Zobrazeno 1 - 10 of 63 pro vyhledávání: '"Emilio Itarte"'
1
Akademický článek
Effects of CK2β subunit down-regulation on Akt signalling in HK-2 renal cells.
Autor: Estefania Alcaraz, Jordi Vilardell, Christian Borgo, Eduard Sarró, Maria Plana, Oriano Marin, Lorenzo A Pinna, José R Bayascas, Anna Meseguer, Mauro Salvi, Emilio Itarte, Maria Ruzzene
Publikováno v: PLoS ONE, Vol 15, Iss 1, p e0227340 (2020)
The PI3K/Akt pathway is interconnected to protein kinase CK2, which directly phosphorylates Akt1 at S129. We have previously found that, in HK-2 renal cells, downregulation of the CK2 regulatory subunit β (shCK2β cells) reduces S129 Akt phosphoryla
Externí odkaz: https://doaj.org/article/69543d1d78a64740811782633ddbd0bf
Zobrazit plný text záznamu
2
Akademický článek
Targeting Protein Kinase CK2: Evaluating CX-4945 Potential for GL261 Glioblastoma Therapy in Immunocompetent Mice
Autor: Laura Ferrer-Font, Lucia Villamañan, Nuria Arias-Ramos, Jordi Vilardell, Maria Plana, Maria Ruzzene, Lorenzo A. Pinna, Emilio Itarte, Carles Arús, Ana Paula Candiota
Publikováno v: Pharmaceuticals, Vol 10, Iss 1, p 24 (2017)
Glioblastoma (GBM) causes poor survival in patients even with aggressive treatment. Temozolomide (TMZ) is the standard chemotherapeutic choice for GBM treatment but resistance always ensues. Protein kinase CK2 (CK2) contributes to tumour development
Externí odkaz: https://doaj.org/article/e670bbaecb9a42958d9d85d51579d85e
Zobrazit plný text záznamu
3
Akademický článek
KAP degradation by calpain is associated with CK2 phosphorylation and provides a novel mechanism for cyclosporine A-induced proximal tubule injury.
Autor: Olga Tornavaca, Eduard Sarró, Gloria Pascual, Beatriz Bardaji, M Angeles Montero, M Teresa Salcedo, Maria Plana, Joan López-Hellin, Emilio Itarte, Anna Meseguer
Publikováno v: PLoS ONE, Vol 6, Iss 9, p e25746 (2011)
The use of cyclosporine A (CsA) is limited by its severe nephrotoxicity that includes reversible vasoconstrictor effects and proximal tubule cell injury, the latter associated whith chronic kidney disease progression. The mechanisms of CsA-induced tu
Externí odkaz: https://doaj.org/article/ba9429455e464ae4a4261e9e29aa6d92
Zobrazit plný text záznamu
7
Up-Regulation of the Alpha Prime Subunit of Protein Kinase CK2 as a Marker of Fast Proliferation in GL261 Cultured Cells
Autor: Maria Ruzzene, Emilio Itarte, Lucia Villamañan, Ana Paula Candiota, Lorenzo A. Pinna, Maria Plana, Estefania Alcaraz, Carles Arús
Publikováno v: Pathology & Oncology Research. 25:1659-1663
Glioblastoma (GB) is the most prevalent malignant primary brain tumor in adults. The preclinical glioblastoma model GL261 is widely used for investigating new therapeutic strategies. GL261 cultured cells are used for assessing preliminary in vitro da
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8751b0e9a32f7424a3f9628622183961
https://doi.org/10.1007/s12253-018-00567-z
Zobrazit plný text záznamu
8
Effects of CK2β subunit down-regulation on Akt signalling in HK-2 renal cells
Autor: Christian Borgo, Lorenzo A. Pinna, Jose R. Bayascas, Mauro Salvi, Maria Ruzzene, Anna Meseguer, Emilio Itarte, Maria Plana, Oriano Marin, Jordi Vilardell, Eduard Sarró, Estefania Alcaraz
Publikováno v: Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
PLoS ONE, Vol 15, Iss 1, p e0227340 (2020)
PLoS ONE
The PI3K/Akt pathway is interconnected to protein kinase CK2, which directly phosphorylates Akt1 at S129. We have previously found that, in HK-2 renal cells, downregulation of the CK2 regulatory subunit β (shCK2β cells) reduces S129 Akt phosphoryla
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5627839cc3c2fab6d52958560ab7df56
https://ddd.uab.cat/record/226171
Zobrazit plný text záznamu
9
Under-expression of CK2β subunit in ccRCC represents a complementary biomarker of p-STAT3 Ser727 that correlates with patient survival
Autor: Juan Morote, Jordi Vilardell, Enric Trilla, Santiago Ramón y Cajal, Anna Meseguer, Inés de Torres, Estefania Alcaraz, Maria Ruzzene, Lorenzo A. Pinna, Eduard Sarró, Thais Cuadros, Emilio Itarte, Maria Plana
Publikováno v: Oncotarget
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Clear cell renal cell carcinoma (ccRCC) is the most common and aggressive subtype of renal cancer. STAT3 pathway is altered in these tumors and p-STAT3 Ser727 is an independent prognostic factor for ccRCC. Protein kinase CK2 is altered in different t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c161b6e1d568ceae30711b7efbcc098
https://pubmed.ncbi.nlm.nih.gov/29464030
Zobrazit plný text záznamu
10
Targeting protein kinase CK2 : evaluationg CX-4945 potential for GL261 glioblastoma therapy in immunocompetent mice
Autor: Maria Plana, Lorenzo A. Pinna, Lucia Villamañan, Jordi Vilardell, Laura Ferrer-Font, Carles Arús, Ana Paula Candiota, Emilio Itarte, Nuria Arias-Ramos, Maria Ruzzene
Publikováno v: Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Pharmaceuticals
Pharmaceuticals; Volume 10; Issue 1; Pages: 24
Pharmaceuticals, Vol 10, Iss 1, p 24 (2017)
Glioblastoma (GBM) causes poor survival in patients even with aggressive treatment. Temozolomide (TMZ) is the standard chemotherapeutic choice for GBM treatment but resistance always ensues. Protein kinase CK2 (CK2) contributes to tumour development
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efffe9daea5a891505c75a11a356f870
https://ddd.uab.cat/record/170144
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje