Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Emily A. Hull-Ryde"'
Autor:
Douglas K. Graham, H. Shelton Earp, Stephen V. Frye, Xiaodong Wang, Gary L. Johnson, William P. Janzen, Emily A. Hull-Ryde, Jacqueline Norris-Drouin, Catherine Simpson, Dmitri Kireev, Chao Yang, Jing Liu, Christopher T. Cummings, Debra M. Hunter, Susan Sather, Alesia Y. Trakhimets, Lance A. Batchelor, J. Kimble Frazer, Jennifer Schlegel, Deborah DeRyckere, Sandra Christoph
PDF - 164KB, Jurkat and 697 cell cultures were treated with UNC569 (500 nM) for 1 hour. Pervanadate was added to cell cultures for 3 minutes to stabilize the phosphorylated form of Mer. Cells were harvested after 24 and after 48 hours. Mer was immuno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0b792aace27e76d7bcaa5f15a741f4e
https://doi.org/10.1158/1535-7163.22498869.v1
https://doi.org/10.1158/1535-7163.22498869.v1
Autor:
Douglas K. Graham, H. Shelton Earp, Stephen V. Frye, Xiaodong Wang, Gary L. Johnson, William P. Janzen, Emily A. Hull-Ryde, Jacqueline Norris-Drouin, Catherine Simpson, Dmitri Kireev, Chao Yang, Jing Liu, Christopher T. Cummings, Debra M. Hunter, Susan Sather, Alesia Y. Trakhimets, Lance A. Batchelor, J. Kimble Frazer, Jennifer Schlegel, Deborah DeRyckere, Sandra Christoph
PDF - 172KB, Jurkat cell cultures were treated with the indicated concentrations of UNC569 for 1 hour. Pervanadate was added to cell cultures for 3 minutes to stabilize the phosphorylated form of Tyro3. Tyro3 was immunoprecipitated from cell lysates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15fd6e6b0eb551d5ec5540b41a540d51
https://doi.org/10.1158/1535-7163.22498872.v1
https://doi.org/10.1158/1535-7163.22498872.v1
Autor:
Douglas K. Graham, H. Shelton Earp, Stephen V. Frye, Xiaodong Wang, Gary L. Johnson, William P. Janzen, Emily A. Hull-Ryde, Jacqueline Norris-Drouin, Catherine Simpson, Dmitri Kireev, Chao Yang, Jing Liu, Christopher T. Cummings, Debra M. Hunter, Susan Sather, Alesia Y. Trakhimets, Lance A. Batchelor, J. Kimble Frazer, Jennifer Schlegel, Deborah DeRyckere, Sandra Christoph
PDF - 294KB, TAM receptor expression in Jurkat cell line was detected by western blot analysis. Whole cell lysates were prepared and phosphorylated (denoted by p-) and total proteins were detected. Western blots representative of three independent ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5aaa550c21b0e6ea25a3b97df14e5550
https://doi.org/10.1158/1535-7163.22498875
https://doi.org/10.1158/1535-7163.22498875
Autor:
Douglas K. Graham, H. Shelton Earp, Stephen V. Frye, Xiaodong Wang, Gary L. Johnson, William P. Janzen, Emily A. Hull-Ryde, Jacqueline Norris-Drouin, Catherine Simpson, Dmitri Kireev, Chao Yang, Jing Liu, Christopher T. Cummings, Debra M. Hunter, Susan Sather, Alesia Y. Trakhimets, Lance A. Batchelor, J. Kimble Frazer, Jennifer Schlegel, Deborah DeRyckere, Sandra Christoph
PDF - 634KB, Eighteen fish (Myc1-Myc18) were treated with UNC569 for 2 weeks. Animals were imaged pre- and post-treatment, with GFP intensities quantified as described in the text. Ten of 18 fish (55.6%; Myc1-Myc8, Myc10, Myc16) showed >50% regressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ff6aa50828c6ca22386951e59806f8d
https://doi.org/10.1158/1535-7163.22498863
https://doi.org/10.1158/1535-7163.22498863
Autor:
Douglas K. Graham, H. Shelton Earp, Stephen V. Frye, Xiaodong Wang, Gary L. Johnson, William P. Janzen, Emily A. Hull-Ryde, Jacqueline Norris-Drouin, Catherine Simpson, Dmitri Kireev, Chao Yang, Jing Liu, Christopher T. Cummings, Debra M. Hunter, Susan Sather, Alesia Y. Trakhimets, Lance A. Batchelor, J. Kimble Frazer, Jennifer Schlegel, Deborah DeRyckere, Sandra Christoph
