Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Emilio Fernandez Espejo"'
Publikováno v:
Pharmaceuticals, Vol 4, Iss 7, Pp 976-991 (2011)
Drugs of abuse induce plastic changes in the brain that seem to underlie addictive phenomena. These plastic changes can be structural (morphological) or synaptic (biochemical), and most of them take place in the mesolimbic and mesostriatal circuits.
Externí odkaz:
https://doaj.org/article/0e625778e38f403ebb289dfb3c4ef7d3
Autor:
Emilio Fernandez-Espejo, Isabel Caraballo, Fernando Rodriguez de Fonseca, Fadwa El Banoua, Belen Ferrer, Juan A. Flores, Beatriz Galan-Rodriguez
Publikováno v:
Neurobiology of Disease, Vol 18, Iss 3, Pp 591-601 (2005)
We have observed that systemic administration of cannabinoid CB1 antagonists exerts antiparkinsonian effects in rats with very severe nigral lesion (>95% cell loss), but not in rats with less severe lesion (85–95% cell loss). Local injections into
Externí odkaz:
https://doaj.org/article/d4f6dd23bfa64285972aef3ece602906
Autor:
Fadwa El Banoua, Isabel Caraballo, Juan A Flores, Beatriz Galan-Rodriguez, Emilio Fernandez-Espejo
Publikováno v:
Neurobiology of Disease, Vol 16, Iss 2, Pp 377-385 (2004)
Brain cannabinoid CB1 receptors are expressed in neural areas that contribute to movement such as basal ganglia, where they co-localize with dopamine D1 and D2 receptors. The objective of the present study was to further study the functional role of
Externí odkaz:
https://doaj.org/article/43dd1eb9526b4ba78e472037c064aba1
Autor:
Emilio Fernandez Espejo
Publikováno v:
Neuropsychopharmacology. 28:490-498
Prefrontal dopamine loss delays extinction of cued fear conditioning responses, but its role in contextual fear conditioning has not been explored. Medial prefrontal lesions also enhance social interaction in rats, but the role of prefrontal dopamine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcaaeefe97c49d2a4339ede401c4c0a7
https://doi.org/10.1038/sj.npp.1300066
https://doi.org/10.1038/sj.npp.1300066
Autor:
Miguel Angel, Gorriti, Belén, Ferrer, Ignacio, del Arco, Francisco Javier, Bermúdez-Silva, Yolanda, de Diego, Emilio, Fernandez-Espejo, Miguel, Navarro, Fernando, Rodríguez de Fonseca
Publikováno v:
Pharmacology, biochemistry, and behavior. 81(1)
The endogenous cannabinoid system works as a feedback signal controlling dopamine-induced facilitation of motor behaviors. The present study explored whether a single acute stimulation of CB1 cannabinoid receptors with (-)-Delta9-tetrahydrocannabinol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9005cd4ff9bd2e8daefa3010c43d3550
https://pubmed.ncbi.nlm.nih.gov/15894066
https://pubmed.ncbi.nlm.nih.gov/15894066
Autor:
George F. Koob, Umberto Spampinato, Stéphanie Caillé, Emilio Fernandez Espejo, Philippe De Deurwaerdère, Luis Stinus
Publikováno v:
Health and Addictions/Salud y Drogas. 3
El objetivo del estudio fue discernir el papel del sistema endógeno de serotonina en la abstinencia opiácea, tanto en su vertiente somática como emocional, así como su posible interacción con los efectos de la clonidina. Con tal fin, se empleó
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::145627880b34049b23c28ef876934823
https://doi.org/10.21134/haaj.v3i1.150
https://doi.org/10.21134/haaj.v3i1.150
Autor:
Emilio Fernandez Espejo, Isabel Caraballo, Juan A. Flores, Fadwa El Banoua, Joao-Paulo Moraes, M. Carmen Gonzalez-Albo
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 21(24)
Intrabrain transplantation of chromaffin cell aggregates of the Zuckerkandl's organ, an extra-adrenal paraganglion that has never been tested for antiparkinsonian treatment, induced gradual improvement of functional deficits in parkinsonian rats. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::171bbcc6971f85c8a39772756815c8e2
https://pubmed.ncbi.nlm.nih.gov/11739596
https://pubmed.ncbi.nlm.nih.gov/11739596