Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Emily A. Reiff"'
Publikováno v:
Anesthesiology Research and Practice, Vol 2020 (2020)
Background. The most common complication after cesarean delivery is surgical site infection. Antibiotic prophylaxis reduces infectious morbidity and current anesthetic quality metrics include preincision antibiotic prophylaxis. Recently, studies sugg
Externí odkaz:
https://doaj.org/article/fec5a8a08ae94e28af7ac310f8219319
Autor:
Rossano Lucius T, Michael A. Schmidt, Vu Chi Truc, Jacob Albrecht, Andrew G. Lee, Xinhua Qian, Ehrlic Lo, Steven L. Goldberg, Emily A. Reiff, Jaan A. Pesti, Chao Hang, Kenneth J. Natalie, Animesh Goswami, Zhiwei Guo, Chenchi Wang
Publikováno v:
Organic Process Research & Development. 19:1317-1322
The process development and large scale synthesis for the β-hydroxyamino amide 1 is described. The route evolved from a multistep sequence utilizing a classical resolution to a two-step enantioselective process involving an enzyme-catalyzed aldol re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e78e620e78b1f8852562c1c09f2eda3c
https://doi.org/10.1021/acs.oprd.5b00192
https://doi.org/10.1021/acs.oprd.5b00192
Autor:
Sarah C, Lassey, Emily S, Reiff, Lori, Dobson, Bryann, Bromley, Louise, Wilkins-Haug, Deborah, Bartz, Sarah E, Little
Publikováno v:
Prenatal diagnosis. 37(7)
The objective of this study is to compare the gestational age at termination for trisomy 13, 18, or 21 (aneuploidy) before and after the introduction of noninvasive prenatal testing (NIPT).A retrospective cohort of women undergoing termination for an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7511f234c1ae1ddbf32c52316b11a4d7
https://pubmed.ncbi.nlm.nih.gov/28419568
https://pubmed.ncbi.nlm.nih.gov/28419568
Autor:
Emily A. Reiff, Michael E. Kopach
Publikováno v:
Future Medicinal Chemistry. 4:1395-1398
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a794913af2d18cd79eceb09950b8d16e
https://doi.org/10.4155/fmc.12.78
https://doi.org/10.4155/fmc.12.78
Publikováno v:
Organic Process Research & Development. 16:567-576
This work presents a process modeling-based methodology towards quality by design that was applied throughout the development lifecycle of the ibipinabant API step. By combining mechanistic kinetic modeling with fundamental thermodynamics, the degrad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::821147381a1236f618dcb8ef368b121a
https://doi.org/10.1021/op2003024
https://doi.org/10.1021/op2003024
Autor:
Sunil A. David, Gunda I. Georg, David Vander Velde, John T. Henri, Richard H. Himes, Sajiv K. Nair, Ting Lan Chiu, Bollu S. Reddy, Ramappa Chakrasali, Elizabeth A. Amin, Emily A. Reiff, Jack F. Greiner
Publikováno v:
The Journal of Organic Chemistry. 75:86-94
Three photoaffinity labeled derivatives of epothilone D were prepared by total synthesis, using efficient novel asymmetric synthesis methods for the preparation of two important synthetic building blocks. The key step for the asymmetric synthesis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb6fba875342da743f14b5984997024e
https://doi.org/10.1021/jo901752v
https://doi.org/10.1021/jo901752v
Autor:
Hanumaiah Telikepalli, Douglas R. Powell, Mary L. Michaelis, Emily A. Reiff, Gunda I. Georg, Sabah Ansar, Kelly E. Desino, Kenneth L. Audus, Richard H. Himes
Publikováno v:
Journal of Medicinal Chemistry. 52:7537-7543
Compounds that interact with microtubules, such as paclitaxel, have been shown to possess protective properties against beta-amyloid (Abeta) induced neurodegeneration associated with Alzheimer's disease. In this work, the novel agent (3R,5S,7as)-(3,5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83051294ea27e224e8e753fb11f21790
https://doi.org/10.1021/jm900254k
https://doi.org/10.1021/jm900254k
Autor:
Derek Berglund, Jeffrey T. Bien, John Wasylak, Purushotham Vemishetti, David J. Kacsur, Jun Qiu, Oscar W. Haas, Chien-Kuang Chen, Yeung Y. Chan, Carrie A. Costello, Lori Spangler, Emily A. Reiff, Jale Muslehiddinoglu, Dale Vanyo, Stephane Gingras, Jaan A. Pesti, Nina Nguyen, Albert J. DelMonte, John A. Grosso, Chiajen Lai, Simon Leung, Wendel W. Doubleday, Michael J. Totleben, Paul Demena, Elisabeth Corbett, Martina Olzog, Dominique Thoraval, Serge Benoit, Melanie Miller, Robert P. Discordia, Zhinong Gao, Paul R. Brodfuehrer, Chenkou Wei
Publikováno v:
Organic Process Research & Development. 13:716-728
The development of a safe, robust process for the preparation of ravuconazole (1), an antifungal agent, is described. The discovery and development of procedures enabling the efficient synthesis of multikilogram quantities of 1 and the process demons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::efd3df18d5b9bf645964394a96c66206
https://doi.org/10.1021/op900065c
https://doi.org/10.1021/op900065c
Autor:
David VanderVelde, Sajiv K. Nair, Gunda I. Georg, Richard H. Himes, Emily A. Reiff, Oliver E. Hutt, Jack F. Greiner, Bollu S. Reddy, Jun Inagaki, Elizabeth A. Amin, Ting Lan Chiu, John T. Henri
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 19:3293-3296
The total synthesis of 22-(3-azidobenzoyloxy)methyl epothilone C is described as a potential photoaffinity probe to elucidate the beta-tubulin binding site. A sequential Suzuki-aldol-Yamaguchi macrolactonization strategy was utilized employing a nove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::674c6652d0607744da6be034a4c91fc2
https://doi.org/10.1016/j.bmcl.2009.04.077
https://doi.org/10.1016/j.bmcl.2009.04.077
Publikováno v:
Prenatal diagnosis. 36(3)
This study aimed to examine the role of the 11- to 14-week ultrasound in women with negative cell-free DNA screening.A retrospective cohort study of women at increased risk for aneuploidy based on age or medical history and negative cell-free DNA scr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::925ce3d82d3f69090f533fdecd1985a3
https://pubmed.ncbi.nlm.nih.gov/26748490
https://pubmed.ncbi.nlm.nih.gov/26748490