Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Emilio Y. Lucero‐Garcia Rojas"'
Autor:
Emilio Y. Lucero‐Garcia Rojas, Arfaxad Reyes‐Alcaraz, Kehe Ruan, Bradley K. McConnell, Richard A. Bond
Publikováno v:
FASEB BioAdvances, Vol 4, Iss 12, Pp 758-774 (2022)
Abstract The β2AR is a prototypical G protein‐coupled receptor (GPCR) known to orchestrate different cellular responses by the stimulation of specific signaling pathways. The best‐established signaling pathways for the β2AR are the canonical Gs
Externí odkaz:
https://doaj.org/article/f1ee986d5c6b434dbf21a6fe72535b42
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
ß-arrestins are multifunctional proteins that modulate heptahelical 7 transmembrane receptors, also known as G protein-coupled receptors (GPCRs), a superfamily of receptors that regulate most physiological processes. ß-arrestin modulation of GPCR f
Externí odkaz:
https://doaj.org/article/a1424f82dcd946f1905ba76ee2e2b3e9
Autor:
Arfaxad Reyes-Alcaraz, Emilio Y. Lucero Garcia-Rojas, Elizabeth A. Merlinsky, Jae Young Seong, Richard A. Bond, Bradley K. McConnell
Publikováno v:
Communications Biology. 5
Internalization of membrane proteins plays a key role in many physiological functions; however, highly sensitive and versatile technologies are lacking to study such processes in real-time living systems. Here we describe an assay based on biolumines
Autor:
Arfaxad, Reyes-Alcaraz, Emilio Y, Lucero Garcia-Rojas, Elizabeth A, Merlinsky, Jae Young, Seong, Richard A, Bond, Bradley K, McConnell
Publikováno v:
Communications biology. 5(1)
Internalization of membrane proteins plays a key role in many physiological functions; however, highly sensitive and versatile technologies are lacking to study such processes in real-time living systems. Here we describe an assay based on biolumines
The superfamily of G protein-coupled receptors (GPCRs) consists of biological microprocessors that can activate multiple signaling pathways. Most GPCRs have an orthosteric pocket where the endogenous ligand(s) typically binds. Conversely, allosteric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce814108d48874c1a816e7587ea1a55e
http://www.intechopen.com/articles/show/title/allosteric-modulators-for-gpcrs-as-a-therapeutic-alternative-with-high-potential-in-drug-discovery
http://www.intechopen.com/articles/show/title/allosteric-modulators-for-gpcrs-as-a-therapeutic-alternative-with-high-potential-in-drug-discovery