Zobrazeno 1 - 10
of 243
pro vyhledávání: '"Emily A. Adams"'
Autor:
Jae-Yeon Choi, Shalev Gihaz, Muhammad Munshi, Pallavi Singh, Pratap Vydyam, Patrice Hamel, Emily M. Adams, Xinghui Sun, Oleh Khalimonchuk, Kevin Fuller, Choukri Ben Mamoun
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-16 (2024)
Summary Fungal infections, a leading cause of mortality among eukaryotic pathogens, pose a growing global health threat due to the rise of drug-resistant strains. New therapeutic strategies are urgently needed to combat this challenge. The PCA pathwa
Externí odkaz:
https://doaj.org/article/e15b5858c0af4498aceef87bb26f72b5
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
ObjectiveThe fungal unfolded protein response consists of a two-component relay in which the ER-bound sensor, IreA, splices and activates the mRNA of the transcription factor, HacA. Previously, we demonstrated that hacA is essential for Aspergillus f
Externí odkaz:
https://doaj.org/article/e434a21a8f4d42d88c3addac6ff0af0c
Autor:
Rachel L. Byrne, Tom Wingfield, Emily R. Adams, Sayera Banu, John Samson Bimba, Andrew Codlin, Ana Cubas Atienzar, Tushar Garg, Stephen John, Ricardo Queiroz Gurgel, Melissa Sander, Victor Santana Santos, S. Bertel Squire, Luan Nguyen Quang Vo, Jacob Creswell
Publikováno v:
BMC Global and Public Health, Vol 2, Iss 1, Pp 1-9 (2024)
Abstract Current strategies to promptly, effectively, and equitably screen people with tuberculosis (TB) and link them to diagnosis and care are insufficient; new approaches are required to find the millions of people around the world with TB who are
Externí odkaz:
https://doaj.org/article/73010fd8a2ea4627b9519e06f539273f
Autor:
Usa Boonyuen, Beatriz Aira C. Jacob, Jutamas Wongwigkan, Kamonwan Chamchoy, Natsamon Singha-art, Natnicha Pengsuk, Duantida Songdej, Emily R. Adams, Thomas Edwards, Supat Chamnanchanunt, Syazwani Itri Amran, Nurriza Ab Latif, Naveen Eugene Louis, Shamini Chandran
Publikováno v:
Malaria Journal, Vol 23, Iss 1, Pp 1-17 (2024)
Abstract Background It was hypothesized that glucose-6-phosphate dehydrogenase (G6PD) deficiency confers a protective effect against malaria infection, however, safety concerns have been raised regarding haemolytic toxicity caused by radical cure wit
Externí odkaz:
https://doaj.org/article/8d6ac690322f4154b192ebeed6d537c9
Autor:
Thaila Fernanda dos Reis, Patrícia Alves de Castro, Rafael Wesley Bastos, Camila Figueiredo Pinzan, Pedro F. N. Souza, Suzanne Ackloo, Mohammad Anwar Hossain, David Harold Drewry, Sondus Alkhazraji, Ashraf S. Ibrahim, Hyunil Jo, Jorge D. Lightfoot, Emily M. Adams, Kevin K. Fuller, William F. deGrado, Gustavo H. Goldman
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Fungal infections cause more than 1.5 million deaths a year. Due to emerging antifungal drug resistance, novel strategies are urgently needed to combat life-threatening fungal diseases. Here, we identify the host defense peptide mimetic, bri
Externí odkaz:
https://doaj.org/article/95f2a58a934d446abc7358a90c1dec91
Autor:
Alice J. Fraser, Caitlin Greenland-Bews, Daniel Kelly, Christopher T. Williams, LSTM Diagnostics Group, CONDOR Steering Group, Richard Body, Emily R. Adams, Ana Cubas Atienzar, Thomas Edwards, David J. Allen
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract The emergence of severe acute respiratory syndrome 2 (SARS-CoV-2) variants of concern (VOCs), with mutations linked to increased transmissibility, vaccine escape and virulence, has necessitated the widespread genomic surveillance of SARS-CoV
Externí odkaz:
https://doaj.org/article/c1bd2a7b2fb246349be8342813486c5c
Autor:
Manali M Kamath, Jorge D Lightfoot, Emily M Adams, Ryan M Kiser, Becca L Wells, Kevin K Fuller
Publikováno v:
PLoS Pathogens, Vol 19, Iss 10, p e1011435 (2023)
The Aspergillus fumigatus unfolded protein response (UPR) is a two-component relay consisting of the ER-bound IreA protein, which splices and activates the mRNA of the transcription factor HacA. Spliced hacA accumulates under conditions of acute ER s
Externí odkaz:
https://doaj.org/article/dc7d1e005e8b4554a64926543ada932c
Autor:
Xavier C. Ding, Sandra Incardona, Elisa Serra-Casas, Sarah C. Charnaud, Hannah C. Slater, Gonzalo J. Domingo, Emily R. Adams, Feiko O. ter Kuile, Aaron M. Samuels, Simon Kariuki, Sabine Dittrich
Publikováno v:
Malaria Journal, Vol 22, Iss 1, Pp 1-15 (2023)
Abstract Background Rapid diagnostic tests (RDTs) are effective tools to diagnose and inform the treatment of malaria in adults and children. The recent development of a highly sensitive rapid diagnostic test (HS-RDT) for Plasmodium falciparum has pr
Externí odkaz:
https://doaj.org/article/965445e4cc06448c8f25140133b612e6
Autor:
Caitlin Greenland-Bews, Rachel L. Byrne, Sophie I. Owen, Rachel L. Watkins, Daisy Bengey, Kate Buist, Karina Clerkin, Camille Escadafal, Lorna S. Finch, Susan Gould, Emanuele Giorgi, Andy Hodgkinson, Larysa Mashenko, Darren Powell, Helen R. Savage, Caitlin R. Thompson, Lance Turtle, Jahanara Wardale, Dominic Wooding, Thomas Edwards, Ana Cubas Atienzar, Emily R. Adams
Publikováno v:
BMC Infectious Diseases, Vol 23, Iss 1, Pp 1-7 (2023)
Abstract Background Rapid determination of an individual’s antibody status can be beneficial in understanding an individual’s immune response to SARS-CoV-2 and for initiation of therapies that are only deemed effective in sero-negative individual
Externí odkaz:
https://doaj.org/article/98c74c74a31a4488879b6a6d9ad46289
Autor:
Thomas Edwards, Christopher T. Williams, Macrine Olwala, Pauline Andang’o, Walter Otieno, Grace N. Nalwa, Abimbola Akindolire, Ana I. Cubas-Atienzar, Toby Ross, Olukemi O. Tongo, Emily R. Adams, Helen Nabwera, Stephen Allen
Publikováno v:
Antimicrobial Resistance and Infection Control, Vol 12, Iss 1, Pp 1-8 (2023)
Abstract Objectives Neonatal sepsis, a major cause of death amongst infants in sub-Saharan Africa, is often gut derived. Gut colonisation by Enterobacteriaceae producing extended spectrum beta-lactamase (ESBL) or carbapenemase enzymes can lead to ant
Externí odkaz:
https://doaj.org/article/7bd8064a20944f1f9fe511f56ad506a9