Zobrazeno 1 - 10 of 22 pro vyhledávání: '"Emily, Herndon"'
1
Akademický článek
IL-12/IL-23p40 Is Highly Expressed in Secondary Lymphoid Organs and the CNS during All Stages of EAE, but Its Deletion Does Not Affect Disease Perpetuation.
Autor: Petra D Cravens, Rehana Z Hussain, William A Miller-Little, Li-Hong Ben, Benjamin M Segal, Emily Herndon, Olaf Stüve
Publikováno v: PLoS ONE, Vol 11, Iss 10, p e0165248 (2016)
Interleukin (IL)-12 and IL-23 are heterodimers that share the p40 subunit, and both cytokines are critical in the differentiation of T helper (Th)1 and Th17 cells, respectively. Th1 and Th17 effector cells have been implicated in the pathogenesis of
Externí odkaz: https://doaj.org/article/bf8dd2078cc148ea9e9bf73ab97c9381
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2
Akademický článek
A Single Amino Acid Substitution Prevents Recognition of a Dominant Human Aquaporin-4 Determinant in the Context of HLA-DRB1*03:01 by a Murine TCR.
Autor: Benjamine Arellano, Rehana Hussain, William A Miller-Little, Emily Herndon, Doris Lambracht-Washington, Todd N Eagar, Robert Lewis, Don Healey, Steven Vernino, Benjamin M Greenberg, Olaf Stüve
Publikováno v: PLoS ONE, Vol 11, Iss 4, p e0152720 (2016)
BACKGROUND:Aquaporin 4 (AQP4) is considered a putative autoantigen in patients with Neuromyelitis optica (NMO), an autoinflammatory disorder of the central nervous system (CNS). HLA haplotype analyses of patients with NMO suggest a positive associati
Externí odkaz: https://doaj.org/article/8ca48e6324794655b2bd64f1a3d16dee
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3
TLR3 agonism re‐establishesCNSimmune competence duringα4‐integrin deficiency
Autor: Nicolas Loof, Olaf Stüve, Darin T. Okuda, Peter T. Tsai, Emily Herndon, Brianne Dentel, Petra D. Cravens, Rehana Z. Hussain, Richard Doelger, Michael K. Racke
Publikováno v: Annals of Clinical and Translational Neurology. 5:1543-1561
Objective Natalizumab blocks α4-integrin-mediated leukocyte migration into the central nervous system (CNS). It diminishes disease activity in multiple sclerosis (MS), but carries a high risk of progressive multifocal encephalopathy (PML), an opport
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0d2553cd1b59cdc9d3efd539b365767d
https://doi.org/10.1002/acn3.664
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4
α4-integrin deficiency in B cells does not affect disease in a T-cell-mediated EAE disease model
Autor: Rehana Z. Hussain, Todd N. Eagar, Richard Doelger, Valerie Granados, William A. Miller-Little, Olaf Stüve, Petra D. Cravens, Darin T. Okuda, Emily Herndon
Publikováno v: Neurology® Neuroimmunology & Neuroinflammation
ObjectiveThe goal of this study was to investigate the role of CD 19+B cells within the brain and spinal cord during CNS autoimmunity in a peptide-induced, primarily T-cell–mediated experimental autoimmune encephalomyelitis (EAE) model of MS. We hy
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83aa286482af82048134aa19b22320fe
https://pubmed.ncbi.nlm.nih.gov/31403056
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5
TLR3 agonism re-establishes CNS immune competence during
Autor: Rehana Z, Hussain, Petra C, Cravens, Richard, Doelger, Brianne, Dentel, Emily, Herndon, Nicolas, Loof, Peter, Tsai, Darin T, Okuda, Michael K, Racke, Olaf, Stüve
Publikováno v: Annals of Clinical and Translational Neurology
Objective Natalizumab blocks α4‐integrin‐mediated leukocyte migration into the central nervous system (CNS). It diminishes disease activity in multiple sclerosis (MS), but carries a high risk of progressive multifocal encephalopathy (PML), an op
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b0bd8fb436bed287094badaaa9a9826b
https://pubmed.ncbi.nlm.nih.gov/30564621
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7
IL-12/IL-23p40 Is Highly Expressed in Secondary Lymphoid Organs and the CNS during All Stages of EAE, but Its Deletion Does Not Affect Disease Perpetuation
Autor: Rehana Z. Hussain, Petra D. Cravens, Li Hong Ben, William A. Miller-Little, Olaf Stüve, Benjamin M. Segal, Emily Herndon
Publikováno v: PLoS ONE, Vol 11, Iss 10, p e0165248 (2016)
PLoS ONE
Background Interleukin (IL)-12 and IL-23 are heterodimers that share the p40 subunit, and both cytokines are critical in the differentiation of T helper (Th)1 and Th17 cells, respectively. Th1 and Th17 effector cells have been implicated in the patho
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcfe6fd17839713cdafefcb78d925e68
http://europepmc.org/articles/PMC5079572?pdf=render
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8
Neuroanatomic Profile of Polyglutamine Immunoreactivity in Huntington Disease Brains
Autor: Jack M Raisanen, Christa L. Hladik, Charles L. White, Emily Herndon, Ping Shang, Dennis K. Burns
Publikováno v: Journal of Neuropathology & Experimental Neurology. 68:250-261
A pathologic hallmark of Huntington disease (HD) is the presence of intraneuronal aggregates of polyglutamine-containing huntingtin protein fragments. Monoclonal antibody 1C2 is a commercial antibody to normal human TATA-binding protein that detects
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::325aa074f330e025b7e9c900fa959606
https://doi.org/10.1097/nen.0b013e318198d320
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9
The neonatal CNS is not conducive for encephalitogenic Th1 T cells and B cells during experimental autoimmune encephalomyelitis
Autor: Brenda C. Timmons, Hans-Peter Hartung, Li Hong Ben, Martin S. Weber, Emily Herndon, Cyd Castro-Rojas, Benjamine Arellano, Bernd C. Kieseier, Bernhard Hemmer, Scott S. Zamvil, Petra D. Cravens, Rehana Z. Hussain, Olaf Stüve
Publikováno v: Journal of neuroinflammation, vol 10, iss 1
Journal of Neuroinflammation
Multiple sclerosis (MS) is thought to be a CD4+ T cell mediated autoimmune demyelinating disease of the central nervous system (CNS) that is rarely diagnosed during infancy. Cellular and molecular mechanisms that confer disease resistance in this age
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9356aaf263c907074443eadcc60c6c46
https://escholarship.org/uc/item/40v807xz
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10
A Single Amino Acid Substitution Prevents Recognition of a Dominant Human Aquaporin-4 Determinant in the Context of HLA-DRB1*03:01 by a Murine TCR
Autor: Olaf Stüve, William A. Miller-Little, Don Healey, Emily Herndon, Benjamine Arellano, Benjamin Greenberg, Rehana Z. Hussain, Steven Vernino, Todd N. Eagar, Robert Michael Lewis, Doris Lambracht-Washington
Publikováno v: PloS one, vol 11, iss 4
PLoS ONE
PLoS ONE, Vol 11, Iss 4, p e0152720 (2016)
BACKGROUND:Aquaporin 4 (AQP4) is considered a putative autoantigen in patients with Neuromyelitis optica (NMO), an autoinflammatory disorder of the central nervous system (CNS). HLA haplotype analyses of patients with NMO suggest a positive associati
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a86e716b1024bfbd94c7919eaffb85e
https://doi.org/10.1371/journal.pone.0152720
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