Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Emily A. Hoyt"'
Autor:
Michael J. Deery, Marianne Schimpl, Derek Barratt, Hilary J. Lewis, Morgan Thomas, David Robinson, Deepa Bhavsar, Michael S. Bodnarchuk, Kirsten McAulay, Michael J. Waring, Derek Ogg, Emily A. Hoyt, Richard A. Ward, Gonçalo J. L. Bernardes, Jason Grant Kettle
Publikováno v:
Journal of the American Chemical Society. 142:10358-10372
With a resurgence in interest in covalent drugs, there is a need to identify new moieties capable of cysteine bond formation that are differentiated from commonly employed systems such as acrylamide. Herein, we report on the discovery of new alkynyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::698b7b9835c15e18abf6592ff62a81ee
https://doi.org/10.1021/jacs.9b13391
https://doi.org/10.1021/jacs.9b13391
Autor:
Emily A. Hoyt, Gonzalo Jiménez-Osés, Claudio D. Navo, Ester Jiménez-Moreno, Antonio J. Moreno-Vargas, Alena Istrate, Inmaculada Robina, Enrique Gil de Montes, Gonçalo J. L. Bernardes, Francisco Corzana
Publikováno v:
Angewandte Chemie International Edition. 59:6196-6200
An azanorbornadiene bromovinyl sulfone reagent for cysteine-selective bioconjugation has been developed. Subsequent reaction with dipyridyl tetrazine leads to bond cleavage and formation of a pyrrole-linked conjugate. The latter involves ligation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c633a78c85d18db898c994f7af8102a9
https://doi.org/10.1002/anie.201914529
https://doi.org/10.1002/anie.201914529
Autor:
Enrique Gil de Montes, Alena Istrate, Claudio D. Navo, Ester Jiménez‐Moreno, Emily A. Hoyt, Francisco Corzana, Inmaculada Robina, Gonzalo Jiménez‐Osés, Antonio J. Moreno‐Vargas, Gonçalo J. L. Bernardes
Publikováno v:
Angewandte Chemie. 132:6255-6259
An azanorbornadiene bromovinyl sulfone reagent for cysteine‐selective bioconjugation has been developed. Subsequent reaction with dipyridyl tetrazine leads to bond cleavage and formation of a pyrrole‐linked conjugate. The latter involves ligation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a95329f7e059fc84038e28db2d478b8
https://doi.org/10.1002/ange.201914529
https://doi.org/10.1002/ange.201914529
Publikováno v:
Nature Reviews Chemistry. 3:147-171
Proteins constitute the majority of nature’s worker biomolecules. Designed for specific functions, complex tertiary structures make proteins ideal candidates for analysing natural systems and creating novel biological tools. Owing to both their lar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4abf821ee70d335d4f4ded960655b89b
https://doi.org/10.1038/s41570-019-0079-1
https://doi.org/10.1038/s41570-019-0079-1
Autor:
Emily M. Hoyt, John N. Hooker
Fracture patterns, interactions, and crosscutting relationships are tools for interpretation of fractures as paleostress indicators for past tectonic events and as past or present-day fluid-flow networks. In the Appalachian Basin in Central Pennsylva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89c3073403b82f296050cc71f64304a9
https://doi.org/10.5194/se-2020-50
https://doi.org/10.5194/se-2020-50
Autor:
Emily M. Hoyt, John N. Hooker
Publikováno v:
Marine and Petroleum Geology. 132:105240
Although fractures are commonly assumed to stem from physical, tectonic deformations, fractures may instead form in response to chemical processes. Within the Appalachian Basin in Central Pennsylvania lie multiple sets of fractures hosted within laye
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36f72eed004a1576738d84506453f38b
https://doi.org/10.1016/j.marpetgeo.2021.105240
https://doi.org/10.1016/j.marpetgeo.2021.105240
Publikováno v:
Cell Reports Physical Science. 1:100247
Summary Optimizing reaction conditions depends on expert chemistry knowledge and laborious exploration of reaction parameters. To automate this task and augment chemical intuition, we here report a computational tool to navigate search spaces. Our ap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4e9f91ebffb80f6005b737a3e50a79a
https://doi.org/10.1016/j.xcrp.2020.100247
https://doi.org/10.1016/j.xcrp.2020.100247
Publikováno v:
Journal of Anxiety Disorders. 19:557-572
Using Mennin, Heimberg, Turk, and Fresco's [Emotion regulation deficits as a key feature of generalized anxiety disorder: Testing a theoretical model, submitted for publication] conceptualization of generalized anxiety disorder (GAD) as a syndrome in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf74f44a253df6b72018b04fea2c0393
https://doi.org/10.1016/j.janxdis.2004.06.001
https://doi.org/10.1016/j.janxdis.2004.06.001
Autor:
Emily R. Hoyt, Mary Jane Rapport
Publikováno v:
Pediatric physical therapy : the official publication of the Section on Pediatrics of the American Physical Therapy Association. 26(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a4bb91c02355812d0800ff14e6ac9c5
https://pubmed.ncbi.nlm.nih.gov/24356322
https://pubmed.ncbi.nlm.nih.gov/24356322