Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Emily A. Reiff"'
Publikováno v:
Anesthesiology Research and Practice, Vol 2020 (2020)
Background. The most common complication after cesarean delivery is surgical site infection. Antibiotic prophylaxis reduces infectious morbidity and current anesthetic quality metrics include preincision antibiotic prophylaxis. Recently, studies sugg
Externí odkaz:
https://doaj.org/article/fec5a8a08ae94e28af7ac310f8219319
Autor:
Rossano Lucius T, Michael A. Schmidt, Vu Chi Truc, Jacob Albrecht, Andrew G. Lee, Xinhua Qian, Ehrlic Lo, Steven L. Goldberg, Emily A. Reiff, Jaan A. Pesti, Chao Hang, Kenneth J. Natalie, Animesh Goswami, Zhiwei Guo, Chenchi Wang
Publikováno v:
Organic Process Research & Development. 19:1317-1322
The process development and large scale synthesis for the β-hydroxyamino amide 1 is described. The route evolved from a multistep sequence utilizing a classical resolution to a two-step enantioselective process involving an enzyme-catalyzed aldol re
Autor:
Sarah C, Lassey, Emily S, Reiff, Lori, Dobson, Bryann, Bromley, Louise, Wilkins-Haug, Deborah, Bartz, Sarah E, Little
Publikováno v:
Prenatal diagnosis. 37(7)
The objective of this study is to compare the gestational age at termination for trisomy 13, 18, or 21 (aneuploidy) before and after the introduction of noninvasive prenatal testing (NIPT).A retrospective cohort of women undergoing termination for an
Autor:
Emily A. Reiff, Michael E. Kopach
Publikováno v:
Future Medicinal Chemistry. 4:1395-1398
Publikováno v:
Organic Process Research & Development. 16:567-576
This work presents a process modeling-based methodology towards quality by design that was applied throughout the development lifecycle of the ibipinabant API step. By combining mechanistic kinetic modeling with fundamental thermodynamics, the degrad
Autor:
Sunil A. David, Gunda I. Georg, David Vander Velde, John T. Henri, Richard H. Himes, Sajiv K. Nair, Ting Lan Chiu, Bollu S. Reddy, Ramappa Chakrasali, Elizabeth A. Amin, Emily A. Reiff, Jack F. Greiner
Publikováno v:
The Journal of Organic Chemistry. 75:86-94
Three photoaffinity labeled derivatives of epothilone D were prepared by total synthesis, using efficient novel asymmetric synthesis methods for the preparation of two important synthetic building blocks. The key step for the asymmetric synthesis of
Autor:
Hanumaiah Telikepalli, Douglas R. Powell, Mary L. Michaelis, Emily A. Reiff, Gunda I. Georg, Sabah Ansar, Kelly E. Desino, Kenneth L. Audus, Richard H. Himes
Publikováno v:
Journal of Medicinal Chemistry. 52:7537-7543
Compounds that interact with microtubules, such as paclitaxel, have been shown to possess protective properties against beta-amyloid (Abeta) induced neurodegeneration associated with Alzheimer's disease. In this work, the novel agent (3R,5S,7as)-(3,5
Autor:
Derek Berglund, Jeffrey T. Bien, John Wasylak, Purushotham Vemishetti, David J. Kacsur, Jun Qiu, Oscar W. Haas, Chien-Kuang Chen, Yeung Y. Chan, Carrie A. Costello, Lori Spangler, Emily A. Reiff, Jale Muslehiddinoglu, Dale Vanyo, Stephane Gingras, Jaan A. Pesti, Nina Nguyen, Albert J. DelMonte, John A. Grosso, Chiajen Lai, Simon Leung, Wendel W. Doubleday, Michael J. Totleben, Paul Demena, Elisabeth Corbett, Martina Olzog, Dominique Thoraval, Serge Benoit, Melanie Miller, Robert P. Discordia, Zhinong Gao, Paul R. Brodfuehrer, Chenkou Wei
Publikováno v:
Organic Process Research & Development. 13:716-728
The development of a safe, robust process for the preparation of ravuconazole (1), an antifungal agent, is described. The discovery and development of procedures enabling the efficient synthesis of multikilogram quantities of 1 and the process demons
Autor:
David VanderVelde, Sajiv K. Nair, Gunda I. Georg, Richard H. Himes, Emily A. Reiff, Oliver E. Hutt, Jack F. Greiner, Bollu S. Reddy, Jun Inagaki, Elizabeth A. Amin, Ting Lan Chiu, John T. Henri
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 19:3293-3296
The total synthesis of 22-(3-azidobenzoyloxy)methyl epothilone C is described as a potential photoaffinity probe to elucidate the beta-tubulin binding site. A sequential Suzuki-aldol-Yamaguchi macrolactonization strategy was utilized employing a nove
Publikováno v:
Prenatal diagnosis. 36(3)
This study aimed to examine the role of the 11- to 14-week ultrasound in women with negative cell-free DNA screening.A retrospective cohort study of women at increased risk for aneuploidy based on age or medical history and negative cell-free DNA scr