Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Emilio Sanseviero"'
Autor:
Elizabeth L. Hardaker, Emilio Sanseviero, Ankur Karmokar, Devon Taylor, Marta Milo, Chrysis Michaloglou, Adina Hughes, Mimi Mai, Matthew King, Anisha Solanki, Lukasz Magiera, Ricardo Miragaia, Gozde Kar, Nathan Standifer, Michael Surace, Shaan Gill, Alison Peter, Sara Talbot, Sehmus Tohumeken, Henderson Fryer, Ali Mostafa, Kathy Mulgrew, Carolyn Lam, Scott Hoffmann, Daniel Sutton, Larissa Carnevalli, Fernando J. Calero-Nieto, Gemma N. Jones, Andrew J. Pierce, Zena Wilson, David Campbell, Lynet Nyoni, Carla P. Martins, Tamara Baker, Gilberto Serrano de Almeida, Zainab Ramlaoui, Abdel Bidar, Benjamin Phillips, Joseph Boland, Sonia Iyer, J. Carl Barrett, Arsene-Bienvenu Loembé, Serge Y. Fuchs, Umamaheswar Duvvuri, Pei-Jen Lou, Melonie A. Nance, Carlos Alberto Gomez Roca, Elaine Cadogan, Susan E. Critichlow, Steven Fawell, Mark Cobbold, Emma Dean, Viia Valge-Archer, Alan Lau, Dmitry I. Gabrilovich, Simon T. Barry
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract The Ataxia telangiectasia and Rad3-related (ATR) inhibitor ceralasertib in combination with the PD-L1 antibody durvalumab demonstrated encouraging clinical benefit in melanoma and lung cancer patients who progressed on immunotherapy. Here we
Externí odkaz:
https://doaj.org/article/189773f2417346dcbdf8b6281d57effa
Autor:
Dmitry Gabrilovich, Simon Barry, Mark Cobbold, Sehmus Tohumeken, Kathy Mulgrew, Marta Milo, Emilio Sanseviero, Devon Taylor, Mimi Mai, Ali Mostafa, Serge Fuchs
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/cf813e0a4a104ae4b72e78732ed53681
Autor:
Kevin Alicea-Torres, Emilio Sanseviero, Jun Gui, Jinyun Chen, Filippo Veglia, Qiujin Yu, Laxminarasimha Donthireddy, Andrew Kossenkov, Cindy Lin, Shuyu Fu, Charles Mulligan, Brian Nam, Gregory Masters, Fred Denstman, Joseph Bennett, Neil Hockstein, Agnieszka Rynda-Apple, Yulia Nefedova, Serge Y. Fuchs, Dmitry I. Gabrilovich
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
The role of type I interferon signalling in the control of myeloid derived suppressor cells (MDSC) activity remains controversial. Here the authors show that downregulation of type I interferon receptor is observed in MDSC from cancer patients and tu
Externí odkaz:
https://doaj.org/article/eb47431a860f4ab1b301c7219d4359c8
Autor:
Emilio Sanseviero
Publikováno v:
Journal of Clinical Medicine, Vol 8, Iss 10, p 1667 (2019)
Immunotherapy has revolutionized the treatment of cancer patients. Among immunotherapeutic approaches, antibodies targeting immune checkpoint inhibitors Programmed cell death protein 1 (PD-1) and cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) a
Externí odkaz:
https://doaj.org/article/790d93ef860543b0b6effda89b439df9
Autor:
Dmitry I. Gabrilovich, Yulia Nefedova, Dario C. Altieri, Charles Mulligan, Brian Nam, Zachary T. Schug, Andrew V. Kossenkov, Erica L. Stone, Laura Garcia-Gerique, Kevin Alicea-Torres, Ali Mostafa, Emilio Sanseviero, Eric S. Chen, Michela Perego, Irene Bertolini, Hui Deng, Shuyu Fu
Supplemental Video
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77362bd6999c0191301b2c1aa633e40e
https://doi.org/10.1158/2326-6066.22545903.v1
https://doi.org/10.1158/2326-6066.22545903.v1
Autor:
Dmitry I. Gabrilovich, Yulia Nefedova, Dario C. Altieri, Charles Mulligan, Brian Nam, Zachary T. Schug, Andrew V. Kossenkov, Erica L. Stone, Laura Garcia-Gerique, Kevin Alicea-Torres, Ali Mostafa, Emilio Sanseviero, Eric S. Chen, Michela Perego, Irene Bertolini, Hui Deng, Shuyu Fu
Pathologically activated neutrophils (PMN) with immunosuppressive activity, which are termed myeloid-derived suppressor cells (PMN-MDSC), play a critical role in regulating tumor progression. These cells have been implicated in promoting tumor metast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23557be223d0e5236e8ad77c29b536ad
https://doi.org/10.1158/2326-6066.c.6551049.v1
https://doi.org/10.1158/2326-6066.c.6551049.v1
Autor:
Dmitry I. Gabrilovich, Yulia Nefedova, Dario C. Altieri, Charles Mulligan, Brian Nam, Zachary T. Schug, Andrew V. Kossenkov, Erica L. Stone, Laura Garcia-Gerique, Kevin Alicea-Torres, Ali Mostafa, Emilio Sanseviero, Eric S. Chen, Michela Perego, Irene Bertolini, Hui Deng, Shuyu Fu
Supplemental Figures, legends and tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b7b018a6fa2d7e9226af790991b9a37
https://doi.org/10.1158/2326-6066.22545906.v1
https://doi.org/10.1158/2326-6066.22545906.v1
Autor:
Erica L. Stone, Qin Liu, Tara C. Mitchell, Lynn M. Schuchter, Mark P. Rubinstein, Jeff Hammerbacher, Mary Jo Turk, Brian Nam, Ravi K. Amaravadi, Giorgos C. Karakousis, Xiaowei Xu, Xiangfan Yin, Cathy Zheng, Wei Xu, Bulent Arman Aksoy, Tamer B. Shabaneh, Jenna R. Karras, Erin M. O’Brien, Emilio Sanseviero
Supplementary Figure 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5748cb60e9e7c0ed600dceb8778ece8c
https://doi.org/10.1158/2326-6066.22539752
https://doi.org/10.1158/2326-6066.22539752
Autor:
Erica L. Stone, Qin Liu, Tara C. Mitchell, Lynn M. Schuchter, Mark P. Rubinstein, Jeff Hammerbacher, Mary Jo Turk, Brian Nam, Ravi K. Amaravadi, Giorgos C. Karakousis, Xiaowei Xu, Xiangfan Yin, Cathy Zheng, Wei Xu, Bulent Arman Aksoy, Tamer B. Shabaneh, Jenna R. Karras, Erin M. O’Brien, Emilio Sanseviero
Supplementary Figure Legends for S1-4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::625911bc84818c026b86351efd53ba96
https://doi.org/10.1158/2326-6066.22539743.v1
https://doi.org/10.1158/2326-6066.22539743.v1
Autor:
Erica L. Stone, Qin Liu, Tara C. Mitchell, Lynn M. Schuchter, Mark P. Rubinstein, Jeff Hammerbacher, Mary Jo Turk, Brian Nam, Ravi K. Amaravadi, Giorgos C. Karakousis, Xiaowei Xu, Xiangfan Yin, Cathy Zheng, Wei Xu, Bulent Arman Aksoy, Tamer B. Shabaneh, Jenna R. Karras, Erin M. O’Brien, Emilio Sanseviero
Supplementary Figure 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::614ede95e77a92970fddcabd0e7b8783
https://doi.org/10.1158/2326-6066.22539746.v1
https://doi.org/10.1158/2326-6066.22539746.v1