Výsledky vyhledávání - "Emily A. Pena"

Elevated levels of Interleukin (IL)-33 induce bone pathology but absence of IL-33 does not negatively impact normal bone homeostasis

Autor: Heather A Bullock, Hana E. Baker, Matthew J Hamang, Angela J. Okragly, Y. Linda Ma, Jonathan Lucchesi, Andrea P. Martin, Robert J. Benschop, Emily A. Pena

Publikováno v: Cytokine. 79:66-73

Interleukin (IL)-33 is a member of the IL-1 family. IL-33 effects are mediated through its receptor, ST2 and IL-1RAcP, and its signaling induces the production of a number of pro-inflammatory mediators, including TNFα, IL-1β, IL-6, and IFN-γ. Ther

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd157d890590f7f760e190b5dfba072e
https://doi.org/10.1016/j.cyto.2015.12.011

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Thermodynamics of binding by calmodulin correlates with target peptide α-helical propensity

Autor: Jessime Kirk, Trevor P. Creamer, Meghan H. Yoder, Tori B. Dunlap, Emily A. Pena

Publikováno v: Proteins. 81(4)

In this work, we have examined contributions to the thermodynamics of calmodulin (CaM) binding from the intrinsic propensity for target peptides to adopt an α-helical conformation. CaM target sequences are thought to commonly reside in disordered re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2784dd05f98ff57d665e556a3a435def
https://pubmed.ncbi.nlm.nih.gov/23180611

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