Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Emily, Liffick"'
Autor:
Edward M. Sellers, Li Shen Loo, Erin G Doty, Darren Wilbraham, Paul Berg, Max Tsai, Emily Liffick
Publikováno v:
Journal of Clinical Pharmacology
Lasmiditan is a centrally penetrant, highly selective 5‐hydroxytryptamine (serotonin) receptor 1F (5HT1F) agonist under development as a novel therapy for acute treatment of migraine. A phase 1 randomized, placebo‐ and positive‐controlled cross
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8760e4485c07f9efd1185d9fa84470ea
http://europepmc.org/articles/PMC7078915
http://europepmc.org/articles/PMC7078915
Autor:
Jianing Wang, Erin G Doty, Paul Rizzoli, Emily Liffick, Andrew S. Buchanan, Sherie A. Dowsett, John H. Krege
Publikováno v:
Cephalalgia
Background We assessed the safety profile of lasmiditan, a selective 5-HT1F receptor agonist without vasoconstrictive activity being developed as an acute therapy for migraine. Methods SAMURAI and SPARTAN were Phase 3 double-blind studies of patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::041c05b65ad498c42dab60e10a19cb6f
https://doi.org/10.1177/0333102419855080
https://doi.org/10.1177/0333102419855080
Autor:
Michael M, Francis, Tom A, Hummer, Emily, Liffick, Jenifer L, Vohs, Nikki F, Mehdiyoun, Andrew C, Visco, Ziyi, Yang, Richard J, Kovacs, Ying, Zhang, Alan, Breier
Publikováno v:
Brain imaging and behavior. 15(4)
Several lines of evidence have implicated white matter (WM) deficits in schizophrenia, including microstructural alterations from diffusion tensor (DTI) brain imaging studies. It has been proposed that dysregulated inflammatory processes, including h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3e58592840fa8cdc9f6da48203102ea0
https://pubmed.ncbi.nlm.nih.gov/32893328
https://pubmed.ncbi.nlm.nih.gov/32893328
Autor:
Andrew Visco, Jenifer L. Vohs, Alan Breier, Michael M. Francis, Teresa C. Kulig, Emily Liffick, Miji Um, Matthew G. Yung, Ying Zhang, Tom A. Hummer, Nikki Mehdiyoun, Ziyi Yang, Mehrdad Motamed
Publikováno v:
Brain Imaging and Behavior. 13:852-861
Cognitive dysfunction is a core facet of schizophrenia that is present early in the course of the illness and contributes to diminished functioning and outcomes. Repetitive transcranial magnetic stimulation (rTMS) is a relatively new neuropsychiatric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8779e78c655d3bdb9ad1a91126146b82
https://doi.org/10.1007/s11682-018-9902-4
https://doi.org/10.1007/s11682-018-9902-4
Autor:
Jennifer Vohs, Brenna C. McDonald, Tom A. Hummer, Nicole F. Mehdiyoun, Emily Liffick, Ziyi Yang, Alan Breier, Michael M. Francis, Andrew J. Saykin
Publikováno v:
Schizophrenia Bulletin
Background Estrogen therapies, such as estradiol, have shown promise as therapeutics for schizophrenia; however, safety and tolerability concerns, including feminization effects in men and cancer and stroke risk in pre-menopausal women, may limit the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f58cb47f8e0289d59aa3626513d3b7a
https://doi.org/10.1093/schbul/sbaa031.098
https://doi.org/10.1093/schbul/sbaa031.098
Autor:
Scott W. Andersen, Douglas E. James, Yingying Guo, Emily Liffick, Scott A. Monk, Mosun Ayan-Oshodi, Kathleen M. Hillgren, Brian A. Willis
Publikováno v:
Journal of clinical pharmacologyReferences. 60(1)
Lanabecestat is a human β-site amyloid precursor protein-cleaving enzyme 1 inhibitor in development to slow disease progression in patients with early Alzheimer's disease. The study evaluated the breast cancer resistance protein (BCRP) inhibition po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb7eb57f41e5df325c7924106bb0471e
https://pubmed.ncbi.nlm.nih.gov/31378968
https://pubmed.ncbi.nlm.nih.gov/31378968
Autor:
Alan Breier, Emily Liffick, Tom A. Hummer, Nicole Mehdyoun, Jennifer Vohs, Michael M. Francis
BACKGROUND: New medications with novel targets are needed for schizophrenia. Several lines of evidence indicate that inflammatory processes including aberrant lymphocytic activity may be related to the pathophysiology of this illness. These data sugg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::335ec02b262a1a9f239ff4b136fccdbb
https://europepmc.org/articles/PMC6455517/
https://europepmc.org/articles/PMC6455517/
Autor:
Kathleen M. Hillgren, Brian A. Willis, Emily Liffick, Scott A. Monk, Douglas E. James, Mosun Ayan-Oshodi, Yingying Guo, Scott W. Andersen
Publikováno v:
Alzheimer's & Dementia. 14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65fd0b3eb502bd72b2104d89eb2f2afa
https://doi.org/10.1016/j.jalz.2018.06.040
https://doi.org/10.1016/j.jalz.2018.06.040
Autor:
Alan Breier, Brenna C. McDonald, Jenifer L. Vohs, Alexander J. Radnovich, Emily Liffick, Andrew J. Saykin, Nicole F. Mehdiyoun, Tom A. Hummer, Michael M. Francis, Matthew G. Yung
Publikováno v:
Brain Imaging and Behavior. 10:1-11
Studies have demonstrated that episodic memory (EM) is often preferentially disrupted in schizophrenia. The neural substrates that mediate EM impairment in this illness are not fully understood. Several functional magnetic resonance imaging (fMRI) st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e8d1e14e82e4e5a3a57644be17b15ca
https://doi.org/10.1007/s11682-015-9357-9
https://doi.org/10.1007/s11682-015-9357-9
Metacognition, social cognition, and symptoms in patients with first episode and prolonged psychoses
Autor:
Kelly D. Buck, Jay A. Hamm, Bethany L. Leonhardt, Emily Liffick, Jennifer Vohs, Jared Outcalt, Alan Breier, Michael M. Francis, Giancarlo Dimaggio, Kyle Olesek, Paul H. Lysaker, Nikki Mehdiyoun
Publikováno v:
Schizophrenia Research. 153:54-59
While it has been documented that persons with prolonged schizophrenia have deficits in metacognition and social cognition, it is less clear whether these difficulties are already present during a first episode. To explore this issue we assessed and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fc2d08bd6030e8e1552263d03bbadfa
https://doi.org/10.1016/j.schres.2014.01.012
https://doi.org/10.1016/j.schres.2014.01.012