Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Emily, Capone"'
Autor:
Emily Capone, Thordur Tryggvason, Ilaria Cela, Beatrice Dufrusine, Morena Pinti, Francesco Del Pizzo, Helga Sigrun Gunnarsdottir, Tommaso Grottola, Vincenzo De Laurenzi, Stefano Iacobelli, Rossano Lattanzio, Gianluca Sala
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-9 (2023)
Abstract HER-3 (also known as ErbB-3) is a human epidermal growth factor receptor tyrosine kinases family member, and its expression in CRC (colorectal cancer) tissues was previously associated with poor prognosis. In this study, HER-3 expression was
Externí odkaz:
https://doaj.org/article/7b22001e53534a3db62fb0db5a62eded
Autor:
Beatrice Dufrusine, Emily Capone, Sara Ponziani, Rossano Lattanzio, Paola Lanuti, Francesco Giansanti, Vincenzo De Laurenzi, Stefano Iacobelli, Rodolfo Ippoliti, Annunziato Mangiola, Gianluca Trevisi, Gianluca Sala
Publikováno v:
Molecular Oncology, Vol 17, Iss 8, Pp 1460-1473 (2023)
Glioblastoma multiforme (GBM) is a lethal disease characterized by an overall survival of about 1 year, making it one of the most aggressive tumours, with very limited therapeutic possibilities. Specific biomarkers for early diagnosis as well as inno
Externí odkaz:
https://doaj.org/article/b0a45f52b02d4c73b287255b528e7860
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-18 (2021)
Abstract The lectin galactoside-binding soluble 3 binding protein (LGALS3BP) is a secreted, hyperglycosylated protein expressed by the majority of human cells. It was first identified as cancer and metastasis associated protein, while its role in inn
Externí odkaz:
https://doaj.org/article/6fad03a0beea4c97b991c37cc47effb3
Autor:
Lucía Gandullo‐Sánchez, Emily Capone, Alberto Ocaña, Stefano Iacobelli, Gianluca Sala, Atanasio Pandiella
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 5, Pp 1-16 (2020)
Abstract Despite impressive clinical benefit obtained with anti‐HER2‐targeted therapies, in advances stages, especially in the metastatic setting, HER2‐positive tumors remain incurable. Therefore, it is important to develop novel strategies to
Externí odkaz:
https://doaj.org/article/60c8022f129d4e80a557c5a7b13dcc4b
Autor:
Alexia Tsakaneli, Victor Corasolla Carregari, Martina Morini, Alessandra Eva, Giuliana Cangemi, Olesya Chayka, Evgeny Makarov, Sandra Bibbò, Emily Capone, Gianluca Sala, Vincenzo De Laurenzi, Evon Poon, Louis Chesler, Luisa Pieroni, Martin R. Larsen, Giuseppe Palmisano, Arturo Sala
Publikováno v:
Open Biology, Vol 11, Iss 12 (2021)
Amplification of the proto-oncogene MYCN is a key molecular aberration in high-risk neuroblastoma and predictive of poor outcome in this childhood malignancy. We investigated the role of MYCN in regulating the protein cargo of extracellular vesicles
Externí odkaz:
https://doaj.org/article/12d0e9b553254367b95d2b65de857eae
Autor:
Aleksandra Adamska, Alice Domenichini, Emily Capone, Verena Damiani, Begum Gokcen Akkaya, Kenneth J. Linton, Pierluigi Di Sebastiano, Xi Chen, Adam B. Keeton, Veronica Ramirez-Alcantara, Yulia Maxuitenko, Gary A. Piazza, Vincenzo De Laurenzi, Gianluca Sala, Marco Falasca
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-14 (2019)
Abstract Background Pancreatic Ductal Adenocarcinoma (PDAC) is an aggressive and lethal disease, lacking effective therapeutic approaches. Available therapies only marginally prolong patient survival and are frequently coupled with severe adverse eve
Externí odkaz:
https://doaj.org/article/84712f0b99aa425c917bb4104624a84d
Autor:
Aikaterini Emmanouilidi, Chanse A. Fyffe, Riccardo Ferro, Charlotte E. Edling, Emily Capone, Simona Sestito, Simona Rapposelli, Rossano Lattanzio, Stefano Iacobelli, Gianluca Sala, Tania Maffucci, Marco Falasca
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-12 (2019)
Abstract Background The very aggressive nature and low survival rate of pancreatic ductal adenocarcinoma (PDAC) dictates the necessity to find novel efficacious therapies. Recent evidence suggests that phosphoinositide 3-kinase (PI3K) and 3-phosphoin
Externí odkaz:
https://doaj.org/article/7a7c4d16610446cf847b2d32f06af08d
Autor:
null Beatrice Dufrusine, null Emily Capone, null Sara Ponziani, null Rossano Lattanzio, null Paola Lanuti, null Francesco Giansanti, null Vincenzo De Laurenzi, null Stefano Iacobelli, null Rodolfo Ippoliti, null Annunziato Mangiola, null Gianluca Trevisi, null Gianluca Sala
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ac733541a015b9665b477341eb0ca42
https://doi.org/10.1002/1878-0261.13453/v3/response1
https://doi.org/10.1002/1878-0261.13453/v3/response1
Autor:
Emily Capone, Rossano Lattanzio, Fabio Gasparri, Paolo Orsini, Cosmo Rossi, Valentina Iacobelli, Vincenzo De Laurenzi, Pier Giorgio Natali, Barbara Valsasina, Stefano Iacobelli, Gianluca Sala
Publikováno v:
Pharmaceutics, Vol 13, Iss 4, p 483 (2021)
HER-3 is becoming an attractive target for antibody–drug conjugate (ADC)-based therapy. Indeed, this receptor and its ligands are found to be overexpressed in several malignancies, and re-activation of its downstream signaling axis is known to play
Externí odkaz:
https://doaj.org/article/cbdde89232044ed284a03558c3f68140
Autor:
Luisa Pieroni, Giuseppe Palmisano, Gianluca Sala, Martina Morini, Evon Poon, Arturo Sala, Louis Chesler, Alessandra Eva, Alexia Tsakaneli, Vincenzo De Laurenzi, Evgeny M. Makarov, Martin R. Larsen, Giuliana Cangemi, Sandra Bibbò, Emily Capone, Olesya Chayka, Victor Corasolla Carregari
Publikováno v:
Tsakaneli, A, Carregari, V C, Morini, M, Eva, A, Cangemi, G, Chayka, O, Makarov, E, Bibbò, S, Capone, E, Sala, G, De Laurenzi, V, Poon, E, Chesler, L, Pieroni, L, Larsen, M R, Palmisano, G & Sala, A 2021, ' MYC regulates metabolism through vesicular transfer of glycolytic kinases ', Open Biology, vol. 11, no. 12, 210276 . https://doi.org/10.1098/rsob.210276
Open Biology
Open Biology, Vol 11, Iss 12 (2021)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Open Biology
Open Biology, Vol 11, Iss 12 (2021)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Electronic supplementary material is available online at https://doi.org/10.6084/m9.figshare.c.5713034. Copyright © 2021 The Authors. Amplification of the proto-oncogene MYCN is a key molecular aberration in high-risk neuroblastoma and predictive of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa9b97ab242ebbd2923beab216db9653
https://findresearcher.sdu.dk:8443/ws/files/197558028/rsob.210276.pdf
https://findresearcher.sdu.dk:8443/ws/files/197558028/rsob.210276.pdf