Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Emily, Flashman"'
Autor:
Karen C. Heathcote, Thomas P. Keeley, Matti Myllykoski, Malin Lundekvam, Nina McTiernan, Salma Akter, Norma Masson, Peter J. Ratcliffe, Thomas Arnesen, Emily Flashman
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Oxygen homeostasis is maintained in plants and animals by O2-sensing enzymes initiating adaptive responses to low O2 (hypoxia). Recently, the O2-sensitive enzyme ADO was shown to initiate degradation of target proteins RGS4/5 and IL32 via th
Externí odkaz:
https://doaj.org/article/b131b08f851f4fecb899153290804823
Autor:
Kuo-Feng Hsu, Sarah E. Wilkins, Richard J. Hopkinson, Rok Sekirnik, Emily Flashman, Akane Kawamura, James S.O. McCullagh, Louise J. Walport, Christopher J. Schofield
Publikováno v:
Epigenetics, Vol 16, Iss 1, Pp 14-27 (2021)
Post-translational modifications (PTMs) to the tails of the core histone proteins are critically involved in epigenetic regulation. Hypoxia affects histone modifications by altering the activities of histone-modifying enzymes and the levels of hypoxi
Externí odkaz:
https://doaj.org/article/232fbe08a0724f6ca2a8f27be76d1d05
Autor:
Daniel J. Gibbs, Hannah M. Tedds, Anne-Marie Labandera, Mark Bailey, Mark D. White, Sjon Hartman, Colleen Sprigg, Sophie L. Mogg, Rory Osborne, Charlene Dambire, Tinne Boeckx, Zachary Paling, Laurentius A. C. J. Voesenek, Emily Flashman, Michael J. Holdsworth
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
VRN2 is a Polycomb Repressive Complex 2 subunit, best known as a regulator of vernalization that accumulates during prolonged cold. Here Gibbs et al. show that VRN2 is degraded via the N-end rule pathway, which prevents ectopic accumulation of VRN2 i
Externí odkaz:
https://doaj.org/article/c3f1feb667bd4eb9a82a790311dc14ca
Autor:
Mark D. White, Maria Klecker, Richard J. Hopkinson, Daan A. Weits, Carolin Mueller, Christin Naumann, Rebecca O’Neill, James Wickens, Jiayu Yang, Jonathan C. Brooks-Bartlett, Elspeth F. Garman, Tom N. Grossmann, Nico Dissmeyer, Emily Flashman
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
The N-end rule pathway targets substrate proteins for proteasomal degradation. Here, Whiteet al. show that ArabidopsisPLANT CYSTEINE OXIDASEs show dioxygenase activity producing Cys-sulfinic acid at the N-terminus of target proteins, which then act a
Externí odkaz:
https://doaj.org/article/208c41197c3f40509bc868b20218a21a
Autor:
Gabriele Rizzuto, Dapeng Wang, Jinhui Chen, Tin Hang Hung, Anne Charlott Fitzky, Emily Flashman, John J. MacKay
Climate change poses one of the greatest threats to forest ecosystem integrity. An improved understanding of how trees respond to extreme climatic events is crucial to find new ways of managing forests in the face of global warming. In this work we l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::062286265f0e78c0f2aaf98a037c3cc0
https://doi.org/10.22541/au.168265987.75675153/v1
https://doi.org/10.22541/au.168265987.75675153/v1
Publikováno v:
Oxygen Sensing ISBN: 9781071630792
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62bab0830b12ce32eb137f45e12b7f32
https://doi.org/10.1007/978-1-0716-3080-8_13
https://doi.org/10.1007/978-1-0716-3080-8_13
Autor:
Rok Sekirnik, Kuo-Feng Hsu, Akane Kawamura, James S. O. McCullagh, Richard J. Hopkinson, Emily Flashman, Sarah E. Wilkins, Christopher J. Schofield, Louise J. Walport
Publikováno v:
Epigenetics
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Post-translational modifications (PTMs) to the tails of the core histone proteins are critically involved in epigenetic regulation. Hypoxia affects histone modifications by altering the activities of histone-modifying enzymes and the levels of hypoxi
Autor:
Leah J. Taylor-Kearney, Samuel Madden, Jack Wilson, Elisabete Pires, Philip Holdship, Anthony Tumber, Rosalind E. M. Rickaby, Emily Flashman
Publikováno v:
SSRN Electronic Journal.
Publikováno v:
Science
Hammarlund, E U, Flashman, E, Mohlin, S & Licausi, F 2020, ' Oxygen-sensing mechanisms across eukaryotic kingdoms and their roles in complex multicellularity ', Science (New York, N.Y.), vol. 370, no. 6515, 421 . https://doi.org/10.1126/science.aba3512
Hammarlund, E U, Flashman, E, Mohlin, S & Licausi, F 2020, ' Oxygen-sensing mechanisms across eukaryotic kingdoms and their roles in complex multicellularity ', Science (New York, N.Y.), vol. 370, no. 6515, 421 . https://doi.org/10.1126/science.aba3512
Origins and evolution of hypoxia response In our current oxygen-rich atmosphere, the ability of eukaryotic cells to sense variation in oxygen concentrations is essential for adapting to low-oxygen conditions. However, Earth's atmosphere has not alway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebfa1bcd0d6c13546090384613083abb
https://doi.org/10.1126/science.aba3512
https://doi.org/10.1126/science.aba3512
Publikováno v:
RSC Chemical Biology
Reactive oxygen species (ROS) are produced throughout plant cells as a by-product of electron transfer processes. While highly oxidative and potentially damaging to a range of biomolecules, there exists a suite of ROS-scavenging antioxidant strategie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6892be7285af2430208a7f9c0bb11251
https://ora.ox.ac.uk/objects/uuid:f087e3b8-02df-4ef4-a6be-e0460412ab81
https://ora.ox.ac.uk/objects/uuid:f087e3b8-02df-4ef4-a6be-e0460412ab81