Zobrazeno 1 - 10
of 132
pro vyhledávání: '"Emilio L. Malchiodi"'
Autor:
Mariana G. Selener, Jimena Borgo, Maria Belen Sarratea, Maria Alicia Delfino, Laura C. Laurella, Natacha Cerny, Jessica Gomez, Mauro Coll, Emilio L. Malchiodi, Augusto E. Bivona, Patricia Barrera, Flavia C. Redko, César A. N. Catalán, Andrés Sánchez Alberti, Valeria P. Sülsen
Publikováno v:
Pharmaceutics, Vol 16, Iss 3, p 415 (2024)
Chagas disease, caused by the protozoan Trypanosoma cruzi, affects 6–7 million people worldwide. The dichloromethane extract obtained from the aerial parts of Gymnocoronis spilanthoides var subcordata showed trypanocidal activity in vitro. The frac
Externí odkaz:
https://doaj.org/article/571c6ed2ed6b4a79aeb57bec1d7e4369
Autor:
Andrés Sánchez Alberti, María F. Beer, Natacha Cerny, Augusto E. Bivona, Lucas Fabian, Celina Morales, Albertina Moglioni, Emilio L. Malchiodi, Osvaldo J. Donadel, Valeria P. Sülsen
Publikováno v:
ACS Omega, Vol 7, Iss 1, Pp 968-978 (2021)
Externí odkaz:
https://doaj.org/article/93a99b2c68df431680c071fd6480d767
Autor:
Jimena Borgo, Orlando G. Elso, Jessica Gomez, Mauro Coll, Cesar A. N. Catalán, Juan Mucci, Guzmán Alvarez, Lía M. Randall, Patricia Barrera, Emilio L. Malchiodi, Augusto E. Bivona, María Florencia Martini, Valeria P. Sülsen
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 647 (2023)
Stevia species (Asteraceae) have been a rich source of terpenoid compounds, mainly sesquiterpene lactones, several of which show antiprotozoal activity. In the search for new trypanocidal compounds, S. satureiifolia var. satureiifolia and S. alpina w
Externí odkaz:
https://doaj.org/article/7f501a003c8248bcb73415679501227a
Autor:
Julia Lara, Lautaro Diacovich, Felipe Trajtenberg, Nicole Larrieux, Emilio L. Malchiodi, Marisa M. Fernández, Gabriela Gago, Hugo Gramajo, Alejandro Buschiazzo
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
FasR is a TetR-like transcriptional activator that plays a central role in sensing mycobacterial long-chain fatty acids and regulating lipid biosynthesis in Mycobacterium tuberculosis. Here authors present crystal structures of M. tuberculosis FasR i
Externí odkaz:
https://doaj.org/article/bb60974c393341d483c45f151748dd51
Autor:
María F. Beer, Guillermo F. Reta, Adrián Puerta, Augusto E. Bivona, Andrés Sánchez Alberti, Natacha Cerny, Emilio L. Malchiodi, Carlos E. Tonn, José M. Padrón, Valeria P. Sülsen, Osvaldo J. Donadel
Publikováno v:
Molecules, Vol 27, Iss 10, p 3067 (2022)
Cancer is one of the most important causes of death worldwide. Solid tumors represent the vast majority of cancers (>90%), and the chemotherapeutic agents used for their treatment are still characterized by variable efficacy and toxicity. Sesquiterpe
Externí odkaz:
https://doaj.org/article/ad5495e9721d4061aeb76d6b1912106b
Autor:
Andrés Sanchez Alberti, Augusto E. Bivona, Marina N. Matos, Natacha Cerny, Kai Schulze, Sebastian Weißmann, Thomas Ebensen, Germán González, Celina Morales, Alejandro C. Cardoso, Silvia I. Cazorla, Carlos A. Guzmán, Emilio L. Malchiodi
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
There are several unmet needs in modern immunology. Among them, vaccines against parasitic diseases and chronic infections lead. Trypanosoma cruzi, the causative agent of Chagas disease, is an excellent example of a silent parasitic invasion that aff
Externí odkaz:
https://doaj.org/article/aa1c1391ec164399ad442f6f225b17b7
Autor:
Sofia Noli Truant, Mauricio C. De Marzi, María B. Sarratea, María B. Antonoglou, Ana P. Meo, Laura V. Iannantuono López, María J. Fernández Lynch, Marcos Todone, Emilio L. Malchiodi, Marisa M. Fernández
Publikováno v:
Frontiers in Immunology, Vol 10 (2020)
Bacterial superantigens (SAgs) are enterotoxins that bind to MHC-II and TCR molecules, activating as much as 20% of the T cell population and promoting a cytokine storm which enhances susceptibility to endotoxic shock, causing immunosuppression, and
Externí odkaz:
https://doaj.org/article/6ca271635383458bba0c0f37df1bb984
Autor:
Andrés Sanchez Alberti, Augusto E. Bivona, Natacha Cerny, Kai Schulze, Sebastian Weißmann, Thomas Ebensen, Celina Morales, Angel M. Padilla, Silvia I. Cazorla, Rick L. Tarleton, Carlos A. Guzmán, Emilio L. Malchiodi
Publikováno v:
npj Vaccines, Vol 2, Iss 1, Pp 1-12 (2017)
Chagas disease: protecting from chronic parasitic disease An amalgamation of parasitic proteins may be the first effective vaccine against the as yet untreatable chronic phase of Chagas disease. The infliction, caused by the parasite Trypanosoma cruz
Externí odkaz:
https://doaj.org/article/ae1f0273188b48babe69f8e20ee1e766
Autor:
Orlando G. Elso, Augusto E. Bivona, Andrés Sanchez Alberti, Natacha Cerny, Lucas Fabian, Celina Morales, César A. N. Catalán, Emilio L. Malchiodi, Silvia I. Cazorla, Valeria P. Sülsen
Publikováno v:
Molecules, Vol 25, Iss 9, p 2014 (2020)
The sesquiterpene lactones eupatoriopicrin, estafietin, eupahakonenin B and minimolide have been isolated from Argentinean Astearaceae species and have been found to be active against Trypanosoma cruzi epimastigotes. The aim of this work was to evalu
Externí odkaz:
https://doaj.org/article/65fe52f1e4944dd3a1bbd3ddf385caf1
Autor:
María F. Beer, Augusto E. Bivona, Andrés Sánchez Alberti, Natacha Cerny, Guillermo F. Reta, Víctor S. Martín, José M. Padrón, Emilio L. Malchiodi, Valeria P. Sülsen, Osvaldo J. Donadel
Publikováno v:
Molecules, Vol 24, Iss 6, p 1113 (2019)
Cancer is one of the most important causes of death worldwide. Solid tumors represent the great majority of cancers (>90%) and the chemotherapeutic agents used for their treatment are still characterized by variable efficacy and toxicity. Sesquiterpe
Externí odkaz:
https://doaj.org/article/939a3a209579448d8fbbc0b84cbbd42a