PDF - 358KB, Cells were plated in methylcellulose in the presence of the indicated concentrations of UNC1653 or vehicle only. Colonies were counted after eight days. Long-term colony growth of Jurkat cells in methylcellulose is shown. Mean values and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d19ae5db09dd2cc4e5bb2320ddf698a
https://doi.org/10.1158/1535-7163.22498866
https://doi.org/10.1158/1535-7163.22498866
Autor:
Carla M.P. Ribeiro, Emily A. Hull-Ryde
Publikováno v:
Current Opinion in Pharmacology. 65:102258
Excessive and chronic airway inflammation associated with increased morbidity and mortality is a hallmark of cystic fibrosis (CF) airway disease. Previous studies underscored the role of endoplasmic reticulum (ER) signaling in CF airway inflammatory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57635f1e75592ed37ef34ed3cf062b6f
https://doi.org/10.1016/j.coph.2022.102258
https://doi.org/10.1016/j.coph.2022.102258
Autor:
Nancy Cheng, Melissa A Porter, Lloyd W Frick, Yvonne Nguyen, Jennifer D Hayden, Ellen F Young, Miriam S Braunstein, Emily A Hull-Ryde, William P Janzen
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96348 (2014)
The tendency for mycobacteria to aggregate poses a challenge for their use in microplate based assays. Good dispersions have been difficult to achieve in high-throughput screening (HTS) assays used in the search for novel antibacterial drugs to treat
Externí odkaz:
https://doaj.org/article/d10bfff817c7471aaf6c76ab85f5218f
Autor:
James M. Coghill, Dmitri Kireev, Mark J. Suto, Emily A. Hull-Ryde, Kenneth H. Pearce, Kenneth A. Fowler, Kelin Li, Melissa A. Porter, Maria F. Sassano, William P. Janzen, Catherine Simpson
Publikováno v:
SLAS Discovery. 23:1083-1091
CC-chemokine receptor 7 (CCR7) is a G protein-coupled receptor expressed on a variety of immune cells. CCR7 plays a critical role in the migration of lymphocytes into secondary lymphoid tissues. CCR7 expression, however, has been linked to numerous d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d31296fc937e4865b5464fc58e236c0
https://doi.org/10.1177/2472555218780917
https://doi.org/10.1177/2472555218780917
Autor:
William J. Zuercher, Scott A. Wildman, James W. Janetka, Emily A. Hull-Ryde, Keliang Tang, Raymond Hui, William P. Janzen, L. David Sibley, Michael A. Stashko, Catherine Simpson, Matthieu Schapira, Dmitri Kireev, Nathaniel G. Jones
Publikováno v:
ACS Infectious Diseases. 2:194-206
The protozoan parasite Toxoplasma gondii secretes a family of serine-threonine protein kinases into its host cell in order to disrupt signaling and alter immune responses. One prominent secretory effector is the rhoptry protein 18 (ROP18), a serine-t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6603c5e3250cc54be9862720fbf409c
https://doi.org/10.1021/acsinfecdis.5b00102
https://doi.org/10.1021/acsinfecdis.5b00102
Autor:
Chao Yang, Gary L. Johnson, Sandra Christoph, Jing Liu, Susan Sather, William P. Janzen, Deborah DeRyckere, Xiaodong Wang, Debra Hunter, Jennifer Schlegel, Catherine Simpson, Jacqueline Norris-Drouin, H. Shelton Earp, Douglas K. Graham, Alesia Y. Trakhimets, Lance Batchelor, Christopher T. Cummings, Stephen V. Frye, Emily A. Hull-Ryde, Dmitri Kireev, J. Kimble Frazer
Publikováno v:
Molecular Cancer Therapeutics. 12:2367-2377
Acute lymphoblastic leukemia (ALL) is the most common malignancy in children. Although survival rates have improved, patients with certain biologic subtypes still have suboptimal outcomes. Current chemotherapeutic regimens are associated with short-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f58befc22ef4d0b8ab4fad7c1cb77ea
https://doi.org/10.1158/1535-7163.mct-13-0040
https://doi.org/10.1158/1535-7163.mct-13-0040