Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Emilio Varea"'
Autor:
Patrycja Klimczak, Julia Alcaide, Yaiza Gramuntell, Esther Castillo-Gómez, Emilio Varea, Marta Perez-Rando, Juan Nacher
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract The exposure to aversive experiences during early-life affects brain maturation and induces changes in behavior. Additionally, when these experiences coincide with subtle neurodevelopmental alterations, they may contribute to the emergence o
Externí odkaz:
https://doaj.org/article/6187aae5dd234a07ada77d991a006710
Autor:
Simona Coviello, Yaiza Gramuntell, Patrycja Klimczak, Emilio Varea, José Miguel Blasco-Ibañez, Carlos Crespo, Antonio Gutierrez, Juan Nacher
Publikováno v:
Frontiers in Neuroanatomy, Vol 16 (2022)
This work provides evidence of the presence of immature neurons in the human brain, specifically in the layer II of the cerebral cortex. Using surgical samples from epileptic patients and post-mortem tissue, we have found cells with different levels
Externí odkaz:
https://doaj.org/article/d0ffe25d6cce42d29afc0bc24bd79573
Autor:
Julia Alcaide, Ramón Guirado, Carlos Crespo, José Miguel Blasco-Ibáñez, Emilio Varea, Julio Sanjuan, Juan Nacher
Publikováno v:
International Journal of Bipolar Disorders, Vol 7, Iss 1, Pp 1-9 (2019)
Abstract Background Alterations in the structure and physiology of interneurons in the prefrontal cortex (PFC) are important factors in the etiopathology of different psychiatric disorders. Among the interneuronal subpopulations, parvalbumin (PV) exp
Externí odkaz:
https://doaj.org/article/ab3863a5d41c4b61bdb0fabb6a2693e2
Publikováno v:
Folia Neuropathologica, Vol 55, Iss 2, Pp 154-160 (2017)
Neuroinflammation is one of the hallmarks of Alzheimer’s disease. One of the enzymes involved in neuroinflammation, even in early stages of the disease, is COX-2, an inducible cyclooxygenase responsible for the generation of eicosanoids and for the
Externí odkaz:
https://doaj.org/article/cceba4d2286a45c7b7f32368394332c8
Autor:
Marta Perez-Rando, Esther Castillo-Gómez, Ramon Guirado, José Miguel Blasco-Ibañez, Carlos Crespo, Emilio Varea, Juan Nacher
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 11 (2017)
N-methyl-D-aspartate receptors (NMDARs) are present in both pyramidal neurons and interneurons of the hippocampus. These receptors play an important role in the adult structural plasticity of excitatory neurons, but their impact on the remodeling of
Externí odkaz:
https://doaj.org/article/07ecb68226f84706b8798d332865a1bd
Publikováno v:
Neural Plasticity, Vol 2016 (2016)
Dopamine D2 receptors (D2R) in the medial prefrontal cortex (mPFC) are key players in the etiology and therapeutics of schizophrenia. The overactivation of these receptors contributes to mPFC dysfunction. Chronic treatment with D2R agonists modifies
Externí odkaz:
https://doaj.org/article/c99d51f909ec41c7ac089b68e900bae4
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e29516 (2011)
Decreased expression of dopamine D2 receptors (D2R), dysfunction of inhibitory neurotransmission and impairments in the structure and connectivity of neurons in the medial prefrontal cortex (mPFC) are involved in the pathogenesis of schizophrenia and
Externí odkaz:
https://doaj.org/article/c189c6efb2184468ba8955130bc6b82c
Autor:
Jorge E Castro, Emilio Varea, Cristina Márquez, Maria Isabel Cordero, Guillaume Poirier, Carmen Sandi
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8618 (2010)
The stimulation of adult hippocampal neurogenesis by antidepressants has been associated with multiple molecular pathways, but the potential influence exerted by other brain areas has received much less attention. The basolateral complex of the amygd
Externí odkaz:
https://doaj.org/article/6bb1f7105e954ced8a028fc1257154d5
Publikováno v:
Neurochemical Research. 47:3076-3092
Down syndrome (DS) induces a variable phenotype including intellectual disabilities and early development of Alzheimer’s disease (AD). Moreover, individuals with DS display accelerated aging that affects diverse organs, among them the brain. The Ts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::227905760c793755f1adf93ff393907a
https://doi.org/10.1007/s11064-022-03659-0
https://doi.org/10.1007/s11064-022-03659-0
Autor:
Oier Pastor-Alonso, Irene Durá, Sara Bernardo-Castro, Emilio Varea, Teresa Muro-García, Soraya Martín-Suárez, Juan Manuel Encinas-Pérez, Jose Ramon Pineda
Hippocampal seizures mimicking mesial temporal lobe epilepsy (MTLE) cause a profound disruption of the adult neurogenic niche in mice. Seizures provoke neural stem cells to switch to a reactive phenotype (reactive-neural stem cells, React-NSCs)) char
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c985405bd052a0ea53e8c4c09376355
https://doi.org/10.1101/2022.11.02.514820
https://doi.org/10.1101/2022.11.02.514820
