Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Emily A. Hileman"'
Autor:
Evan R. DeVallance, Heidi M. Schmidt, Madison Seman, Sara E. Lewis, Katherine C. Wood, Schuyler D. Vickers, Scott A. Hahn, Murugesan Velayutham, Emily A. Hileman, Dario A. Vitturi, Roberta Leonardi, Adam C. Straub, Eric E. Kelley
Publikováno v:
Redox Biology, Vol 67, Iss , Pp 102866- (2023)
We recently reported a previously unknown salutary role for xanthine oxidoreductase (XOR) in intravascular heme overload whereby hepatocellular export of XOR to the circulation was identified as a seminal step in affording protection. However, the ce
Externí odkaz:
https://doaj.org/article/87ca64a023a542648045412108a3db24
Autor:
Heidi M. Schmidt, Evan R. DeVallance, Sara E. Lewis, Katherine C. Wood, Gowtham K. Annarapu, Mara Carreño, Scott A. Hahn, Madison Seman, Brooke A. Maxwell, Emily A. Hileman, Julia Z. Xu, Murugesan Velayutham, Werner J. Geldenhuys, Dario A. Vitturi, Sruti Shiva, Eric E. Kelley, Adam C. Straub
Publikováno v:
Redox Biology, Vol 62, Iss , Pp 102636- (2023)
Xanthine oxidase (XO) catalyzes the catabolism of hypoxanthine to xanthine and xanthine to uric acid, generating oxidants as a byproduct. Importantly, XO activity is elevated in numerous hemolytic conditions including sickle cell disease (SCD); howev
Externí odkaz:
https://doaj.org/article/fc1d13f5ed7a4f76bf1f12017427f9c4
Autor:
Sara E. Lewis, Lihua Li, Marco Fazzari, Sonia R. Salvatore, Jiang Li, Emily A. Hileman, Brooke A. Maxwell, Francisco J. Schopfer, Gavin E. Arteel, Nicholas K.H. Khoo, Eric E. Kelley
Publikováno v:
Advances in Redox Research, Vol 6, Iss , Pp 100051- (2022)
Recent reports have clearly demonstrated a tight correlation between obesity and elevated circulating uric acid levels (hyperuricemia). However, nearly all preclinical work in this area has been completed with male mice, leaving the field with a cons
Externí odkaz:
https://doaj.org/article/f44e15175fa74bed8879c6cb61d96b9f