Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Emily, Liffick"'
Autor:
Edward M. Sellers, Li Shen Loo, Erin G Doty, Darren Wilbraham, Paul Berg, Max Tsai, Emily Liffick
Publikováno v:
Journal of Clinical Pharmacology
Lasmiditan is a centrally penetrant, highly selective 5‐hydroxytryptamine (serotonin) receptor 1F (5HT1F) agonist under development as a novel therapy for acute treatment of migraine. A phase 1 randomized, placebo‐ and positive‐controlled cross
Autor:
Jianing Wang, Erin G Doty, Paul Rizzoli, Emily Liffick, Andrew S. Buchanan, Sherie A. Dowsett, John H. Krege
Publikováno v:
Cephalalgia
Background We assessed the safety profile of lasmiditan, a selective 5-HT1F receptor agonist without vasoconstrictive activity being developed as an acute therapy for migraine. Methods SAMURAI and SPARTAN were Phase 3 double-blind studies of patients
Autor:
Michael M, Francis, Tom A, Hummer, Emily, Liffick, Jenifer L, Vohs, Nikki F, Mehdiyoun, Andrew C, Visco, Ziyi, Yang, Richard J, Kovacs, Ying, Zhang, Alan, Breier
Publikováno v:
Brain imaging and behavior. 15(4)
Several lines of evidence have implicated white matter (WM) deficits in schizophrenia, including microstructural alterations from diffusion tensor (DTI) brain imaging studies. It has been proposed that dysregulated inflammatory processes, including h
Autor:
Andrew Visco, Jenifer L. Vohs, Alan Breier, Michael M. Francis, Teresa C. Kulig, Emily Liffick, Miji Um, Matthew G. Yung, Ying Zhang, Tom A. Hummer, Nikki Mehdiyoun, Ziyi Yang, Mehrdad Motamed
Publikováno v:
Brain Imaging and Behavior. 13:852-861
Cognitive dysfunction is a core facet of schizophrenia that is present early in the course of the illness and contributes to diminished functioning and outcomes. Repetitive transcranial magnetic stimulation (rTMS) is a relatively new neuropsychiatric
Autor:
Jennifer Vohs, Brenna C. McDonald, Tom A. Hummer, Nicole F. Mehdiyoun, Emily Liffick, Ziyi Yang, Alan Breier, Michael M. Francis, Andrew J. Saykin
Publikováno v:
Schizophrenia Bulletin
Background Estrogen therapies, such as estradiol, have shown promise as therapeutics for schizophrenia; however, safety and tolerability concerns, including feminization effects in men and cancer and stroke risk in pre-menopausal women, may limit the
Autor:
Scott W. Andersen, Douglas E. James, Yingying Guo, Emily Liffick, Scott A. Monk, Mosun Ayan-Oshodi, Kathleen M. Hillgren, Brian A. Willis
Publikováno v:
Journal of clinical pharmacologyReferences. 60(1)
Lanabecestat is a human β-site amyloid precursor protein-cleaving enzyme 1 inhibitor in development to slow disease progression in patients with early Alzheimer's disease. The study evaluated the breast cancer resistance protein (BCRP) inhibition po
Autor:
Alan Breier, Emily Liffick, Tom A. Hummer, Nicole Mehdyoun, Jennifer Vohs, Michael M. Francis
BACKGROUND: New medications with novel targets are needed for schizophrenia. Several lines of evidence indicate that inflammatory processes including aberrant lymphocytic activity may be related to the pathophysiology of this illness. These data sugg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::335ec02b262a1a9f239ff4b136fccdbb
https://europepmc.org/articles/PMC6455517/
https://europepmc.org/articles/PMC6455517/
Autor:
Kathleen M. Hillgren, Brian A. Willis, Emily Liffick, Scott A. Monk, Douglas E. James, Mosun Ayan-Oshodi, Yingying Guo, Scott W. Andersen
Publikováno v:
Alzheimer's & Dementia. 14
Autor:
Alan Breier, Brenna C. McDonald, Jenifer L. Vohs, Alexander J. Radnovich, Emily Liffick, Andrew J. Saykin, Nicole F. Mehdiyoun, Tom A. Hummer, Michael M. Francis, Matthew G. Yung
Publikováno v:
Brain Imaging and Behavior. 10:1-11
Studies have demonstrated that episodic memory (EM) is often preferentially disrupted in schizophrenia. The neural substrates that mediate EM impairment in this illness are not fully understood. Several functional magnetic resonance imaging (fMRI) st
Metacognition, social cognition, and symptoms in patients with first episode and prolonged psychoses
Autor:
Kelly D. Buck, Jay A. Hamm, Bethany L. Leonhardt, Emily Liffick, Jennifer Vohs, Jared Outcalt, Alan Breier, Michael M. Francis, Giancarlo Dimaggio, Kyle Olesek, Paul H. Lysaker, Nikki Mehdiyoun
Publikováno v:
Schizophrenia Research. 153:54-59
While it has been documented that persons with prolonged schizophrenia have deficits in metacognition and social cognition, it is less clear whether these difficulties are already present during a first episode. To explore this issue we assessed and