Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Emily A. Stander"'
Autor:
Emily Amor Stander, Beata Lehka, Inês Carqueijeiro, Clément Cuello, Frederik G. Hansson, Hans J. Jansen, Thomas Dugé De Bernonville, Caroline Birer Williams, Valentin Vergès, Enzo Lezin, Marcus Daniel Brandbjerg Bohn Lorensen, Thu-Thuy Dang, Audrey Oudin, Arnaud Lanoue, Mickael Durand, Nathalie Giglioli-Guivarc’h, Christian Janfelt, Nicolas Papon, Ron P. Dirks, Sarah Ellen O’connor, Michael Krogh Jensen, Sébastien Besseau, Vincent Courdavault
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-19 (2023)
Abstract Monoterpene indole alkaloids (MIAs) are a structurally diverse family of specialized metabolites mainly produced in Gentianales to cope with environmental challenges. Due to their pharmacological properties, the biosynthetic modalities of se
Externí odkaz:
https://doaj.org/article/60239ee0c7994813904a74c32f5c4947
Autor:
Sarah Ellen O'Connor, Sébastien Besseau, Ron P. Dirks, Michael Krogh Jensen, Arnaud Lanoue, Nathalie Giglioli Guivarc'h, Audrey Oudin, Caroline Birer Williams, Hans J. Jansen, Thomas Dugé De Bernonville, Clément Cuello, Emily Amor Stander, Nicolas Papon, Vincent Courdavault
Publikováno v:
F1000Research, Vol 11 (2022)
The Madagascar periwinkle, Catharanthus roseus, belongs to the Apocynaceae family. This medicinal plant, endemic to Madagascar, produces many important drugs including the monoterpene indole alkaloids (MIA) vincristine and vinblastine used to treat c
Externí odkaz:
https://doaj.org/article/fd8bb44b1ec54c25a59a9cf3f78f3281
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 3659-3663 (2021)
Camptothecin is a clinically important monoterpene indole alkaloid (MIAs) used for treating various cancers. Currently, the production of this biopharmaceutical hinges on its extraction from camptothecin-producing plants, leading to high market price
Externí odkaz:
https://doaj.org/article/602141624b9b47bcb08981d35f85c82f
Autor:
Pamela Lemos Cruz, Ines Carqueijeiro, Konstantinos Koudounas, Dikki Pedenla Bomzan, Emily Amor Stander, Cécile Abdallah, Natalja Kulagina, Audrey Oudin, Arnaud Lanoue, Nathalie Giglioli-Guivarc’h, Dinesh A Nagegowda, Nicolas Papon, Sébastien Besseau, Marc Clastre, Vincent Courdavault
Publikováno v:
Protoplasma. 260:607-624
The medicinal plant Catharanthus roseus biosynthesizes many important drugs for human health, including the anticancer monoterpene indole alkaloids (MIAs) vinblastine and vincristine. Over the past decades, the continuous increase in pharmaceutical d
Autor:
Emily Amor Stander, Liuda Johana Sepúlveda, Thomas Dugé de Bernonville, Inês Carqueijeiro, Konstantinos Koudounas, Pamela Lemos Cruz, Sébastien Besseau, Arnaud Lanoue, Nicolas Papon, Nathalie Giglioli-Guivarc’h, Ron Dirks, Sarah Ellen O’Connor, Lucia Atehortùa, Audrey Oudin, Vincent Courdavault
Publikováno v:
Biomolecules, Vol 10, Iss 12, p 1595 (2020)
The lesser periwinkle Vinca minor accumulates numerous monoterpene indole alkaloids (MIAs) including the vasodilator vincamine. While the biosynthetic pathway of MIAs has been largely elucidated in other Apocynaceae such as Catharanthus roseus, the c
Externí odkaz:
https://doaj.org/article/b8374e5797594eed9a42d3fa2806a3ea
Autor:
Clément, Cuello, Emily Amor, Stander, Hans J, Jansen, Thomas, Dugé de Bernonville, Arnaud, Lanoue, Nathalie, Giglioli-Guivarc'h, Nicolas, Papon, Ron P, Dirks, Michael Krogh, Jensen, Sarah Ellen, O'Connor, Sébastien, Besseau, Vincent, Courdavault
Publikováno v:
Genome biology and evolution. 14(11)
The Apocynaceae tree Voacanga thouarsii, native to southern Africa and Madagascar, produces monoterpene indole alkaloids (MIA), which are specialized metabolites with a wide range of bioactive properties. Voacanga species mainly accumulates tabersoni
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2505
Increased affordability and availability of high-throughput next-generation sequencing (NGS) technologies have resulted in an explosion of available RNA-seq data, igniting a variety of data-mining methodologies, valuable for plant-specialized biosynt
Autor:
Thomas, Dugé de Bernonville, Emily, Amor Stander, Géraud, Dugé de Bernonville, Sébastien, Besseau, Vincent, Courdavault
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2505
Elucidation of biological pathways leading to specialized metabolites remains a complex task. It is however a mandatory step to allow bioproduction into heterologous hosts. Many steps have already been identified using conventional approaches, enlarg
Autor:
Emily Amor Stander, Wesley Williams, Fanie Rautenbach, Marilize Le Roes-Hill, Yamkela Mgwatyu, Jeanine Marnewick, Uljana Hesse
Publikováno v:
Molecules, Vol 24, Iss 5, p 938 (2019)
Aspalathin, the main polyphenol of rooibos (Aspalathus linearis), is associated with diverse health promoting properties of the tea. During fermentation, aspalathin is oxidized and concentrations are significantly reduced. Standardized methods for qu
Externí odkaz:
https://doaj.org/article/d5174f76a5d449598614dc31d6f4211e
Autor:
Emily Amor, Stander, Clément, Cuello, Caroline, Birer-Williams, Natalja, Kulagina, Hans J, Jansen, Ines, Carqueijeiro, Louis-Valentin, Méteignier, Valentin, Vergès, Audrey, Oudin, Nicolas, Papon, Ron P, Dirks, Michael Krogh, Jensen, Sarah Ellen, O'Connor, Thomas, Dugé de Bernonville, Sébastien, Besseau, Vincent, Courdavault
Publikováno v:
G3 (Bethesda, Md.). 12(12)
Vinca minor, also known as the lesser periwinkle, is a well-known species from the Apocynaceae, native to central and southern Europe. This plant synthesizes monoterpene indole alkaloids, which are a class of specialized metabolites displaying a wide