-catenin in the colonic epithelium, represents the seminal event in the initiation and progression of colorectal cancer (CRC). Despite its established role in CRC tumorigenesis, clinical
Autor:
Emily A York, Matthew Cahillane, Colleen E Moran, Elena Grossman, Kathleen F. Bush, Samuel Dorevitch, Michelle Hathaway, Dorette Q English, Christopher K. Uejio, Tisha Holmes
Publikováno v:
Journal of Public Health Management and Practice. 25:113-120
Context Human health is threatened by climate change. While the public health workforce is concerned about climate change, local health department (LHD) administrators have reported insufficient knowledge and resources to address climate change. Mini
Preselection of Lung Cancer Cases Using FGFR1 mRNA and Gene Copy Number for Treatment With Ponatinib
Autor:
D. Ross Camidge, Derek E. Smith, Dara L. Aisner, Adrie van Bokhoven, Theresa A. Boyle, Dexiang Gao, Hui Yu, Emily R. York, Scott Leedy, Lynn E. Heasley, Terry L. Ng, Fred R. Hirsch
Publikováno v:
Clinical Lung Cancer. 20:e39-e51
Introduction Preclinically, high epidermal growth factor receptor 1 (FGFR1) messenger RNA (FGFR1-MRNA) and FGFR1 amplification (FGFR1-AMP) predicted sensitivity to fibroblast growth factor receptor inhibitors in non–small-cell lung cancer and small
Publikováno v:
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 12(7)
Publikováno v:
Emerging Infectious Diseases, Vol 21, Iss 7, Pp 1234-1236 (2015)
Emerging Infectious Diseases
Emerging Infectious Diseases
Using quantitative PCR analysis and DNA sequencing, we provide evidence for the presence of rat lungworm (Angiostrongylus cantonensis) in Oklahoma, USA, and identified a potentially novel rat host (Sigmodon hispidus). Our results indicate a geographi
Preselection of lung cancer cases using FGFR1 mRNA and gene copy number for treatment with ponatinib
Autor:
Scott Leedy, D. Ross Camidge, Hui Yu, Emily R. York, Dexiang Gao, Derek E. Smith, Theresa A. Boyle, Lynn E. Heasley, Terry L. Ng, Fred R. Hirsch
Publikováno v:
Journal of Clinical Oncology. 36:12095-12095
12095Background: NSCLC and SCLC cell line data suggested high FGFR1 mRNA levels and FGFR1 amplification (FGFR1-AMP) could predict sensitivity to FGFR TKIs. Overlap with KRAS mutations did not precl...
Autor:
Melissa B. Collins, Derren T. Rosbach, Sean P. O'Connell, Kristina Reid Black, Weaver B. Haney, Emily A. York
Publikováno v:
Southeastern Naturalist. 6:57-72
Soils and waters were collected from Great Smoky Mountains National Park (GSMNP), and bacteria were cultured or DNA cloned from the samples. Oconaluftee Visitors Center and Kephart Prong Trail were sampled to examine distributions of heterotrophs inh
Publikováno v:
Carbohydrate polymers. 133
We describe the first synthesis of hydroxy-functionalized polysaccharide esters via chemoselective olefin hydroboration-oxidation in the presence of ester groups. Cellulose esters with terminally olefinic side chains were first synthesized by esterif