Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Emilio J Laserna-Mendieta"'
Proton-Pump Inhibitors in Eosinophilic Esophagitis: A Review Focused on the Role of Pharmacogenetics
Autor:
Leticia Rodríguez-Alcolado, Pilar Navarro, Laura Arias-González, Elena Grueso-Navarro, Alfredo J. Lucendo, Emilio J. Laserna-Mendieta
Publikováno v:
Pharmaceutics, Vol 16, Iss 4, p 487 (2024)
Proton-pump inhibitors (PPIs) are the most administered first-line treatment for eosinophilic esophagitis (EoE). However, only around half of EoE patients respond histologically to a double dosage of PPI. In addition, 70% of responders maintain EoE i
Externí odkaz:
https://doaj.org/article/1850c715760142a0b73eab56c9f487dc
Autor:
Paula Soria-Chacartegui, Marcos Navares-Gómez, Francisca Molina-Jiménez, Emilio J. Laserna-Mendieta, Laura Arias-González, Pedro Majano, Sergio Casabona, Alfredo J. Lucendo, Francisco Abad-Santos, Cecilio Santander, Pablo Zubiaur
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 7, p 3685 (2024)
Proton pump inhibitors (PPIs) are the first-line drug for eosinophilic esophagitis (EoE), although it is estimated that there is a lack of histological remission in 50% of patients. This research aimed to identify pharmacogenetic biomarkers predictiv
Externí odkaz:
https://doaj.org/article/2935dca5eebe426d97994ce8957bb435
Autor:
Laura Arias-González, Leticia Rodríguez-Alcolado, Emilio J. Laserna-Mendieta, Pilar Navarro, Alfredo J. Lucendo, Elena Grueso-Navarro
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 2, p 927 (2024)
Eosinophilic esophagitis (EoE) is a chronic, progressive, type 2 inflammatory disease with increasing global prevalence. An eosinophil-predominant inflammation that permeates the epithelium and deeper esophageal layers characterizes the disease. Seve
Externí odkaz:
https://doaj.org/article/0c73ada576224495b9d2a2d8505e11cf
Autor:
Nicole R. Narayan, Thomas Weinmaier, Emilio J. Laserna-Mendieta, Marcus J. Claesson, Fergus Shanahan, Karim Dabbagh, Shoko Iwai, Todd Z. DeSantis
Publikováno v:
BMC Genomics, Vol 21, Iss 1, Pp 1-12 (2020)
Abstract Background Shotgun metagenomic sequencing reveals the potential in microbial communities. However, lower-cost 16S ribosomal RNA (rRNA) gene sequencing provides taxonomic, not functional, observations. To remedy this, we previously introduced
Externí odkaz:
https://doaj.org/article/2e6b4f969df745a19bcc593256e0fb44
Autor:
Alfredo J. Lucendo, Cecilio Santander, Edoardo Savarino, Danila Guagnozzi, Isabel Pérez-Martínez, Antonia Perelló, Antonio Guardiola-Arévalo, Jesús Barrio, María Elena Betoré-Glaria, Carolina Gutiérrez-Junquera, Constanza Ciriza de los Ríos, Francesca Racca, Sonia Fernández-Fernández, Leonardo Blas-Jhon, Anne Lund Krarup, Susana de la Riva, Juan E. Naves, Silvia Carrión, Juan Armando Rodríguez Oballe, Natalia García-Morales, Sonsoles Tamarit-Sebastián, Pilar Navarro, Ángel Arias, Emilio J. Laserna-Mendieta
Publikováno v:
Therapeutic Advances in Gastroenterology, Vol 15 (2022)
Background: The growing prevalence of eosinophilic esophagitis (EoE) represents a considerable burden to patients and health care systems. Optimizing cost-effective management and identifying mechanisms for disease onset and progression are required.
Externí odkaz:
https://doaj.org/article/43db2724b56b4a728452b2fac2d7ffa2
Autor:
Elena Grueso-Navarro, Pilar Navarro, Emilio J. Laserna-Mendieta, Alfredo J. Lucendo, Laura Arias-González
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3669 (2023)
Eosinophilic esophagitis (EoE) is a chronic, Th2-inflammatory disease of the esophagus that can severely affect food intake. Currently, diagnosis and assessing response to treatment of EoE is highly invasive and requires endoscopy with esophageal bio
Externí odkaz:
https://doaj.org/article/5089a4d02b7e436986b42e3881a649fd
Autor:
Nicole R. Narayan, Thomas Weinmaier, Emilio J. Laserna-Mendieta, Marcus J. Claesson, Fergus Shanahan, Karim Dabbagh, Shoko Iwai, Todd Z. DeSantis
Publikováno v:
BMC Genomics, Vol 21, Iss 1, Pp 1-3 (2020)
Following the publication of this article [1], the authors reported errors in Figs. 1, 2 and 5. Due to a typesetting error the asterisks denoting significance were missing from the published figures.
Externí odkaz:
https://doaj.org/article/5335a9de2a8c4f519d4df7ca54e7ab13
Autor:
Emilio J. Laserna-Mendieta, María José Casanova, Ángel Arias, Laura Arias-González, Pedro Majano, Luis Alberto Mate, Carlos Humberto Gordillo-Vélez, Mirella Jiménez, Teresa Angueira, Emilia Tébar-Romero, María Jesús Carrillo-Ramos, María Ángeles Tejero-Bustos, Javier P. Gisbert, Cecilio Santander, Alfredo J. Lucendo
Publikováno v:
Nutrients, Vol 13, Iss 1, p 98 (2020)
A lifelong gluten-free diet (GFD) is the only current treatment for celiac disease (CD), but strict compliance is complicated. Duodenal biopsies are the “gold standard” method for diagnosing CD, but they are not generally recommended for disease
Externí odkaz:
https://doaj.org/article/712824f6f969441ba37ec21ba3eaf407
Autor:
Pedro Majano, Antonia Perelló, Edoardo Savarino, Matteo Ghisa, Danila Guagnozzi, Pilar Navarro, Cecilio Santander, Guillermo Ortega-Rabbione, Emilio J Laserna-Mendieta, Ángel Arias, Susana de la Riva, Carmen Alcolea-Valero, Natalia Serrano-Moya, Sergio Casabona, Alfredo J. Lucendo, José María Olalla
Publikováno v:
Digestive and Liver Disease. 53:1479-1485
Long-standing inflammation leads to esophageal remodeling with stricture formation in patients with eosinophilic esophagitis (EoE). The ability of proton pump inhibitors (PPI) to reverse endoscopic features of fibrosis is still unknown.To investigate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29d966b43959f50d23831b7eab67d131
https://doi.org/10.1016/j.dld.2021.05.025
https://doi.org/10.1016/j.dld.2021.05.025
Autor:
Adam G. Clooney, Julia Eckenberger, Kathryn A. Sexton, Kathy Vagianos, Laura E. Targownik, Roy D. Sleator, Marcus J. Claesson, Donal Sheehan, Charles N. Bernstein, Michael Sargent, Emilio J Laserna-Mendieta, Fergus Shanahan, Feargal J. Ryan, Carthage Moran, Matthew T Bernstein
Publikováno v:
Gut
Objective The microbiome contributes to the pathogenesis of inflammatory bowel disease (IBD) but the relative contribution of different lifestyle and environmental factors to the compositional variability of the gut microbiota is unclear. Design Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc3bc820241c1674fc74bcf6a66e79d7
https://doi.org/10.1136/gutjnl-2020-321106
https://doi.org/10.1136/gutjnl-2020-321106