Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Emily A. Mcmillan"'
Autor:
Masaru Sasaki, Takeo Hara, Joshua X. Wang, Yusen Zhou, Kanak V. Kennedy, Chizoba N. Umeweni, Maiya A. Alston, Zachary C. Spergel, Satoshi Ishikawa, Ryugo Teranishi, Ritsu Nakagawa, Emily A. Mcmillan, Kelly A. Whelan, Tatiana A. Karakasheva, Kathryn E. Hamilton, Melanie A. Ruffner, Amanda B. Muir
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 17, Iss 6, Pp 923-937 (2024)
Background & Aims: Epithelial disruption in eosinophilic esophagitis (EoE) encompasses both impaired differentiation and diminished barrier integrity. We have shown that lysyl oxidase (LOX), a collagen cross-linking enzyme, is up-regulated in the eso
Externí odkaz:
https://doaj.org/article/4642d52f7d81435797854e2d8c616673
Autor:
Louis R. Parham, Patrick A. Williams, Kay Katada, Shaneice K. Nettleford, Priya Chatterji, Kofi K. Acheampong, Charles H. Danan, Xianghui Ma, Lauren A. Simon, Kaitlyn E. Naughton, Rei Mizuno, Tatiana Karakasheva, Emily A. McMillan, Kelly A. Whelan, Donita C. Brady, Sydney M. Shaffer, Kathryn E. Hamilton
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 17, Iss 3, Pp 439-451 (2024)
Background & Aims: The intestinal epithelium interfaces with a diverse milieu of luminal contents while maintaining robust digestive and barrier functions. Facultative intestinal stem cells are cells that survive tissue injury and divide to re-establ
Externí odkaz:
https://doaj.org/article/2d55833f363e489b8c29b533990b04ea
Autor:
Patrick A. Williams, Kaitlyn E. Naughton, Lauren A. Simon, Gloria E. Soto, Louis R. Parham, Xianghui Ma, Charles H. Danan, Weiming Hu, Elliot S. Friedman, Emily A. McMillan, Hritik Mehta, Madison A. Stoltz, Joshua Soto Ocaña, Joseph P. Zackular, Kyle Bittinger, Kelly A. Whelan, Tatiana A. Karakasheva, Kathryn E. Hamilton
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 324:G354-G368
Calorie restriction is associated with enhanced intestinal regeneration after irradiation, but the requirement of autophagy for this process is not known. Our data support the premise that intestinal epithelial autophagy is required for the regenerat
Autor:
Charles H. Danan, Kaitlyn E. Naughton, Katharina E. Hayer, Sangeevan Vellappan, Emily A. McMillan, Yusen Zhou, Rina Matsuda, Shaneice K. Nettleford, Kay Katada, Louis R. Parham, Xianghui Ma, Afrah Chowdhury, Benjamin J. Wilkins, Premal Shah, Matthew D. Weitzman, Kathryn E. Hamilton
Intestinal epithelial transit amplifying cells are essential stem progenitors required for intestinal homeostasis, but their rapid proliferation renders them vulnerable to DNA damage from radiation and chemotherapy. Despite their critical roles in in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6ba4e1d29349598369deb0938fa2c80
https://doi.org/10.1101/2023.04.06.535853
https://doi.org/10.1101/2023.04.06.535853
Autor:
Louis R. Parham, Patrick A. Williams, Priya Chatterji, Kofi K. Acheampong, Charles H. Danan, Kay Katada, Xianghui Ma, Lauren A. Simon, Kaitlyn E. Naughton, Rei Mizuno, Tatiana Karakasheva, Emily A. McMillan, Kelly A. Whelan, Donita C. Brady, Sydney M. Shaffer, Kathryn E. Hamilton
Homeostatic tissue maintenance requires coordinated regulation of metabolic processes including macroautophagy/autophagy. Autophagy dysregulation underlies numerous human diseases. Our prior work revealed that the RNA binding protein IGF2BP1/IMP1 bin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e81235c991a2c078f486f90778a5711
https://doi.org/10.1101/2022.02.28.482365
https://doi.org/10.1101/2022.02.28.482365
Publikováno v:
International Journal of Speleology, Vol 36, Iss 2, Pp 69-74 (2007)
Calcareous speleothems provide a record of dripwater composition which in turn is a function of climatic conditions. The historical focus of speleothem palaeoclimate studies has been on the derivation of palaeotemperatures through oxygen isotope stud
Externí odkaz:
https://doaj.org/article/8f4cfd4563c442d6a242133bb5d772e0
Publikováno v:
Cell Stress Chaperones
Developing male germ cells are extremely sensitive to heat stress; consequently, anatomic and physiologic adaptations have evolved to maintain proper thermoregulation during mammalian spermatogenesis. At the cellular level, increased expression and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c8a1921134a904d24821072049d42be
https://europepmc.org/articles/PMC6882973/
https://europepmc.org/articles/PMC6882973/
Autor:
Nisha K. Singh, Baicheng Lin, Emily A. McMillan, Sheila M. Longo, Todd I. Strochlic, Michael D. Smith, Sarah A Broskin
Publikováno v:
Journal of Biological Chemistry. 293:2990-3002
Lipid metabolism plays a critical role in female reproduction. During oogenesis, maturing oocytes accumulate high levels of neutral lipids that are essential for both energy production and the synthesis of other lipid molecules. Metabolic pathways wi
Autor:
P. Bonnand, Michael J. Hambrey, Edward J. Fleming, Nathalie Grassineau, Ian J. Parkinson, Emily M. McMillan, Tesni Davies, Ian J. Fairchild, Galen P. Halverson, Carl Stevenson, Elizabeth McKay
Publikováno v:
Fairchild, I J, Bonnand, P, Davies, T, Fleming, E J, Grassineau, N, Halverson, G P, Hambrey, M J, McMillan, E M, McKay, E, Parkinson, I J & Stevenson, C T E 2016, ' The Late Cryogenian Warm Interval, NE Svalbard : Chemostratigraphy and genesis ', Precambrian Research, vol. 281, pp. 128-154 . https://doi.org/10.1016/j.precamres.2016.05.013
The Late Cryogenian Warm Interval (LCWI) refers to a non-glacial interval that separates presumed representatives of the Sturtian and Marinoan panglaciations. Its duration is poorly constrained radiometrically and its deposits are relatively poorly k
Publikováno v:
Journal of visualized experiments : JoVE. (144)
The study of kinase-substrate relationships is essential to gain a complete understanding of the functions of these enzymes and their downstream targets in both physiological and pathological states. CK2 is an evolutionarily conserved serine/threonin